Medical degradable high molecular antibacterial composite material

A composite material and polymer technology, which is applied in the field of degradable polymer medical materials, can solve the problems of resistance to tensile strength and other problems, achieve the effect of no allergic reaction, effective degradation, and guaranteed performance

Inactive Publication Date: 2019-06-14
亳州科蔚科技服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem that the tensile strength of the existing medical tablecloth will be affected after disinfection, and to provide a medical degradable polymer antibacterial composite material

Method used

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  • Medical degradable high molecular antibacterial composite material
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preparation example Construction

[0020] The preparation method of the biomass extract is as follows: soak mint dry powder in pepper water for 6-8 hours, then dry at a temperature of 60°C until the water content is lower than 5%, to obtain the extract A; then summer Wash the dried ears of subtilis subtilis, crush them through a 120-mesh sieve after drying, then mix them with ethanol solution with a mass concentration of 75-85% at a weight ratio of 1:4-6, and ultrasonicate for 60 minutes at a temperature of 35-45°C After suction filtration, ultrasonic treatment at 45°C for 1.5 hours, suction filtration, rotary evaporation and concentration at 50°C, and freeze-drying to obtain extract material B; extract material A and extract material B were mixed at a weight ratio of 2:1 to obtain raw material extract.

[0021] As can be seen from the above description, the extract A prepared by mint dry powder can effectively improve the antibacterial performance of the composite material, but it will affect the temperature r...

Embodiment 1

[0033]A medical degradable polymer antibacterial composite material, comprising the following raw materials in parts by weight: 55 parts of polytrimethylene glutarate with an intrinsic viscosity of 1.138dL / g, 2 parts of dimethylchlorosilane, 3-(2-pyridyl 5 parts of dithio)propionic acid N-hydroxysuccinimide ester, 11 parts of hydroxyl compound, 1 part of royal acid, 1.5 parts of toughening agent, 14 parts of biomass extract;

[0034] The preparation method of the biomass extraction material is as follows: soak the dry peppermint powder in pepper water for 7 hours, and then dry it at a temperature of 60°C until the water content is lower than 5%, to obtain the extraction material A; then the Prunella vulgaris Wash the dried fruit ears, crush them through a 120-mesh sieve after drying, and then mix them with an ethanol solution with a mass concentration of 80% at a weight ratio of 1:5. Under the condition of sonication for 1.5 hours, suction filtration, concentrated by rotary ev...

Embodiment 2

[0038] A medical degradable polymer antibacterial composite material, comprising the following raw materials in parts by weight: 50 parts of polytrimethylene glutarate with an intrinsic viscosity of 1.138dL / g, 3 parts of dimethylchlorosilane, 3-(2-pyridyl 7 parts of dithio)propionic acid N-hydroxysuccinimide ester, 7 parts of hydroxyl compound, 0.6 part of royal acid, 2 parts of toughening agent, 16 parts of biomass extract;

[0039] The preparation method of the biomass extract is as follows: soak the dry peppermint powder in pepper water for 8 hours, and then dry it at a temperature of 60°C until the water content is lower than 5%, so as to obtain the extract A; then the Prunella vulgaris Wash the dried fruit ears, crush them through a 120-mesh sieve after drying, and then mix them with an ethanol solution with a mass concentration of 85% at a weight ratio of 1:4. Under the condition of sonication for 1.5 hours, suction filtration, concentrated by rotary evaporation at 50°C,...

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Abstract

The invention belongs to the technical field of a degradable high molecular medical material, and particularly relates to a medical degradable high molecular antibacterial composite material. The medical degradable high molecular antibacterial composite material is prepared from the following raw materials of polypropylene glycol glutarate with the intrinsic viscosity being 1.138dL / g, dimethylchlorosilane, 3-(2-pyridine disulfide) propanoic acid N-hydroxysuccinimide eater, hydroxyl compound, royal jelly acid, toughening agents and biomass extracting materials. Compared with the prior art, themedical degradable high molecular antibacterial composite material has the following advantages that through the addition of an extraction material A, the cooperated effect can be achieved with royaljelly; the antibacterial performance of the composite material can be improved; certain temperature resistance is ensured; through the reasonable matching with other raw materials, the stretching resistant performance with the composite material is ensured; the royal jelly can improve the toughness of the composite materials; the use performance of medical tablecloth is further ensured; meanwhile,the effective degradation can be realized; the environment pollution is avoided; the obtained polyester polymer materials are sterile and do not have heating sources; the hemolysis ratio is smaller than 5 percent; no anaphylactic reaction exists; no genetic toxicity exists; the safe use is realized.

Description

technical field [0001] The invention belongs to the technical field of degradable polymer medical materials, and in particular relates to a medical degradable polymer antibacterial composite material. Background technique [0002] The development of medical polymer material products in China started relatively late. Products such as disposable infusion sets, syringes and plastic blood bags were only developed in the 1970s. At present, materials such as polypropylene are generally used as base materials for disposable syringes. Such syringes cannot be used after being discarded. Self-degradation, polluting the environment, and endangering people's health. The usual centralized incineration and destruction method not only cannot realize resource recycling, but also aggravates environmental pollution. Driven by interests, discarded syringes are illegally reused by criminals, which will cause cross-fertilization. Infection and other medical risks. [0003] During the operation,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L67/02C08L47/00C08L73/02C08L71/00C08L67/00C08K5/09C08K5/00
Inventor 余国海
Owner 亳州科蔚科技服务有限公司
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