An oral medicine for regulating blood lipid, raising adiponectin and protecting liver
An adiponectin and blood lipid-regulating technology, applied in the directions of drug delivery, drug combination, pharmaceutical formulation, etc., can solve the problems of expensive western medicine and liver damage, and achieve the goal of reducing drug-induced liver damage, short production cycle, and reducing abdominal fat. Effect
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Embodiment 1
[0037]Take by weighing 20.00 kg of the above-ground part of pearl ginseng produced in September in Taibai County, Baoji City, Shaanxi Province, add 12 times its mass concentration and reflux extraction of 70% ethanol aqueous solution for 2 times, extract for 2 hours each time, filter, combine the filtrate, concentrate, Utilize D-101 macroporous resin column chromatography to purify the concentrated solution, elute with ethanol aqueous solution with volume concentration of 30%, 70%, and 95% successively, collect the eluate with volume concentration of 70% ethanol aqueous solution, concentrate and dry to obtain 854.48g (yield: 4.3%) of the extract of the aerial part of Ginseng. Through liquid chromatography analysis, the total saponin content in the aerial part extract of the obtained Pearl Ginseng is 86.25%, wherein ginsenoside Rb 2 The content is 17.39%, ginsenoside Rb 1 The content is 4.97%, ginsenoside Rg 1 The content is 5.41%, ginsenoside Rb 3 The content of ginsenoside...
Embodiment 2
[0043] Weigh 25.20 kg of the above-ground part of pearl ginseng produced in June in Taibai County, Baoji City, Shaanxi Province, add 10 times its mass and 50% ethanol aqueous solution for reflux extraction twice, extract for 1.5 hours each time, filter, filter and merge twice The filtrate was concentrated, and the concentrated solution was purified by D-101 macroporous resin column chromatography, followed by eluting with aqueous ethanol with a volume concentration of 10%, 30%, 50%, and 95%, and collecting the ethanol solution with a volume concentration of 50%. Deliquified, concentrated and dried to obtain 630.06 g (yield: 2.5%) of the aerial part extract of ginseng. Through liquid chromatography analysis, the total saponin content in the aerial part extract of the obtained Pearl Ginseng is 90.18%, wherein ginsenoside Rb 2 The content is 19.46%, ginsenoside Rb 1 The content is 5.51%, ginsenoside Rg 1 The content is 6.32%, ginsenoside Rb 3 The content of ginsenoside Rd is 5...
Embodiment 3
[0046] Weigh 63.00 kg of the above-ground part of pearl ginseng produced in May in Taibai County, Baoji City, Shaanxi Province, add 13 times its mass of 80% ethanol aqueous solution for reflux extraction twice, extract for 2.5 hours each time, filter, filter and merge twice The filtrate was concentrated, and the concentrated solution was purified by D-101 macroporous resin column chromatography, followed by eluting with aqueous ethanol with a volume concentration of 30%, 70%, and 95%, and collecting the eluate with a volume concentration of 95% aqueous ethanol, Concentrate and dry to obtain 614.25 g (yield: 1.0%) of the aerial part extract of Ginseng. Through liquid chromatography analysis, the total saponin content in the aerial part extract of the obtained Pearl Ginseng is 81.29%, wherein ginsenoside Rb 2 The content is 18.03%, ginsenoside Rb 1 The content is 4.50%, ginsenoside Rg 1 The content is 4.78%, ginsenoside Rb 3 The content of ginsenoside Rd is 4.43%, and the con...
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