Medicine for treating osteomyelitis and preparation method thereof

Abstract

The invention discloses a medicine for treating osteomyelitis and a preparation method thereof. The medicine comprises the following raw materials in parts by weight: 1.0 to 20.0 parts of calcium hydroxide powder, 0.3 to 4.0 parts of antibiotics (one or two of cefoperazone, ceftazidime, cefamandole, imipenem, tobramycin, gentamicin and vancomycin), 1.0 to 20.0 parts of normal saline, and 0.1 to 3.0 parts of an iodophor solution. The adopted calcium hydroxide powder, antibiotics, normal saline and iodophor solution are medical grades. When in use, the raw materials are weighed according to theweight, mixed in an aseptic condition, sufficiently stirred, and prepared into paste. The paste is injected into osteomyelitis medullary canals subjected to debridement and blocked through bone cement, and wounds are sutured. The medicine has the advantages that the raw material the formula is simple, the raw materials are easy to get, the preparation method is simple, and convenient to operate, and the treatment effect is obvious.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a medicine for treating osteomyelitis and a preparation method thereof. Background technique [0002] With the advancement of science and technology, especially the rapid development of the transportation and construction industries, there have been many fractures caused by high-energy injuries, especially the cases of open fractures have increased sharply. Or post-fracture infection, traumatic osteomyelitis occurs. Traumatic osteomyelitis refers to bone infection caused by trauma (including open fractures, firearm injuries, and contamination during surgery, etc.), and is also a serious complication after limb trauma. , the treatment is difficult and the curative effect is poor, which can cause severe disability and dysfunction of the limbs, even amputation and life-threatening. [0003] Among the many treatment methods for chronic traumatic osteomyelitis, traditional lavage...

AI Technical Summary

Problems solved by technology

However, the current abuse of antibiotics has resulted in great drug resistance of pathogenic bacteria, which has greatly reduced the cure rate of traditional therapy for chronic traumatic osteomyelitis. Moreover, the most commonly used antibiotic-containing bone cement is single gentamicin, and its infection control rate is gradually decreasing