Buccal tablet with effect of relieving discomfort of oral cavity and throat and preparation method thereof

A technology for throat and discomfort, which is applied in lozenges and preparations for relieving oral and throat discomfort. It can solve the problems of difficult product taste, poor consumer experience, and poor taste, so as to improve the compliance of taking, enhance the Cooling feeling, guaranteed curative effect

Active Publication Date: 2019-03-19
GUANGDONG YIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing Baiyao decoction products with the effect of clearing the throat and sharpening the throat are sour and difficult to swallow, with poor taste and poor consumer experience; even though the product has a certain curative effect, it is difficult to achieve oral ulcers, chronic pharyngitis and other patients who need long-term medication conditioning Demand for product taste

Method used

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  • Buccal tablet with effect of relieving discomfort of oral cavity and throat and preparation method thereof
  • Buccal tablet with effect of relieving discomfort of oral cavity and throat and preparation method thereof
  • Buccal tablet with effect of relieving discomfort of oral cavity and throat and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Raw material ratio:

[0049] 12.5 parts of Baiyaojian, 10 parts of mint, 20.5 parts of microcrystalline cellulose, 35 parts of sucrose powder, 27.6 parts of mannitol, 4 parts of sodium carboxymethyl starch, 0.8 parts of starch, 0.2 parts of sucralose, 0.2 parts of mint essence , 0.05 parts of jasmine essence, 0.5 parts of magnesium stearate, and 0.1 parts of menthol.

[0050] Its preparation process comprises the following steps:

[0051] a) Take peppermint, wash it, dry it at a low temperature below 50°C, crush it into 40-60 mesh powder, extract it with supercritical carbon dioxide to obtain peppermint oil, and set aside; take Baiyao decoction, remove impurities, and set aside.

[0052] b) Take mint extracted by supercritical carbon dioxide, add Baiyao decoction, add water to extract twice, add 8 times the amount of water for the first time, decoct for 30 minutes, add 6 times the amount of water for the second time, decoct for 30 minutes, filter After that, the combi...

Embodiment 2

[0059] Raw material ratio:

[0060] 10 parts of Baiyaojian, 20 parts of mint, 39 parts of microcrystalline cellulose, 20 parts of sucrose powder, 25 parts of mannitol, 3 parts of sodium carboxymethyl starch, 1 part of starch, 0.19 parts of sucralose, 0.25 parts of mint essence , 0.1 part of jasmine essence, 0.8 part of magnesium stearate, and 0.08 part of menthol.

[0061] Its preparation process comprises the following steps:

[0062] a) Take peppermint, wash it, dry it at a low temperature below 50°C, crush it into 40-60 mesh powder, extract it with supercritical carbon dioxide to obtain peppermint oil, and set aside; take Baiyao decoction, remove impurities, and set aside.

[0063] b) Take mint after supercritical carbon dioxide extraction, add Baiyao decoction, add water to extract twice, add 7 times the amount of water for the first time, decoct for 25 minutes, add 7 times the amount of water for the second time, decoct for 25 minutes, filter After that, the combined fi...

Embodiment 3

[0070] Raw material ratio:

[0071] 17 parts of Baiyaojian, 5 parts of mint, 24 parts of microcrystalline cellulose, 40 parts of sucrose powder, 15 parts of mannitol, 5 parts of sodium carboxymethyl starch, 0.9 parts of starch, 0.22 parts of sucralose, 0.3 parts of mint essence , 0.08 parts of jasmine essence, 1 part of magnesium stearate, and 0.1 part of menthol.

[0072] Its preparation process comprises the following steps:

[0073] a) Take peppermint, wash it, dry it at a low temperature below 50°C, crush it into 40-60 mesh powder, extract it with supercritical carbon dioxide to obtain peppermint oil, and set aside; take Baiyao decoction, remove impurities, and set aside.

[0074] b) Take mint extracted by supercritical carbon dioxide, add Baiyao decoction, add water to extract twice, add 8 times the amount of water for the first time, decoct for 30 minutes, add 7 times the amount of water for the second time, decoct for 20 minutes, filter After that, the combined filtra...

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Abstract

The invention discloses a buccal tablet with an effect of relieving discomfort of oral cavity and throat and a preparation method thereof. The buccal tablet is prepared from the following raw materials in parts by weight: 10-20 parts of fermented gallnut and tea, 5-20 parts of peppermint, 10-40 parts of microcrystalline cellulose, 30-95 parts of a sweetening agent, 2-8 parts of sodium carboxymethyl starch, 0.5-1.5 parts of starch, 0.2-0.6 part of cooling additives and 0.1-1.0 part of magnesium stearate. According to the preparation method, the fermented gallnut and tea and the peppermint witheffects of clearing and nourishing sore-throat are combined, and the additives are screened, so that the defect of sore taste of the fermented gallnut and tea can be overcome, and the buccal tablet has cool and refreshing taste and unique flavor, has good effects of relieving discomfort of oral cavity and throat, is a product with both effects and taste for clearing sore-throat, and can achieve the aims of soothing oral cavity and sore-throat and other chronic symptoms if being taken for a long time.

Description

technical field [0001] The invention relates to the field of tablets, in particular to a buccal tablet for relieving discomfort in the mouth and throat and a preparation method thereof. Background technique [0002] Lozenges are tablets that dissolve slowly in the mouth for local or systemic action. The raw materials in buccal tablets are generally soluble, and mainly play local anti-inflammatory, sterilizing, astringent, analgesic or local anesthetic functions. [0003] With the rapid development of social economy, the acceleration of the pace of life, the increase of psychological pressure, the pollution of the natural environment, etc., lead to the widespread occurrence of "modern civilization diseases" such as oral ulcers and throat discomfort. Baiyaojian is mainly used for lung heat cough, wind-fire toothache, tongue erosion and other diseases, and is very suitable for improving oral ulcers and throat discomfort. At present, there are some heat-clearing and throat-cle...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K36/82A61K9/20A61K47/26A61K47/10A61P1/02A61P11/04A61K35/64
CPCA61K9/0056A61K9/2013A61K9/2018A61K9/2059A61K35/64A61K36/534A61K36/82A61K2236/331A61K2236/37A61K2236/53A61P1/02A61P11/04A61K2300/00
Inventor 罗汝锋罗艳萍曹亚兰蓝泽基罗锦杰罗进
Owner GUANGDONG YIFANG PHARMA
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