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Traditional Chinese medicine composition with efficacy of sleep improvement and preparation method

A technology for improving sleep and composition, which is applied in the field of traditional Chinese medicine composition with sleep-improving function, to achieve the effect of improving sleep effect, improving sleep quality and improving sleep

Active Publication Date: 2019-09-20
SHANXI PROVINCE FOOD & DRUG INSPECTION INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, no other literature and patents have been published to report the health food that uses this formula to improve the sleep of the human body

Method used

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  • Traditional Chinese medicine composition with efficacy of sleep improvement and preparation method
  • Traditional Chinese medicine composition with efficacy of sleep improvement and preparation method
  • Traditional Chinese medicine composition with efficacy of sleep improvement and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine composition for improving sleep and health care food, which is prepared from the following raw materials in parts by weight: 60g of jujube seed, 60g of rehmannia glutinosa, 30g of dogwood, 30g of yam, and 30g of motherwort.

[0022] The method that utilizes above-mentioned Chinese medicine composition to prepare health food is as follows:

[0023] Step (1), water decoction: Put jujube kernels, rehmannia glutinosa, dogwood, yam, and motherwort into a decoction bag, add water and soak for 30 minutes, decoct twice, add 10 times the total weight of raw materials for decoction for the first time For 1 hour, add water 8 times the total weight of raw materials for the second time and decoct for 45 minutes, combine the two decoctions, squeeze the dregs, filter, and obtain decoction;

[0024] Step (2), concentrating and drying: heating and concentrating the water extract to an extract, freeze-drying at -40°C, and pulverizing to obtain a dry extract...

Embodiment 2

[0062] A traditional Chinese medicine composition for improving sleep health food, which is prepared from the following raw materials in parts by weight: 60g of jujube seed, 60g of rehmannia glutinosa, 40g of dogwood, 40g of yam, and 60g of motherwort.

[0063] The method that utilizes above-mentioned Chinese medicine composition to prepare health food is as follows:

[0064] Step (1), water decoction: Put jujube kernels, rehmannia glutinosa, dogwood, yam, and motherwort into a decoction bag, add water and soak for 30 minutes, decoct twice, add 10 times the total weight of raw materials for the first time and decoct For 1 hour, add water 8 times the total weight of raw materials for the second time and decoct for 45 minutes, combine the two decoctions, squeeze the dregs, filter, and obtain decoction;

[0065] Step (2), concentrating and drying: heating and concentrating the water extract to an extract, freeze-drying at -40°C, and pulverizing to obtain a dry extract powder;

...

Embodiment 3

[0103] Mice oral acute toxicity test (MTD):

[0104] 1. Animal source: Speifu (Beijing) Biotechnology Co., Ltd., KM mice, experimental animal quality certificate: No.11401500050054.

[0105] 2. Dose design: Select 40 Kunming mice of 18g~21g, half male and half male, to carry out the experiment. Animals had free access to food and water during the experiment. With a dosage of 20ml / kg BW, gavage 2 times with an interval of 6h, equivalent to 177.1g crude drug / kg BW (equivalent to 759 times the daily intake of the human body), observe continuously for 14 days, observe and record the general state of the animal, Body weight changes, signs of poisoning and death, etc., to determine the maximum tolerated dose (MTD).

[0106] 3. Way of giving samples: intragastric administration, the volume of intragastric administration is 20ml / kg BW.

[0107] 4. Test results

[0108] Mice of both genders were gavaged with test samples twice, with a dose of 177.1 g of crude drug / kg BW. During the...

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Abstract

The invention discloses a traditional Chinese medicine composition with an efficacy of sleep improvement. The traditional Chinese medicine composition is prepared from, by weight, 30-300 parts of semen ziziphi spinosae, 30-300 parts of radix rehmanniae preparata, 15-150 parts of fructus corni, 15-150 parts of rhizoma dioscoreae and 15-150 parts of herba leonuri. A preparation method includes steps: taking semen ziziphi spinosae, radix rehmanniae preparata, fructus corni, rhizoma dioscoreae and herba leonuri proportionally according to the formula, performing water decoction and extraction, and filtering; combining filtrates, and performing freeze drying and grinding to obtain water extract dry powder; jointly dissolving the dry powder and auxiliary materials into water to prepare health foods in different types and flavors. By formula selection according to traditional Chinese dietary therapy theories and clinical experience, functional components are extracted by water decoction according to a traditional extraction method, functional foods capable of effectively improving sleep can be provided, and by compatible utilization, a function of sleep improvement is achieved, safety and effectiveness are realized, no toxic and side effect is caused in long-term consumption, and accordingly long-term consumption is allowed.

Description

technical field [0001] The invention belongs to the technical field of health food, and in particular relates to a traditional Chinese medicine composition with the function of improving sleep and a method for preparing health food using the composition. Background technique [0002] Sleep is the most important and basic physiological activity of human beings. Sufficient and high-quality sleep is necessary for human beings. Sleep accounts for about one-third of the time in a person's life. Good sleep is the main symbol of physical and mental health and the basic physiological needs of human beings. Sleep can eliminate fatigue and restore physical strength; protect the brain and restore energy; enhance immunity and restore the body; promote growth; delay aging; protect mental health and skin beauty. However, with the rapid development of China's economy, the cost of living has gradually increased, and social competition has become increasingly fierce. People are under increa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P25/20A23L33/105A23C9/152
CPCA23C9/152A23C2240/15A23V2002/00A61K36/40A61K36/533A61K36/725A61K36/804A61K36/8945A23L33/105A61P25/20A61K2300/00A23V2200/30A23V2200/326A23V2200/31A23V2250/21
Inventor 赵思俊曲萍施怀生张蕻贺程蓓郭景文泰刚王婷婷李琛张俊凤张弥行江水李洋杨志敏
Owner SHANXI PROVINCE FOOD & DRUG INSPECTION INST
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