Traditional Chinese medicine composition for clearing away heat and toxic materials and removing stasis, and preparation method thereof

A heat-clearing and detoxifying composition technology, applied in the field of anti-liver tumor and its complication composition, can solve the problems of lack of traditional Chinese medicine preparations and treatment means, difficult to achieve treatment goals, poor treatment effect, etc., to make up for the shortage of natural protein, The effect of repairing liver cell function and improving body adaptability

Active Publication Date: 2020-06-19
谢昌杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Chemotherapy drugs such as fluorouracil, oxaliplatin, and gemcitabine, etc., most of which are not effective
[0010] Chinese patent medicines such as Cinochansu Capsules, Jinlong Capsules, Yangzheng Xiaoji Capsules, etc., have mediocre effects and are difficult to achieve the purpose of treatment
[0011] Liver cancer patients often have various complications, which are life-threatening and increase the difficulty of medication
[0012] At present, the radical cure of hepatitis, cirrhosis and liver cancer is still a weak link, and there is a lack of effective traditional Chinese medicine preparations and treatment methods. It is urgent to develop a new drug that is safe and effective, and treats the symptoms and cures the disease to meet the needs of clinical treatment of liver-related diseases.

Method used

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  • Traditional Chinese medicine composition for clearing away heat and toxic materials and removing stasis, and preparation method thereof
  • Traditional Chinese medicine composition for clearing away heat and toxic materials and removing stasis, and preparation method thereof
  • Traditional Chinese medicine composition for clearing away heat and toxic materials and removing stasis, and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0074] Embodiment 1-4, the formula of the heat-clearing and toxic substances removing composition of the present invention is as follows:

[0075]

[0076]

[0077] The preparation method of the Chinese medicine composition of embodiment 1-4 comprises the steps:

[0078] (1) Crush Tutianqi, an umbrella, tangerine rice, honey beetle, elm root white bark, and persimmon leaves to a particle size of 50-80 mesh;

[0079] (2) Mix the above pulverized raw materials, add ethanol aqueous solution and soak for 3-5 hours;

[0080] (3) Add clear water to the above mixture and decoct for 3 times, the first decoction time is 60 minutes, the second decoction time is 45 minutes, and the third decoction time is 30 minutes. The clear water decocting in the step (3) is decocting 3 times, the decocting time for the first time is 60 minutes, the time for the second decoction is 45 minutes, and the time for the third time is 30 minutes. Filter to remove the filter residue, make a decoction ...

example 1

[0110]Example 1. Male, 40 years old, in poor spirits, inconvenient to move, swollen face, yellow staining of sclera, occult blood in fundus, frequent epistaxis, pain in liver area and spleen area. Ways to discover hepatitis B: physical examination. Route of hepatitis B infection: Chief complaint is unknown. Medical history: Suffering from hepatitis B for about 10 years, history of liver cirrhosis, chief complaint is unknown. Liver cirrhosis was detected in March 1999. Family medical history and hereditary and functional genetic predisposition: both parents have liver disease.

[0111] Immunological examination: On December 12, 2002, hepatitis B surface antigen (HBsAg) was positive, hepatitis B e antigen (HBeAg) was positive, and hepatitis B core antibody (HBcAb) was positive.

[0112] HBV-DNA inspection: December 12, 2002, 9.34×10 6 copies / ml.

[0113] Blood biochemical examination: December 12, 2002, alanine aminotransferase 62IU / L, aspartate aminotransferase 82IU / L, tot...

example 2

[0121] Example 2. Male, 27 years old, fatigue, easy to catch a cold, fundus occult blood, bitter mouth, dry mouth, hot hands and feet. Ways to discover hepatitis B: premarital examination. Route of hepatitis B infection: Chief complaint is unknown. Medical history: The history of hepatitis B is about 2 years. History of gastric ulcer for many years. Family medical history and hereditary and functional genetic predisposition: none or my father suffers from hepatitis B (the main complaint is confidential).

[0122] Immunological examination: On December 18, 2002, hepatitis B surface antigen (HBsAg) was positive, hepatitis B e antibody (HBcAg) was positive, and hepatitis B core antibody (HBcAb) was positive.

[0123] HBV-DNA examination: December 18, 2002, 1.0×10 5 copies / ml.

[0124] Previous treatment: Complaint of no treatment.

[0125] Current diagnosis: chronic hepatitis B small three yang.

[0126] Now taking traditional Chinese medicine A: started on December 23, 20...

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Abstract

The invention discloses a traditional Chinese medicine composition for clearing away heat and toxic materials and removing stasis, and a preparation method thereof. The composition includes involucrate stahlianthus rhizome, rose rhodobryum herb, tangerine seeds, Chinese honey bee larva, bark of elm tree and persimmon leaf. The composition can enhance organism adaptation and digestive organ functions, improve insufficiency of the spleen and promote tissue metabolism; the composition has the efficacy of clearing away heat and toxic materials and removing stasis; in animal experiments, high and low dose groups have a certain inhibition effect on liver tumor, the physiological status of mice is good, and the survival rates of 45 days are respectively 100% and 80%; the composition has no toxicand side effects on human bodies, and can strengthen nutrition, inhibit liver tumor, repair hepatocyte functions, reverse liver cirrhosis and reduce the mortality of severe hepatitis; and the composition has synchronous therapeutic effects on complications of the liver tumor.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for clearing heat, detoxifying, dispelling blood stasis and resolving stagnation and a preparation method thereof, in particular to an anti-liver tumor and its complication composition prepared from natural animals and plants. Background technique [0002] The etiology of liver tumors, especially primary liver cancer, has not been fully elucidated so far. Viral hepatitis, especially hepatitis B, liver cirrhosis, and liver cancer are a trilogy of migration and evolution. When typical symptoms such as fever, fatigue, vomiting, hemoptysis, pain in the liver area, abdominal distension, and diarrhea appear, it often indicates that the disease is in an advanced stage and there are serious complications. Treatment of liver-related diseases generally involves the following approaches: [0003] Liver resection can completely remove tu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61P35/00A61P1/16A61K35/64
CPCA61K36/906A61K36/54A61K36/752A61K35/64A61K36/185A61K36/44A61P35/00A61P1/16A61K2236/333A61K2236/39A61K2236/331A61K2300/00Y02A50/30
Inventor 谢昌杰
Owner 谢昌杰
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