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Titanium-nickel alloy material with high blood compatibility and preparation method thereof

A titanium-nickel alloy, compatible technology, used in metal processing equipment, welding equipment, manufacturing tools, etc., can solve the problems of reduced heparin activity, chemical pollution, and easy coating fall off by anticoagulant drug fixation. Fibrin adhesion, improved antibacterial properties, and improved adhesion properties

Pending Publication Date: 2020-05-19
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The purpose of the present invention is to provide a high blood compatibility titanium-nickel alloy material and its preparation method, build a porous structure on the surface of the titanium-nickel alloy, and then pour lubricating oil to form a porous super-slip surface, which can improve the blood compatibility of the titanium-nickel alloy In order to solve the technical problems of easy peeling of the coating and local corrosion of the peeling point of the existing coating method, the reduction of the activity of heparin in the anticoagulant drug immobilization method, and the pollution of the chemical method

Method used

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  • Titanium-nickel alloy material with high blood compatibility and preparation method thereof
  • Titanium-nickel alloy material with high blood compatibility and preparation method thereof
  • Titanium-nickel alloy material with high blood compatibility and preparation method thereof

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preparation example Construction

[0047] see figure 1 and image 3 In (a), the preparation method for preparing the above-mentioned highly blood-compatible titanium-nickel alloy material includes the following steps:

[0048] Step 1: The femtosecond laser 1 generates the femtosecond laser, and then the axicon lens 2 spatially shapes it into a conical light field distribution of the Bessel profile;

[0049] Step 2: The conical light field of the Bessel profile output by the axicon 2 is collimated by the first lens 3 to form a parallel laser beam, and then through the micromachining system 4, it is focused on the titanium laser beam fixed on the three-dimensional processing table 5. Nickel alloy material 6 surface;

[0050] Step 3: Control the movement of the three-dimensional processing table 5, and the beam focused on the surface of the titanium-nickel alloy material 6 processes a uniformly distributed porous structure on the surface of the titanium-nickel alloy material 6;

[0051] Step 4: inject lubricati...

specific Embodiment

[0054] (1) femtosecond laser 1 produces femtosecond laser, and its femtosecond laser is that wavelength is 1030nm, and pulse width is 400fs-10ps, and output frequency is the red light of 25KHz-5MHz; Then the model manufactured by Thorlabs is AX-250, The axicon lens 2 with the apex angle α of 1° is spatially shaped into a conical light field distribution with a Bessel profile; in this embodiment, the femtosecond laser 1 is a FemtoYL-40 laser, and in addition to selecting the FemtoYL-40 laser, you can also choose YSLP laser or other lasers; the specific parameters of femtosecond laser 1 are set as follows: the frequency is set to 2500KHz, the frequency is selected by the signal generator to 2KHz, the high level is triggered, the duty cycle is 20%, and the power is 2170mW;

[0055] (2) The conical light field of the Bessel profile output by the axicon 2 is collimated by the first lens 3 to form a parallel laser beam, and then through the micromachining system 4, it is focused on t...

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Abstract

The invention relates to a titanium-nickel alloy material and a preparation method thereof, in particular to a titanium-nickel alloy material with high blood compatibility and a preparation method thereof. The material and the method solve the technical problems that at present, by applying a coating method, a coating is prone to fall off and local corrosion at a point with the coating falling offis generated, by applying an anticoagulant drug fixation method, the activity of heparin is reduced, and by applying a chemical method, pollution is generated. The titanium-nickel alloy material withthe high blood compatibility is characterized by comprising a titanium-nickel alloy substrate, wherein uniform porous structures are distributed in the surface of the titanium-nickel alloy substrate,the porous structures are formed by adopting femtosecond laser ablation, and lubricating oil fills the porous structures. The invention also provides the preparation method of the titanium-nickel alloy material with the high blood compatibility. The titanium-nickel alloy material with the high blood compatibility can be applied to medical implantation and blood contact equipment.

Description

technical field [0001] The invention relates to a titanium-nickel alloy material and a preparation method thereof, in particular to a high blood compatibility titanium-nickel alloy material and a preparation method thereof. Background technique [0002] Although medical implants and devices in contact with blood have saved countless lives, there have always been problems with blood compatibility, that is, coagulation reactions caused by implant materials, high hemolysis rates, and inflammatory reactions. When implanted materials contact with blood in the body, it is easy to cause the adsorption of non-specific proteins, thereby activating the blood coagulation reaction and forming thrombus, which will directly threaten the life of the human body in severe cases. In order to ensure the long-term stability of implant materials, long-term anticoagulation treatment is particularly important. However, the existing anticoagulant means (such as taking drugs) are often accompanied ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B23K26/06B23K26/064B23K26/352
CPCB23K26/352B23K26/355B23K26/064B23K26/0648
Inventor 陈烽成扬杨青雍佳乐
Owner XI AN JIAOTONG UNIV
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