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Microencapsulated preparation for preventing and treating chicken leukocytopathy and preparation method

A technology for leukocyte and protozoal disease, which is applied in the field of microcapsule preparations for preventing and treating chicken leukocyte protozoa and its preparation, can solve the problems of uneven mixing, too little addition of pyrimethamine, etc., achieves smooth surface, enhances body Immunity, improve the effect of breeding efficiency

Inactive Publication Date: 2019-01-11
FOSHAN STANDARD BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Ordinary pyrimethamine premixes and granules often have uneven mixing due to the addition of too little pyrimethamine

Method used

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  • Microencapsulated preparation for preventing and treating chicken leukocytopathy and preparation method
  • Microencapsulated preparation for preventing and treating chicken leukocytopathy and preparation method
  • Microencapsulated preparation for preventing and treating chicken leukocytopathy and preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0034] A microcapsule preparation for preventing and treating chicken leukocyte protozoa disease, comprising the following components by weight:

[0035]

[0036]

[0037] A preparation method of a microencapsulated preparation for preventing and treating chicken leukocyte protozoa, comprising the following steps:

[0038] (1) take by weighing each component by weight;

[0039] (2) Tween 80 and Tween 20 are heated to 60 DEG C to melt, add pyrimethamine and astragalus polysaccharide, adopt a high-speed mixer with a rotating speed of 600r / min to stir for 1 hour to obtain a uniformly stirred emulsion;

[0040] (3) heating soluble starch, polyethylene glycol 4000, monoglyceride and stearic acid to a temperature of 80° C., adding in the emulsion of step (2), and stirring 1.5 batches at a high speed of 800 r / min using a rotating speed hours to obtain a uniform material;

[0041] (4) cooling the uniform material obtained in step (3) to 60 ° C, and granulating by a low-speed s...

Embodiment 2

[0044] A microcapsule preparation for preventing and treating chicken leukocyte protozoa disease, comprising the following components by weight:

[0045]

[0046] A preparation method of a microencapsulated preparation for preventing and treating chicken leukocyte protozoa, comprising the following steps:

[0047] (1) take by weighing each component by weight;

[0048] (2) Tween 80 and Tween 20 are heated to 60 DEG C to melt, add pyrimethamine and astragalus polysaccharide, adopt a high-speed mixer with a rotating speed of 600r / min to stir for 1 hour to obtain a uniformly stirred emulsion;

[0049] (3) heating soluble starch, polyethylene glycol 4000, monoglyceride and stearic acid to a temperature of 80° C., adding to the emulsion of step (2), and using a high-speed mixer with a rotating speed of 800 r / min to stir 1.5 hours to obtain a uniform material;

[0050] (4) cooling the uniform material obtained in step (3) to 60 ° C, and granulating by a low-speed spray granulator...

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Abstract

The invention discloses a microencapsulated preparation for preventing and treating chicken leukocytopathy, which comprises the following components in parts by weight: 0.1-2 parts of pyrimethamine, 1-10 parts of astragalus polysaccharide, 40-80 parts of carrier and 30-70 parts of emulsifier. The invention provides a microencapsulated preparation containing pyrimidine for preventing and treating chicken leukocytopathy, combined with Astragalus polysaccharide, which can enhance immunity and improve production performance of chicken, pyrimidine can effectively improve drug efficacy and reduce side effects of pyrimidine, so that the body can recover quickly after treatment.

Description

technical field [0001] The invention relates to the field of animal medicines, in particular to a microencapsulated preparation for preventing and treating chicken leukocytosis and a preparation method thereof. Background technique [0002] Chicken leukocytosis is an acute hematosporidiosis caused by a variety of leukocytosis of the genus Leukocytosis parasitizing the leukocytes and red blood cells of chickens. Due to the destruction of red blood cells and extensive hemorrhage, the chicken comb is pale, so it is also known as white crown disease. In recent years, the disease broke out in many areas of our country, and the harm to the chicken industry became more and more serious. Indigenous leukocytosis belongs to the phylum Protozoa, Phylum, Sporozoa, Hemosporidia, Plasmodium, and Leukocytosis. In my country, two species of Leukocytosis have been found in chickens: Leukocytoplasma carinii and Leukocytosis serratia. [0003] In clinical symptoms, infected chicks and reari...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K9/50A61K31/505A61P33/02
CPCA61K9/5063A61K9/5089A61K31/505A61K31/715A61P33/02A61K2300/00
Inventor 刘肖娟谭志坚黎剑坤翁亚彪符德文陈艺青袁增辉
Owner FOSHAN STANDARD BIO TECH
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