Radix bupleuri and cassia twig oral liquid and preparation method thereof

Abstract

The invention belongs to the technical field of veterinary medicines, and discloses radix bupleuri and cassia twig oral liquid and a preparation method thereof. The radix bupleuri and cassia twig oralliquid is prepared from the following crude medicines in percentage by weight of 20-40% of radix bupleuri, 10-30% of radix scutellariae, 10-20% of herba ephedrae, 5-20% of echinacea purpurea, 5-20% of radix trichosanthis, 5-20% of cassia twigs, 5-20% of dried ginger, 5-10% of oyster and 5-10% of radix glycyrrhizae preparata. The preparation method comprises the following steps of taking the crudemedicines in proportion, and preparing the taken crude medicines into coarse powder; adding water to 3 kinds of crude medicine coarse powder of the radix bupleuri, the cassia twigs and the dried ginger, performing distillation, collecting volatile oil for standby application, and filtering an aqueous solution obtained through distillation so as to obtain decoction dregs and distillation remainingliquid; adding water to the obtained decoction dregs and surplus other crude medicine coarse powder, performing ultrasonic decoction, performing filtration after decoction, taking filtrate, combiningthe taken filtrate with the distillation remaining liquid, performing membrane separation so as to obtain clear liquid, and further concentrating the clear liquid so as to obtain concentrated liquidof which the relative density is 1.15-1.20 at 50 DEG C; and adding polysorbate 80 of which the constant volume weight is 1-2% to the volatile oil, after dissolving to obtain a solution, adding the solution to the concentrated liquid, then adding a preservative, making the volume constant with water until the weight of a mixture is 1-2 times of the total weight of the crude medicines, performing uniform stirring, performing filtration, and performing filling so as to obtain the radix bupleuri and cassia twig oral liquid. The oral liquid disclosed by the invention is reasonable in prescription and high in absorption rate.

Description

technical field [0001] The invention belongs to the technical field of veterinary drugs, and in particular relates to a chaigui oral liquid and a preparation method thereof. Background technique [0002] The chicken body feels the external pathogens of wind and cold, first there are symptoms such as fever and chills, coughing and runny nose due to lung failure, at this time, according to the situation of the large group, the medicine for reconciling and dispelling cold can quickly recover; if it is not timely and appropriate Treatment, if the disease continues to develop, it will lead to the pathogenic heat of the stagnant exterior entering the interior, causing fever, decreased material, cough and asthma, sticky phlegm, increased yellow-green stool, sepsis, and even air sacculitis, peritonitis, bronchial blockage, etc. At this time, whether it is a high drug fee or a dead pan, it will bring a lot of economic losses to the breeder. [0003] In current clinical practice, the...

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Problems solved by technology

[0002] The chicken body feels the external pathogens of wind and cold, first there are symptoms such as fever and chills, coughing and runny nose due to lung failure, at this time, according to the situation of the large group, the medicine for reconciling and dispelling cold can quickly recover; if it is not timely and appropriate Treatment, if the disease continues to develop, it will lead to the pathogenic heat of the stagnant exterior entering the interior, causing fever, decreased material, cough and asthma, sticky phlegm, increased yellow-green stool, sepsis, and even air sacculitis, peritonitis, bronchial blockage, etc. At this time, whether it is high drug costs or dead shopping, it will bring a lot of economic losses to the breeders.

[0003] In current clinical practice, the use of chemical antibacterial and anti-inflammatory drugs for the above symptoms has poor curative effect, and it is easy to cause repeated illness, and even protracted and aggravated illness; in clinical practice, there are very few existing Chinese veterinary medicine products that can effectively prevent and treat this kind of cold In clinical practice, Jingfangbaidu powder has poor medication convenience and is not suitable for mixed drink administration, and is limited by gastrointestinal fluid infiltration, dissolution rate and dissolution rate after oral administration, which affects the body's absorption and poor bioavailability, which limits product application

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