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Liquid wound spray dressing and preparation method thereof

A technology for wounds and sprays, applied in the fields of medical formula, medical science, drug delivery, etc., can solve few problems such as antibacterial, hemostasis, and promotion of wound healing, so as to achieve durable resistance to bacterial infection, good practical value and significance of popularization and application. Promotes film-forming protective effect

Active Publication Date: 2020-05-19
海南妙音春制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing liquid dressing products are generally used to prevent infection, and rarely have the effect of antibacterial, hemostasis, and promotion of wound healing. Wound healing still depends on the body's own repair function, so the application effect of this type of dressing product has a lot of room for improvement

Method used

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  • Liquid wound spray dressing and preparation method thereof
  • Liquid wound spray dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A liquid wound spray dressing, containing the following raw material components in percentage by weight: 0.8% silver sulfadiazine, 0.5% lidocaine hydrochloride, 3% chitosan, 6% polyvinyl alcohol, 10% ethanol, 0.8% sodium benzoate , the balance of purified water.

[0030] The preparation method of described liquid wound spray dressing, comprises the following steps:

[0031] (1) Soak polyvinyl alcohol with an appropriate amount of purified water for 1.5 hours, heat at a constant temperature of 90°C until dissolved, and stir evenly to obtain solution A;

[0032] (2) Chitosan is added into an appropriate amount of purified water, soaked, dispersed and dissolved to obtain solution B;

[0033] (3) Sodium benzoate is dissolved in ethanol to obtain solution C;

[0034] (4) Add solution B and solution C to solution A in sequence, then add silver sulfadiazine and lidocaine hydrochloride, make up to a sufficient amount of purified water, and stir evenly.

Embodiment 2

[0036] A liquid wound spray dressing, containing the following raw material components in percentage by weight: 1.2% silver sulfadiazine, 0.8% lidocaine free base, 1% chitosan, 3% polyvinyl alcohol, 8% ethanol, p-hydroxybenzene Methyl formate 0.6%, the balance in purified water.

[0037] The preparation method of the liquid wound spray dressing is the same as in Example 1.

Embodiment 3

[0039] A liquid wound spray dressing, containing the following raw material components in percentage by weight: 1% silver sulfadiazine, 0.7% lidocaine hydrochloride, 2% chitosan, 5% polyvinyl alcohol, 12% ethanol, p-hydroxybenzoic acid Ethyl ester 0.8%, purified water balance.

[0040] The preparation method of the liquid wound spray dressing is the same as in Example 1.

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Abstract

The invention belongs to the field of medical dressings, and particularly relates to a liquid wound spray dressing and a preparation method thereof. The liquid wound spray dressing comprises raw material components of silver sulfadiazine, lidocaine, chitosan, polyvinyl alcohol, ethanol, a preservative, purified water and the like. By optimal design of the component types, proportion and preparation method, long-term bacteriostasis and hemostasis of the liquid wound dressing can be improved, invasion of bacteria can be resisted for a long time, orderly growth and texture repair of wound tissuecan be prompted, and the wound healing process can be accelerated. The liquid wound dressing has definite curative effect, is safe and reliable to use and non-irritant to skin, and has better practical value and popularization and application significance, and the preparation method is quick and simple.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a liquid wound spray dressing and a preparation method thereof. Background technique [0002] Wound dressing is a covering or protective layer used for wounds. During wound healing and treatment, it can replace damaged skin to obtain temporary protection, avoid or control wound infection, and provide a suitable healing environment for the wounded surface. With the aging of the global population and the increase of chronic diseases in recent years, the incidence of chronic wounds has increased. With the advancement of science and technology, the wound care methods in clinical medicine also tend to require more efficient care methods. The traditional general dressings such as bandages, gauze, and cotton balls in the past are no longer sufficient to cope with the large and diverse wound conditions in modern times. There is a need for more efficient wound recovery medical materials ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0023A61L26/0061A61L26/0066A61L26/0076A61L2300/104A61L2300/402A61L2300/404A61L2400/04C08L5/08C08L29/04
Inventor 赖海杰李万江吴友世
Owner 海南妙音春制药有限公司
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