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Traditional Chinese medicine composition as well as preparation method and application thereof

The technology of a composition and traditional Chinese medicine is applied in the field of the composition of Chinese herbal medicines cinnamon twig and tuckahoe, and can solve the problems of high dust removal requirements, poor dissolution rate, low content of active ingredients and the like

Active Publication Date: 2020-03-10
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The preparation method of Guizhi Fuling Capsules disclosed in the prior art is mainly made by steam distillation, ethanol extraction, concentration, granulation, drying and other steps from Guizhi, Radix Paeoniae Alba, Poria cocos, peach kernel and Moutan bark according to the required weight ratio. Capsules, the defect is: the active ingredient content of the medicine prepared by this method is relatively low, the dissolution rate is poor, the production efficiency is low, the noise is large, and the dust removal requirements are high; therefore, it is necessary to improve the existing process to obtain the active ingredient APIs or preparations with high content

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

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Experimental program
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Effect test

Embodiment 1

[0085] The preparation of embodiment 1 composition capsule of the present invention

[0086] 1. Standard prescription for capsules

[0087]

[0088] 2. Production prescription (400 prescriptions)

[0089]

[0090] 3. Specific preparation method

[0091] pre-processing

[0092] Pre-processing 1:

[0093] The peony cortex in the above five-flavored medicines is washed with water for 2 minutes, dried, cut into pieces with a size of 0.5-1cm, and prepared for feeding;

[0094] The rest of the medicinal materials are pure medicinal materials for decoction;

[0095] Weigh 55% Poria cocos pieces for extraction. or,

[0096] Pre-processing 2:

[0097] The above-mentioned five kinds of medicinal materials are pure medicinal materials for decoction;

[0098] Weigh 55% of the Poria cocos decoction pieces of the prescription for extraction.

[0099] (a) Poria cocos powder intermediate preparation

[0100] Take a sufficient amount of Poria cocos, dry it at 70°C until the wat...

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Abstract

The invention discloses a traditional Chinese medicine composition. The traditional Chinese medicine composition is characterized by being prepared from ramulus cinnamomi, poria, cortex moutan radicis, paeoniae radix and peach seed according to an equal ratio, and the traditional Chinese medicine composition comprises paeoniflorin, amygdalin, benzoylpaeoniflorin, cinnamic acid, paeonol and cinnamaldehyde. The composition has high production efficiency, a high content of effective ingredients, a high transfer rate of pachymic acid, reduced hygroscopicity, and improved dissolution of the index components.

Description

technical field [0001] The invention relates to a composition comprising Chinese herbal medicines cinnamon twig (Ramulus cinnamomi) and poria cocos (Poria cocos), and a preparation method and application thereof. Background technique [0002] Guizhi Fuling Capsule is composed of five traditional Chinese medicines including Guizhi, Poria, Cortex Moutan, Paeoniae Alba and Peach Kernel. It has the effects of promoting blood circulation, removing blood stasis and eliminating symptoms. Endless postpartum lochia; uterine fibroids, chronic pelvic inflammatory mass, dysmenorrhea, endometriosis, ovarian cysts see the above syndromes; it can also be used for female breast sachet hyperplasia, which belongs to blood stasis syndrome, syndrome See breast pain, breast lump, chest rib distension; or be used for benign prostatic hyperplasia, which belongs to stasis bladder syndrome, symptoms include dysuria, abdominal distension and pain. [0003] The preparation method of Guizhi Fuling Cap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K47/69A61P7/04A61P15/00A61P35/00
CPCA61K36/54A61K36/076A61K36/71A61K36/65A61K36/736A61K47/6951A61P15/00A61P7/04A61P35/00A61K2236/37A61K2300/00C08B37/0015A61K31/12A61K9/1664A61K9/1694A61K9/4875A61K9/0053Y02A50/30A61K36/90A61K47/40A61P19/02A61K2236/15A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2236/55
Inventor 肖伟王正宽程宁波王振中朱克近
Owner JIANGSU KANION PHARMA CO LTD
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