A kit for guiding people's medication for depression and its application

Abstract

The invention provides a kit for guiding human depression drug use and an application thereof. The kit can be used for simultaneously typing 43 gene loci. The kit comprises 43 pairs of amplification primers for amplifying 43 gene segments, wherein the 43 gene loci are shown in a table, and the sequence of 43 pairs of amplification primers is shown in SEQ ID NO.1-SEQ ID NO.86. On the basis of research on large samples, a brand-new site combination is proposed, and accurate guidance and timely feedback are provided for treatment of depression from genes and genetic angles; based on the time-of-flight mass spectrometry technology, genotyping is carried out, and some genes and mutation sites which are most relevant to carefully selected and depressive drugs are subjected to medium flux sequencing, so that the detection time and cost can be greatly reduced, and a highly reliable detection result can still be obtained, so that a highly important clinical application value is achieved.

Description

technical field [0001] The invention relates to the field of reagent kits, and more particularly relates to a reagent kit for instructing people to treat depression and its application. Background technique [0002] Depression is one of the leading mental illnesses worldwide, with a greater impact on health than chronic diseases such as diabetes. Studies have shown that about 20% of patients with depression cannot receive effective treatment, and about 50% of patients will experience long-term torture or recurrence of depression, which seriously affects the lives of patients. [0003] Medication guidance for the treatment of depression involves two main steps: gene variation detection and result interpretation. [0004] Gene mutation detection: At present, the main methods of gene detection include mutation detection based on PCR technology and mutation detection based on next-generation sequencing technology. Detection based on PCR technology also includes fluorescent qua...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a test kit for instructing people to take medication for depression and its application, so as to solve the problem of high cost, insufficient accuracy, low detection efficiency, incomplete coverage of domestic depression treatment drugs, and inability to provide Questions about comprehensive medication guidance

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