Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of preparation method of cranial neurotrophic treatment composition

A therapeutic composition and cranial nerve technology, applied in the field of oil synthesis, can solve the problems of untimely energy supply, slow metabolism of long-chain fatty acids, increased burden, etc., reduce energy and time consumption, simple preparation process, and low price The effect of time-consuming and energy-consuming

Active Publication Date: 2021-03-19
河北康睿达脂质有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention needs to consume a large amount of alkaline water and adsorbents in the process of deacidification, deodorization, etc. The consumption of such substances and subsequent treatment have increased the burden on the process.
[0004] In view of the slow metabolism of long-chain fatty acids in the body, the energy supply is not timely, and cannot satisfy special patients. Medium-chain fatty acids cannot provide essential fatty acids for the human body. Rapid oxidation in the liver will cause the concentration of ketone bodies in the body to rise suddenly, which is not good for diabetic patients. It will cause problems such as poisoning and complex preparation process of medium and long-chain fatty acids, large consumption of deacidification and deodorization, and subsequent treatment burden. It is necessary to find a preparation method of lipid composition, which makes the method simple, convenient and cheap, and at the same time The prepared lipid composition can be quickly metabolized in the human body, and can meet the nutritional needs of patients with different conditions of cranial nerves

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of preparation method of cranial neurotrophic treatment composition
  • A kind of preparation method of cranial neurotrophic treatment composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A preparation method of a brain neurotrophic treatment composition: adding fatty acid triglycerides, conjugated linoleic acid glycerides and β-sitosterol to a lipase collecting machine equipped with 435 lipase, IM lipase and DF15 lipase The transesterification reaction is carried out in the closed reactor of the device, the reaction temperature is 40° C., and the reaction time is 15 hours. Among them, fatty acid triglycerides are 8-10 carbon fatty acid triglycerides extracted from palm kernel oil and 16-24 carbon fatty acid triglycerides extracted from linseed oil, 8-10 carbon fatty acid triglycerides, 16- The weight ratio of 24 carbon fatty acid triglycerides, conjugated linoleic acid glycerides and β-sitosterol is 15:16:2:4; the addition of 435 lipase is 1.5% of the total weight of fatty acid triglycerides %, the addition of IM lipase is 0.6% of the total weight of fatty acid triglycerides, and the addition of DF15 lipase is 0.2% of the total weight of fatty acid trig...

Embodiment 2

[0024] A preparation method of a brain neurotrophic treatment composition: adding fatty acid triglycerides, conjugated linoleic acid glycerides and stigmasterol to a lipase collecting device equipped with 435 lipase, IM lipase and DF15 lipase The transesterification reaction was carried out in a closed reactor, the reaction temperature was 60° C., and the reaction time was 12 hours. Among them, fatty acid triglycerides are 8-10 carbon fatty acid triglycerides extracted from coconut oil and 16-24 carbon fatty acid triglycerides extracted from salamander oil, 8-10 carbon fatty acid triglycerides, 16-24 carbon fatty acid triglycerides The weight ratio of fatty acid triglycerides, conjugated linoleic acid glycerides and stigmasterol is 65:75:12:10; the addition of 435 lipase is 7% of the total weight of fatty acid triglycerides, IM fat The added amount of the enzyme is 1% of the total weight of the fatty acid triglyceride, and the added amount of the DF15 lipase is 2% of the total...

Embodiment 3

[0026] A preparation method of a brain neurotrophic treatment composition: adding fatty acid triglycerides, conjugated linoleic acid glycerides and campesterol to a lipase collecting device equipped with 435 lipase, IM lipase and DF15 lipase The transesterification reaction was carried out in a closed reactor, the reaction temperature was 55° C., and the reaction time was 13.5 hours. Among them, the fatty acid triglycerides are 8-10 carbon fatty acid triglycerides extracted from palm kernel oil and 16-16-carbon fatty acid triglycerides extracted from garlic oil, sorbifolia oil and linseed oil with a weight ratio of 1:1:2. The weight ratio of 24-carbon fatty acid triglyceride, 8-10 carbon fatty acid triglyceride, 16-24 carbon fatty acid triglyceride, conjugated linoleic acid glyceride and campesterol is 34:42:8:6 ; The addition of 435 lipase is 4.5% of the total weight of fatty acid triglycerides, the addition of IM lipase is 2% of the total weight of fatty acid triglycerides, ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle size (mesh)aaaaaaaaaa
Login to View More

Abstract

The present invention provides a preparation method of a cerebral nerve nutritional therapeutic composition and relates to the field of synthesis of oils and fats. Fatty acid triglyceride, conjugatedlinoleic acid glyceride and phytosterol are used as raw materials, the raw materials are subjected to transesterification with 435 lipase, IM lipase and DF15 lipase, cooling, decolorization, deodorization, distillation and fine-filtration are conducted, then emulsification, embedding and spray-drying are conducted to obtain dry powder, then the dry powder is mixed with phosphatidylserine, N-acetylneuraminic acid, beta-hydroxy-beta-methylbutyrate calcium, konjac glucomannan, a mangosteen extract, elderberries and yeast beta-glucan, and homogenizing is conducted to obtain the medium-long chain structure lipid composition. The technology is simple, convenient and inexpensive, and can produce precise nutritional composition suitable for clinical rehabilitation of diseases of stroke, Alzheimer's disease, depression, Parkinson's disease, epilepsy, etc.

Description

technical field [0001] The invention relates to the field of oil synthesis, in particular to a preparation method of a brain neurotrophic treatment composition. Background technique [0002] Alzheimer's disease is a progressive neurodegenerative disease with insidious onset. According to statistics, in 2010, the number of people suffering from Alzheimer's disease in the world has reached 35.6 million, with an average of one new Alzheimer's patient every 7 seconds. Chinese Alzheimer's patients account for 1 / 4 of the total number of cases in the world. , with an average annual increase of 300,000 new cases. The cost of care for an Alzheimer's patient is 14 times that of a cancer patient, and there is no cure for it through drugs, and prevention is still the best way. Stroke is a group of diseases caused by the sudden rupture of blood vessels in the brain or the inability of blood to flow into the brain due to vascular blockage, which causes brain tissue damage. Usually, the ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/661A61K31/198A61K31/19A61K31/736A61K31/716A61K31/22A61K36/38A61P25/28A61P9/10A61P25/24A61P25/16A61P25/08
CPCA61K31/19A61K31/198A61K31/22A61K31/661A61K31/716A61K31/736A61K36/38A61P9/10A61P25/08A61P25/16A61P25/24A61P25/28A61K2300/00
Inventor 苑海鹏苑海祥刘宝华王延荣苑洪德刘宪军来创业
Owner 河北康睿达脂质有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com