Pharmaceutical composition for invigorating liver and eliminating lipid as well as preparation method, preparation and application thereof

A composition and fat-reducing technology, applied in the field of medicine, can solve problems such as endangering public health and lack of treatment options, and achieve the effects of improving the symptoms of Qi stagnation and blood stasis, inhibiting lipid peroxidation damage, and reducing deposition

Inactive Publication Date: 2019-04-09
云南省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

NAFLD has become an increasingly important cause of chronic liver disease and seriously endangers public health, but there is still a lack of ideal treatment options

Method used

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  • Pharmaceutical composition for invigorating liver and eliminating lipid as well as preparation method, preparation and application thereof
  • Pharmaceutical composition for invigorating liver and eliminating lipid as well as preparation method, preparation and application thereof
  • Pharmaceutical composition for invigorating liver and eliminating lipid as well as preparation method, preparation and application thereof

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preparation example Construction

[0036] The preparation method of the pharmaceutical composition for invigorating the liver and eliminating fat of the present invention comprises the steps of pretreatment, crushing of notoginseng, extraction of volatile oil, inclusion of volatile oil, extraction and mixing of water-soluble extract, and specifically includes:

[0037] A. Pre-processing:

[0038] Selected medicinal materials to remove impurities;

[0039] B. Panax notoginseng crushed

[0040] Take the selected Panax notoginseng, dry below 80°C, crush, sieve, weigh according to the weight required by the formula, and obtain Panax notoginseng powder a;

[0041] C. Extraction of volatile oil

[0042] Mix the curcuma, turmeric and green bark of the selected formula ratio, add water 2-5 times the total weight of the curcuma, turmeric and green bark, and extract by steam distillation to obtain volatile oil b, extract c and medicinal dregs d;

[0043] D. Inclusion of volatile oil

[0044] (1) Take the volatile oil...

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Abstract

The invention discloses a pharmaceutical composition for invigorating liver and eliminating lipid as well as a preparation method, preparation and application thereof. The pharmaceutical composition for invigorating liver and eliminating lipid comprises the following raw materials in parts by weight: 10-20 parts of radix salviae miltiorrhizae, 3-7 parts of radix notoginseng, 10-20 parts of rhizomazedoariae, 12-30 parts of fructus crataegi, 12-30 parts of radix astragali, 5-15 parts of pericarpium citri reticulatae viride, 10-20 parts of radix paeoniae rubra, 10-20 parts of rhizoma curcumae longae, 10-20 parts of rhizoma alismatis, 10-20 parts of flos chrysanthemi, 10-20 parts of folium nelumbinis and 5-15 parts of radix glycyrrhizae; the preparation obtained by steps of pretreatment, radix notoginseng crushing, volatile oil inclusion, water-soluble extract extraction and mixing can be a soup, a pill, a granule, a tablet, a capsule, a mixture or other clinically appropriate dosage forms prepared by adding pharmaceutically acceptable excipients into the pharmaceutical composition for invigorating liver and eliminating lipid; and the application is application of the pharmaceutical composition for invigorating liver and eliminating lipid to preparation of medicines for preventing / treating non-alcoholic fatty liver. The pharmaceutical composition provided by the invention can significantly reduce deposition of blood lipids in the liver and improve the liver function to prevent and treat non-alcoholic fatty liver.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for invigorating the liver and reducing fat, as well as its preparation method, preparation and application. Background technique [0002] According to its onset characteristics and clinical manifestations, traditional Chinese medicine classifies nonalcoholic fatty liver disease into the categories of hypochondriac pain, fullness, turbid phlegm, and liver addiction. Traditional Chinese medicine believes that the pathogenesis of nonalcoholic fatty liver disease is related to phlegm, dampness, and blood stasis, and turbid phlegm and blood stasis play a key role in the occurrence and development of this disease. Phlegm turbidity and blood stasis can cause phlegm and blood stasis to intertwine or phlegm and blood stasis to intersect, just as it is said in "On the Origin and Symptoms of All Diseases: Phlegm-retention Diseases of the Dynasties"...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K47/69A61P1/16A61P3/06
CPCA61K36/258A61K36/287A61K36/481A61K36/484A61K36/537A61K36/62A61K36/65A61K36/71A61K36/734A61K36/752A61K36/884A61K36/9066A61K2236/331A61K2236/37A61K47/6951A61P1/16A61P3/06A61K2300/00
Inventor 温伟波
Owner 云南省中医医院
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