A curcumin compound preparation for treating cancer

Abstract

The invention relates to a curcumin compound preparation for treating cancer. By using curcumin, pterostilbene and δ-tocotrienol as raw materials and carrying out a suitable weight ratio, the three components are synergistically The number of anti-cancer targets and the anti-cancer spectrum are superimposed, and the anti-cancer effect is significantly multiplied. The curcumin in the curcumin compound preparation of the present invention can kill cancer stem cells, and can significantly reduce the recurrence rate of cancer compared with conventional chemotherapy methods that cannot kill cancer stem cells. The invention is non-toxic to human body and will not produce adverse reactions when applied in large doses. And the treatment cost is expected to be less than half or lower than that of conventional chemotherapy drugs, and far lower than the high treatment cost of cellular immunotherapy CAR‑T, which has broad application prospects in the field of cancer treatment.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to a curcumin compound preparation for treating cancer. Background technique [0002] Cancer is a general term for a variety of diseases that can affect any part of the body. Other terms used are malignant tumor and neoplasm. A defining feature of cancer is the rapid production of abnormal cells that grow beyond their usual boundaries and can invade adjacent parts of the body and spread to other organs. This process is called metastasis, and metastasis is the leading cause of death from cancer. Cancer is currently one of the leading causes of death worldwide. WHO estimates that without intervention, 84 million people will die from cancer between 2005 and 2015. [0003] Cancer cells have the ability to grow and spread uncontrollably, it can affect almost any part of the body, and often invades surrounding tissue and can metastasize to other sites. Cancer is a leading cause of d...

AI Technical Summary

Problems solved by technology

[0005] 1) Because of its clinical application, conventional chemotherapy can only relieve cancer, but cannot cure cancer, and because it kills cancer cells and normal cells at the same time, it will cause serious adverse reactions during treatment, such as bone marrow function suppression, nausea, Gastrointestinal adverse reactions such as diarrhea and vomiting; reduced safety of the drug, and easy relapse after treatment due to inability to kill cancer stem cells

The cost of conventional chemotherapy generally costs tens of thousands to hundreds of thousands of yuan for a course of treatment;

[0006] 2) Targeted therapy: its curative effect is slightly better than conventional chemotherapy, but because it can only target 1-2 targets, it is difficult to cure cancer, and its advantage is that it can only prolong the life of patients by an average of several months compared with chemotherapy

In addition, although immunotherapy represented by PD-1 (programmed cell death-1) and PD-L1 (programmed death ligand-1) antibodies has good curative effect, it is limited to about 20% of cancer patients, so Its application is relatively limited, and the cost of targeted therapy is relatively high. Generally, a course of treatment also costs tens to hundreds of thousands of yuan;

[0007] 3) Chimeric antigen receptor T cell immunotherapy (CAR-T); although it is very popular because of its short-term curative effect, it also has its limitations, and recurrence can still be found if long-term follow-up

[0012] Cancer, like AIDS, is a very difficult disease to treat, and the treatment of difficult and miscellaneous diseases often requires extraordinary means and innovative breakthrough methods, relying only on traditional cancer treatment methods, and using one or two anticancer chemotherapy drugs. Most cannot effectively control or cure cancer

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