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Herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation diminishing composition for treating cold, pneumonia, enteritis and nephritis

A composition, the technology of Pulmonaria pulmonata, applied in the direction of drug combination, anti-toxic agent, anti-inflammatory agent, etc., can solve the problems of large side effects, unsatisfactory drug efficacy, and urgent development of the advantages of traditional Chinese medicine

Inactive Publication Date: 2020-06-16
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many drugs for the treatment of pneumonia, most of which are western medicines, and western medicine is the main treatment. However, these drugs have relatively large side effects, and their efficacy is not satisfactory. The virus clearance rate is low and the recurrence rate is high. Antiviral drugs cannot completely clear the virus The replicated template gives the virus the conditions to re-transcribe and replicate, and the virus is prone to mutation and drug resistance
Traditional Chinese medicine emphasizes dialectical treatment and the combination of disease and syndrome. It has its own characteristics and advantages in the treatment of pneumonia accompanied by enteritis and nephritis. There are few applications. It can be said that the advantages of traditional Chinese medicine in the treatment of pneumonia accompanied by enteritis and renal inflammation need to be developed urgently

Method used

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  • Herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation diminishing composition for treating cold, pneumonia, enteritis and nephritis
  • Herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation diminishing composition for treating cold, pneumonia, enteritis and nephritis
  • Herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation diminishing composition for treating cold, pneumonia, enteritis and nephritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Influenza virus and coronavirus infection will lead to host cell degeneration, necrosis and even shedding, resulting in mucosal hyperemia, edema and increased secretions, resulting in nasal congestion, runny nose, sore throat, dry cough and other symptoms of upper respiratory tract infection. When the virus spreads to the lower respiratory tract , may cause bronchiolitis and interstitial pneumonia. Among them, influenza virus and coronavirus infection can cause symptoms such as fever, chills, and vomiting. Infected patients may also have fever (body temperature higher than 38 degrees Celsius) and cough symptoms. Coronavirus has the tropism of gastrointestinal tract, respiratory tract and nervous system, and complications are more common in the elderly and chronic disease (cardiovascular disease, chronic bronchitis, enteritis, nephritis and diabetes, etc.) patients.

[0024] However, our country is rich in Chinese herbal medicine resources, has thousands of years of valu...

Embodiment 2

[0041] A detoxification and anti-inflammation composition of Pulmonaria Pulmonata and Yinqiao for the treatment of colds, pneumonia, enteritis and nephritis, characterized in that it consists of 10-20 parts of Pulmonaria Pulmonata, 10-20 parts of Flos Lonicera, and 20-40 parts of Forsythia 10-20 parts of Gardenia or Gardenia, 10-20 parts of Eucommia or Eucommia leaves, 10-20 parts of Sanbaicao, 10-20 parts of Daidaihua, ground into 20-400 mesh powder, And add an appropriate amount of pharmaceutical adjuvants, make oral liquid, granules, capsules, tablets, effervescent tablets, syrup, pills, ointment, Soft capsules, ointments, emulsions, powders, sustained-release agents, controlled-release agents, targeted preparations, powder injections, water injections, injections, nebulizers, microemulsions, gels, and nano-preparations.

[0042] 1) More specifically, according to mass percentage, 20 parts of lungwort, 10 parts of honeysuckle, 20 parts of forsythia, 10 parts of gardenia, 10...

Embodiment 3

[0049] An extract of Pulmonaria pulmonata detoxification and anti-inflammatory composition for treating colds, pneumonia, enteritis, and nephritis, characterized in that: take the composition in Example 2 or the powder that is ground from the composition, and use 0-100 Soak in % ethanol for 0.5-2 hours, heat reflux with 4-12 times the amount of solvent (the decoction method can be used when water is the solvent), extract 2-4 times, each time for 1-3 hours, filter, and combine the filtrates. Concentrate under reduced pressure at ℃ to obtain the extract, which is the extract of Pulmonaria Pulmonata Yinqiao Detoxification and Anti-inflammatory Composition for the treatment of colds, pneumonia, enteritis, and nephritis, and add appropriate amount of pharmaceutical excipients to make Pulmonaria Pulmonata according to the requirements of Example 1 Oral liquid, granules, capsules, tablets, effervescent tablets, syrup, pills, ointment, soft capsule, ointment, emulsion, powder, sustaine...

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Abstract

The invention relates to a herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation-diminishing composition for treating cold, pneumonia, enteritis and nephritis. The herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation-diminishing composition is prepared from, by mass, 10-20 parts of herba tripterospermi, 10-20 parts of flos lonicerae,20-40 parts of fructus forsythiae, 10-20 parts of fructus gardeniae or gardenia jasminoides, 10-20 parts of cortex eucommiae or folium cortex eucommiae, 10-20 parts of saururus chinensis and 10-20 parts of seville orange flowers, and an appropriate amount of pharmaceutic adjuvants. When the disease suddenly occurs, a patient mainly has the symptoms of upper respiratory virus infection history, abdominal distension or enteritis diarrhea or vomiting, nephritis and the like, and the natural course of the disease is 7-14 days. The characteristics and advantages of traditional Chinese medicine treatment of pneumonia accompanied by dialectical therapy and disease and symptom combination of enteritis and nephritis are brought into play, and the invention provides a preparation method of the herba tripterospermi, honeysuckle and fructus forsythiae detoxifying and inflammation diminishing composition for treating cold, pneumonia, enteritis and nephritis and application of the composition in preparation of the medicine for treating cold, pneumonia, enteritis and nephritis. The invention provides a new preparation process, specific new application and new efficacy of the tripterospermum tenuifolium and lonicera and forsythia detoxifying and inflammation-diminishing composition.

Description

technical field [0001] The invention relates to a preparation method of a detoxification and anti-inflammatory composition of Pulmonaria pulmonata and Yinqiao for treating colds, pneumonia, enteritis and nephritis and its application in the preparation of medicines for treating colds, pneumonia, enteritis and nephritis, which belongs to the preparation technology of traditional Chinese medicine field. Background technique [0002] Pneumonia—the name of the disease and syndrome comes from "The Complete Book of Measles for Living People". Pneumonia is one of the common diseases in internal medicine and pediatrics. Pneumonia refers to the inflammation of terminal airways, alveoli and pulmonary interstitium. It can be caused by pathogenic microorganisms such as bacteria, viruses, fungi, and parasites, as well as physical and chemical factors such as radiation and inhaled foreign bodies. The main clinical symptoms are fever, cough, expectoration, bloody sputum, which may be acc...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61P11/00A61P1/00A61P13/12A61P31/16A61P31/14A61P29/00A61P39/02
CPCA61K36/355A61K36/46A61K36/51A61K36/634A61K36/744A61K36/752A61K36/78A61P1/00A61P11/00A61P13/12A61P29/00A61P31/14A61P31/16A61P39/02A61K2300/00
Inventor 张忠立左月明
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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