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In vivo degradable magnesium alloy anastomosis nail and preparation method thereof

A staple and magnesium alloy technology, applied in the field of medical devices, can solve problems such as the lack of clear explanation of the influence of rare earth elements, fast degradation rate of magnesium alloy, and operation failure, etc., and achieve good comprehensive mechanical properties and biocompatibility, good Biosafety, the effect of avoiding mental and economic stress

Pending Publication Date: 2020-01-17
LANZHOU UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Rare earth elements will accumulate in the human body, and the impact of rare earth elements on the human body has not yet been clearly stated
(2) The mechanical properties of magnesium and its alloys need to be further improved to meet the requirements of in vivo use
(3) The degradation rate of magnesium alloy is too fast, and it usually degrades and fails before the human tissue is fully recovered, resulting in the failure of the operation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] The preparation method of the in vivo degradable alloy staple of the present invention, its steps are:

[0027] (1) Put the Mg, Zn, and Ca used in a drying oven to dry;

[0028] Melt pure magnesium in a vacuum induction melting furnace protected by argon, add Zn and Ca in sequence according to the above ratio, and cast after stirring and heat preservation to obtain a casting billet;

[0029] (2) Turning the casting billet to obtain a machined bar with a set size;

[0030] (3) Put the machined bar into a heat treatment furnace with a temperature of 400°C, keep it warm for 12 hours, perform homogenization treatment, and cool with the furnace;

[0031] (4) Heat the homogenized bar to 250°C and put it into a preheated mold for extrusion with an extrusion ratio of 25 to obtain an extruded bar;

[0032] (5) The extruded rods are subjected to solution treatment in a heat treatment furnace at 410 ° C ~ 420 ° C, kept for 16 hours, and then air-cooled;

[0033] (6) Multi-pass ...

Embodiment 1

[0037] (1) Put the used Mg, Zn and Ca into a drying oven for drying. Heat pure magnesium to 700°C in a vacuum induction melting furnace with argon protection. After the pure magnesium is completely melted, add Zn and Ca according to the composition requirements and raise the temperature to 750°C for 20 minutes. After stirring for 2 minutes, let it stand and cool down to Casting at 700°C to obtain ingots;

[0038] (2) Turning the cast ingot to obtain a machined bar of Φ40×50mm;

[0039] (3) Put the machined bar into a heat treatment furnace with a temperature of 400°C, keep it warm for 12 hours, perform homogenization treatment, and cool with the furnace;

[0040] (4) Heat the homogenized rod to 250°C and put it into a preheated mold for extrusion, with an extrusion ratio of 25, to obtain a Φ8mm extruded rod;

[0041] (5) The extruded rods are subjected to solution treatment in a heat treatment furnace at 410 ° C ~ 420 ° C, kept for 16 hours, and then air-cooled;

[0042] (6...

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Abstract

The invention relates to an in vivo degradable magnesium alloy anastomosis nail and a preparation method thereof. Used magnesium alloy comprises the following ingredients in percentage by mass: 2.0 to5.0 percent of Zn, 0.2 to 1.0 percent of Ca and the balance of Mg. The preparation method comprises the following steps of drying the used Mg, Zn and Ca; melting pure Mg in a vacuum induction meltingfurnace in which argon gas is introduced for protection; sequentially adding the Zn and the Ca according to the proportion; after stirring and heat insulation, performing casting to obtain a castingblank; machining the casting blank into a bar material; putting the bar material into a heat treatment furnace with the temperature of 400 DEG C; performing heat insulation for 12h; performing homogenization treatment; heating the bar material to 250 DEG C; putting the bar material into a preheated mold for extrusion at the extrusion ratio of 25; performing solid solution treatment on the bar material obtained through extrusion in the heat treatment furnace of 410 DEG C to 420 DEG C; performing heat insulation for 16h; drawing the treated bar material; obtaining a wire material through cooperation with an intermediate annealing process; and further processing the wire material to obtain the anastomosis nail for an anastomat.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an in vivo degradable magnesium alloy staple and a preparation method thereof. Background technique [0002] Staples are medical devices used clinically to suture human skin and tissues. Most of the staple materials currently used are titanium alloys. After titanium alloy staples are implanted in the human body, the debris produced by wear and tear will cause local allergies or inflammation in the human body. reaction, causing adverse effects on the human body. Titanium alloy has excellent corrosion resistance. Titanium alloy staples will exist for a long time after being implanted in the human body, which will affect the results of CT and MRI detection. Therefore, this type of staples must be removed after the human tissue is healed. The pain caused by the secondary injury, but also increased the cost of surgery. [0003] Based on the above problems, relevant technical personnel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/14A61L31/02C22C23/04C22C1/02
CPCA61L31/022A61L31/14A61L31/148C22C1/02C22C23/04
Inventor 丁雨田张鸿飞高钰璧王兴茂陈建军雷健
Owner LANZHOU UNIVERSITY OF TECHNOLOGY
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