Contrast agent for abdominal imageology examination
A contrast agent and abdominal technology, applied in the direction of X-ray contrast agent preparation, in vivo test preparations, radioactive carriers, etc., to achieve the effects of reducing absorption, improving safety, and easy application
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Embodiment 1
[0028] Embodiment 1 Preparation of contrast agent for abdominal imaging examination
[0029] Preparation of contrast agent for abdominal X-ray radiography in the experimental group: According to the composition of the experimental group in Table 1, each component was measured, and the contrast agent for abdominal X-ray radiography was prepared according to the following steps. Brief description of the preparation method: mix poloxamer P188 and poloxamer P407, add distilled water, mix well, place at 4°C for 12 hours, mix well again, add barium sulfate fine powder, disperse and mix well, and obtain abdominal X-ray radiography contrast agent.
[0030] Preparation of contrast medium for abdominal imaging examination in the control group: according to the composition of the control group in Table 1, the contrast medium for the abdominal imaging examination of the control group was prepared according to the method of the experimental group.
[0031] The composition of the abdominal...
Embodiment 2
[0034] Embodiment 2 Evaluation of imaging effect of contrast medium in abdominal imaging examination
[0035] Gastric imaging: Beagle dogs (weight 3kg / dog) were fasted for 18-24 hours before imaging, food and debris in the stomach were removed, and the dog was anesthetized by intramuscular injection of Sumianxin. Before the contrast, the X-ray machine took a plain film, and then injected 30% weight / volume ratio of X-ray radiographic contrast agent through the gastric catheter, and poured it in at 10mL / kg body weight. Then turn the animal over carefully, so that the barium meal is fully coated on the stomach wall (turn over 3 to 5 times to the left and right, lift up and down 2 to 3 times). Then inject air into the stomach at a rate of 8-10 mL / kg body weight, take out or clamp the outer end of the gastric tube, and then turn it over 1-2 times left and right, and immediately adopt the ventral dorsal position (dorsal abdominal position) and left side (right side) filming.
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