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Cosmetic containing recombinant human auxin liposome and preparation method of cosmetic

A technology of auxin lipid and auxin, which is applied in the field of cosmetics containing recombinant human auxin liposome, can solve the problems of unsatisfactory cosmetic application effect, poor effect of removing pigmentation, and short duration of cosmetics, etc., to prolong the drug effect Time, suitable for large-scale industrial production, the effect of anti-aging cells epidermal cells

Inactive Publication Date: 2020-09-04
上海圣岳生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as a protein hormone, rh-GH has the disadvantages of short half-life and poor stability. Clinical treatment requires frequent injections, and some patients have been observed to produce anti-growth hormone antibodies or hypersensitivity reactions.
[0003] In the Chinese invention application patent with the publication number CN1037455A, a cell recovery and bodybuilding cream is disclosed, which uses natural active proteins, such as human growth hormone, to replace the traditional use of 4-isopropyl catechol or aminomercuric chloride, hydrogen kiln , hydrogen ester monomethyl ether and other components of the cream, so as to solve the problems of skin irritation, poor effect of removing pigmentation and even skin allergies in traditional creams
[0004] However, as a protein hormone, recombinant human growth hormone has the disadvantages of short half-life and poor stability, and frequent injections are required for clinical treatment.
When it is directly applied to cosmetics, the resulting cosmetics have a short duration of action and poor stability, so the effect of the cosmetics is not ideal

Method used

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  • Cosmetic containing recombinant human auxin liposome and preparation method of cosmetic
  • Cosmetic containing recombinant human auxin liposome and preparation method of cosmetic
  • Cosmetic containing recombinant human auxin liposome and preparation method of cosmetic

Examples

Experimental program
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Effect test

Embodiment 1

[0051] Embodiment 1: as figure 1 , a body lotion containing recombinant human auxin liposome, each component and its corresponding parts by weight are shown in Table 1, and are prepared through the following steps:

[0052] S1, according to Table 1, water, glycerin, mineral oil, ethylhexyl palmitate, 6-aminonicotinamide, polydimethylsiloxane, polyglycerin, distearate and keratin Mix squalane and heat to 60°C;

[0053] S2, mixing the recombinant human auxin liposome and methylparaben, heating to 30°C;

[0054] S3, mix the materials obtained in step S1 and step S2, cool down to 35°C, stir evenly at 2000rpm, stir for 5min, and cool to 25°C to obtain.

[0055] In this example, recombinant human auxin liposomes were obtained by the following preparation steps:

[0056] Step 1, prepare the membrane material: dissolve 100mg of phospholipids and 49mg of cholesterol in 25mL of absolute ethanol, and ultrasonically dissolve for 20s to make a membrane material solution;

[0057] Step 2,...

Embodiment 2-6

[0059] Example 2-6: A body lotion containing recombinant human auxin liposome, the difference from Example 1 is that each component and its corresponding parts by weight are shown in Table 1.

[0060] Each component and parts by weight thereof in table 1 embodiment 1-6

[0061]

Embodiment 7

[0062] Embodiment 7: A body lotion containing recombinant human auxin liposome, the difference from Example 1 is that the body lotion is prepared through the following steps:

[0063] S1, according to Table 1, water, glycerin, mineral oil, ethylhexyl palmitate, 6-aminonicotinamide, polydimethylsiloxane, polyglycerin, distearate and keratin Mix squalane and heat to 75°C;

[0064] S2, mixing the recombinant human auxin liposome and methylparaben, heating to 40°C;

[0065] S3, mix the materials obtained in step S1 and step S2, cool down to 35°C, stir evenly at 2500rpm, stir for 10min, and cool to 30°C to obtain.

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Abstract

The invention discloses a cosmetic containing recombinant human auxin liposome and a preparation method of the cosmetic, and relates to the technical field of cosmetics. The technical key points are as follows: the cosmetic containing the recombinant human auxin liposome contains 1% to 0.1% by weight of the recombinant human auxin liposome. The cosmetic is a body lotion, and comprises the following components in parts by weight: 0.2-2.7 parts of the recombinant human auxin liposome; 5 to 10 parts of water; 40 to 50 parts of glycerol; 35 to 45 parts of mineral oil; 30 to 40 parts of ethylhexylpalmitate; 25 to 30 parts of 6-aminonicotinamide; 20 to 30 parts of polydimethylsiloxane; 20 to 30 parts of polyglycerol; 15 to 20 parts of distearate; 5 to 10 parts of squalane; 1 to 6 parts of sodium hyaluronate; and 1-2 parts of methylparaben. By adding the recombinant human auxin liposome into the body lotion and supplementing other auxiliary moisturizing materials, the cosmetic has the advantages of promoting cell repair, enhancing cell activity and endowing the skin with smoothness, tenderness and elasticity.

Description

technical field [0001] The invention relates to the technical field of cosmetics, more specifically, it relates to a cosmetic containing recombinant human auxin liposome. Background technique [0002] Recombinant human growth hormone (rhGH) is mainly used for growth disorders caused by insufficient secretion of endogenous growth hormone or Turner's syndrome and chronic renal insufficiency. At the same time, it also has various pharmacological effects such as improving the immune function of the body, promoting wound healing and promoting the regeneration of heart, liver, kidney, pancreatic islets and other viscera cells. At present, Shenzhen Kexing, Changchun Jinsai, Anhui Anke and other domestic enterprises produce it, and the dosage form is freeze-dried powder injection or injection. However, as a protein hormone, rh-GH has the disadvantages of short half-life and poor stability. Clinical treatment requires frequent injections, and some patients have been observed to prod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/14A61K8/64A61K8/67A61K8/06A61Q19/08A61Q19/00
CPCA61K8/14A61K8/64A61K8/678A61K8/06A61Q19/08A61Q19/00A61K2800/522A61K2800/805
Inventor 楼秀余吴锦青施明杰杨佩娟
Owner 上海圣岳生物科技有限公司
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