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Stable sterilizing solution for clinic

A sterilization, solution technology, applied in the direction of chemicals, disinfectants, bactericides for biological control, etc., can solve the problems of increasing solution corrosion, skin corrosion, easy decomposition, etc., to reduce unstable factors and improve sterilization. Active, avoid serious pollution effect

Active Publication Date: 2019-09-06
广州泰道安医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sodium hypochlorite disinfectant that exists on the market generally has some defects: on the one hand, because the hypochlorous acid in the solution has strong oxidizing and bleaching powers, it is easy to cause corrosion to the skin, causing the sodium hypochlorite solution to not be directly used clinically; On the one hand, due to the poor stability and easy decomposition of sodium hypochlorite itself, it has brought great difficulties and losses to its production, storage, transportation, sales and use.
Publication number CN1247707 adopts sodium alkylsulfonate, sodium alkylbenzenesulfonate, sodium hydroxide to improve the stability of sodium hypochlorite; but because it requires solution pH ≥ 12, greatly reduces the bactericidal activity of sodium hypochlorite, also improves the corrosion of solution At the same time, because sodium hypochlorite has strong oxidizing and bleaching properties, it cannot be used clinically
Publication No. CN102696675A describes a method of using amine oxide and organic phosphonic acid to improve the bactericidal activity of sodium hypochlorite solution, but does not provide a method for solving the environmental impact of phosphorus addition; and this technical solution is also not suitable for clinical and skin disinfection

Method used

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  • Stable sterilizing solution for clinic
  • Stable sterilizing solution for clinic
  • Stable sterilizing solution for clinic

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0044] S1. Add 1Kg of sodium chloride, 3g of boron nitride and 100g of mannitol into 99.49L of water and stir evenly, then add 0.1L of food-grade sodium hypochlorite solution with an available chlorine concentration of 10%, and mix thoroughly to obtain solution A;

[0045] S2. Slowly add 0.5Kg of dodecyldimethylamine oxide and 0.1Kg of glycerin to solution A in turn, stir while adding, and mix well;

[0046] S3. Finally, slowly add 5M hydrochloric acid, monitor the pH value of the entire solution system in real time during the addition process, stop adding when the pH value of the entire solution system is 5.8-6.5, and stir for another 30 minutes;

[0047] S4. The final solution is tested for pH, available chlorine concentration, and clarity, and subpackaged and packaged after passing the test.

preparation Embodiment 2

[0049] S1. Add 3Kg of sodium chloride, 8g of boron nitride and 500g of mannitol into 99.48L of water and stir evenly, then add 0.2L of food-grade sodium hypochlorite solution with an available chlorine concentration of 10%, and mix thoroughly to obtain solution A;

[0050] S2. Slowly add 3Kg of dodecyl dimethyl amine oxide and 2Kg of glycerin successively to solution A, stir while adding, and mix well;

[0051] S3. Finally, slowly add 5M hydrochloric acid, monitor the pH value of the entire solution system in real time during the addition process, stop adding when the pH value of the entire solution system is 5.8-6.5, and stir for another 30 minutes;

[0052] S4. The final solution is tested for pH, available chlorine concentration, and clarity, and subpackaged and packaged after passing the test.

preparation Embodiment 3

[0054] S1. Add 2Kg of sodium chloride, 5g of boron nitride and 300g of mannitol into 99.68L of water and stir evenly, then add 0.15L of food-grade sodium hypochlorite solution with an available chlorine concentration of 10%, and mix thoroughly to obtain solution A;

[0055] S2. Slowly add 2Kg of dodecyl dimethyl amine oxide and 1Kg of glycerin to solution A in turn, stir while adding, and mix well;

[0056] S3. Finally, slowly add 5M hydrochloric acid, monitor the pH value of the entire solution system in real time during the addition process, stop adding when the pH value of the entire solution system is 5.8-6.5, and stir for another 30 minutes;

[0057] S4. The final solution is tested for pH, available chlorine concentration, and clarity, and subpackaged and packaged after passing the test.

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Abstract

The invention discloses a stable sterilizing solution for clinic. The stable sterilizing solution for clinic comprises the following components in percentages by weight: 1.0-3.0% of sodium chloride, 0.003-0.008% of boron nitride, 0.1-0.2% of a sodium hypochlorite solution, 0.001-5.0% of a pH regulator, 0.5-3.0% of dodecyl dimethyl amine oxide, 0.1-0.5% of mannitol, 0.1-2.0% of glycerol and the balance of water, wherein the weight percentages of the components are based on the total weight of the sterilizing solution; and the pH value of the sterilizing solution is in the range of 5.0-6.5. Thesterilizing solution is long in shelf life and basically not corrosive, and is suitable for skin sterilization and clinical application. The stable sterilizing solution for clinic can be used for directly cleaning affected parts, plays a role in cleaning and disinfecting, meanwhile can be added into a spraying device for use, and sterilizes the environment.

Description

technical field [0001] The invention relates to the technical field of disinfection, in particular to a clinically stable sterilizing and disinfecting solution and a preparation method thereof, and also relates to applications of the sterilizing and disinfecting solution. Background technique [0002] Chlorine-containing disinfectants are currently one of the most commonly used effective fungicides, and their active ingredients are hypochlorous acid or hypochlorites. According to research by the U.S. Environmental Protection Agency, the bactericidal ability of hypochlorous acid under the same conditions is tens to hundreds of times that of hypochlorites. In fact, people have discovered that hypochlorous acid has a strong bactericidal effect as early as more than 100 years ago. Hypochlorous acid is a very weak acid, and it only exists in solution and has strong oxidizing properties. At the same time, hypochlorous acid solution has high safety for human and animal bodies. Aft...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61K9/08A61K47/04A61K47/02A61K47/18A61K47/10A61K47/26A61P17/02A61P17/00A01N59/00A01N33/24A01N25/22A01P3/00A01P1/00
CPCA01N25/22A01N33/24A01N59/00A61K9/0014A61K9/08A61K33/00A61K47/02A61K47/10A61K47/18A61K47/26A61P17/00A61P17/02
Inventor 司朝辉林洁琴
Owner 广州泰道安医疗科技有限公司
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