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External medicine for treating hormone-dependent dermatitis and preparation method thereof

A technology for dependent dermatitis and external use of drugs, applied in the field of medicine, can solve the problems of insufficient curative effect, insufficient retention of active ingredients, and insufficient use experience, and achieve the effect of avoiding skin use experience, high abundance and reasonable pH value.

Inactive Publication Date: 2020-08-21
北京赵桂荣中医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] On the one hand, the present invention provides a preparation method of an external drug for treating hormone-dependent dermatitis, which solves the technical problem that the existing preparation method of an external drug for treating hormone-dependent dermatitis does not retain enough active ingredients
[0017] Another aspect of the present invention provides a topical drug for treating hormone-dependent dermatitis, which solves the technical problems of insufficient curative effect and poor user experience of existing topical drugs for treating hormone-dependent dermatitis

Method used

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  • External medicine for treating hormone-dependent dermatitis and preparation method thereof

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preparation example Construction

[0042] One aspect of the embodiments of the present invention provides a preparation method of a topical medicine for the treatment of hormone-dependent dermatitis, such as figure 1 shown, including the following steps:

[0043] S01: 10-15 parts by weight of Panax notoginseng extract, 1-5 parts by weight of honeysuckle flower extract, 3-5 parts by weight of ginseng extract, 7-12 parts by weight of Kochia chinensis extract , 1-3 parts by weight of Chinese Ganoderma lucidum extract, 1-5 parts by weight of Polygonum multiflorum extract, 10-20 parts by weight of motherwort extract, 2-5 parts by weight of angelica extract, 1-3 parts by weight Parts of the Fritillaria fritillary extract and 1-3 parts by weight of the Sophora flavescens extract are dissolved in water to obtain a medicinal aqueous solution;

[0044] S02: adjusting the aqueous drug solution to weak acidity to obtain a drug stock solution;

[0045] S03: under the protection of low-temperature inert gas, the drug stock...

Embodiment 1

[0067] 10g Panax notoginseng extract, 1g honeysuckle extract, 3g ginseng extract, 7g Kochia extract, 1g Chinese Ganoderma lucidum extract, 1g Polygonum multiflorum extract, 10g Motherwort extract, 2g Angelica extract, 1g Fritillaria The extract and 2g of Sophora flavescens extract were dissolved in water to obtain a drug aqueous solution;

[0068] The drug aqueous solution is adjusted to pH 6.8 to obtain a drug stock solution;

[0069] The drug stock solution was concentrated to 1.3 g / mL under the protection of nitrogen gas at 5°C to obtain a drug concentrate;

[0070] It is diluted with water to 20 times the volume to obtain the external medicine for treating hormone-dependent dermatitis.

Embodiment 2

[0072] 12g Panax notoginseng extract, 3g honeysuckle flower extract, 4g ginseng extract, 10g Kochia extract, 2g Chinese Ganoderma lucidum extract, 4g Polygonum multiflorum extract, 15g motherwort extract, 3g angelica extract, 2.5g soil shell The mother extract and 1 g of Sophora flavescens extract are dissolved in water to obtain an aqueous drug solution;

[0073] The drug solution is adjusted to pH 6.5 to obtain a drug stock solution;

[0074] The drug stock solution was concentrated to 1.2 g / mL under the protection of argon gas at 8°C to obtain a drug concentrate;

[0075] It is diluted with water to 20 times the volume to obtain the external medicine for treating hormone-dependent dermatitis.

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Abstract

The invention provides an external medicine for treating hormone-dependent dermatitis and a preparation method thereof, and the preparation method comprises the following steps: dissolving extracted medicines and functional ingredients in water to obtain a medicine aqueous solution; adjusting a medicine aqueous solution to be weakly acidic to obtain a medicine stock solution; concentrating the medicine stock solution to 1.1-1.3 g / mL under the protection of low-temperature inert gas to obtain a medicine concentrated solution; and diluting the medicine concentrated solution with water to 20 times the volume of the medicine concentrated solution to obtain the external medicine for treating hormone-dependent dermatitis. According to the preparation method of the external medicine for treatinghormone-dependent dermatitis, the abundance of effective active ingredients is higher and more stable, meanwhile, the external medicine has a reasonable pH value and is milder, and the skin of a patient suffering from hormone-dependent dermatitis which is sensitive to the external medicine is prevented from being further stimulated. The user experience is better.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to an external medicine for treating hormone-dependent dermatitis and a preparation method thereof. Background technique [0002] With the improvement of people's living standards, people's use of cosmetics and medical beauty has gradually increased. However, some patients lack sufficient understanding, use some cosmetics containing glucocorticoids, or accept hormone therapy from unscrupulous merchants, and their skin conditions are significantly improved in a short period of time, but once they are stopped, inflammatory damage will occur, and they need to use sugar repeatedly. Corticosteroids are used to control symptoms and symptoms will gradually worsen with repeated use, a vicious circle. Clinical manifestations are: [0003] Epidermis and dermis thinning [0004] Local long-term topical application of hormones can lead to the reduction of the formation of stratum corneum ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61P17/00
CPCA61K9/0014A61K36/074A61K36/185A61K36/232A61K36/258A61K36/355A61K36/42A61K36/489A61K36/533A61K36/704A61K2236/331A61K2236/53A61P17/00A61K2300/00
Inventor 乔浩赵桂荣
Owner 北京赵桂荣中医药科技有限公司
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