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Chinese-Western compound preparation for treating senile dementia and preparation method thereof

A technology for senile dementia and compound preparations, applied in the field of medicine, can solve the problems of inability to delay the development of the disease, liver and kidney toxicity of western medicine, and insignificant curative effect, and achieve the effects of low side effects, broad medical application prospects, and improvement of insomnia and forgetfulness

Inactive Publication Date: 2018-11-30
SHAANXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many western medicines for the treatment of senile dementia. These medicines can only temporarily alleviate the cognitive decline of patients, but cannot delay the development of the disease. Moreover, western medicines have serious adverse reactions such as liver and kidney toxicity, and are expensive.
In recent years, experts and scholars at home and abroad have begun to pay attention to natural traditional Chinese medicine. Traditional Chinese medicine has the advantages of strong long-term effect, strong drug resistance, safety and non-toxicity. Alzheimer's Drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A Chinese-Western compound preparation for treating senile dementia, which is compounded from Chinese medicine components and Western medicine components, and the Chinese medicine components are prepared from the following raw materials in parts by weight:

[0032] 10 parts of gastrodia elata, 10 parts of salvia miltiorrhiza, 10 parts of ginkgo biloba, 5 parts of acacia bark, 5 parts of Yizhi kernel, 2 parts of ebony plum, and 5 parts of earthworm;

[0033] Described western medicine is made up of following components:

[0034] 1 part of piracetamide, 1 part of donepezil hydrochloride, 1 part of vitamin B1.

Embodiment 2

[0036] A Chinese-Western compound preparation for treating senile dementia, which is compounded from Chinese medicine components and Western medicine components, and the Chinese medicine components are prepared from the following raw materials in parts by weight:

[0037] 20 parts of gastrodia elata, 15 parts of salvia miltiorrhiza, 15 parts of ginkgo biloba, 10 parts of acacia bark, 10 parts of Yizhi kernel, 5 parts of ebony plum, and 10 parts of earthworm;

[0038] 1.5 parts of piracetamide, 1.5 parts of donepezil hydrochloride, 1 part of vitamin B1.

Embodiment 3

[0040] A Chinese-Western compound preparation for treating senile dementia, which is compounded from Chinese medicine components and Western medicine components, and the Chinese medicine components are prepared from the following raw materials in parts by weight:

[0041] 15 parts of gastrodia elata, 12.5 parts of salvia miltiorrhiza, 12.5 parts of ginkgo biloba, 7.5 parts of acacia bark, 7.5 parts of Yizhi kernel, 3.5 parts of ebony plum, 7.5 parts of earthworm

[0042] Described western medicine is made up of following components:

[0043] 1.25 parts of piracetamide, 1.25 parts of donepezil hydrochloride, 0.75 parts of vitamin B1.

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Abstract

The invention discloses a Chinese-Western compound preparation for treating senile dementia and a preparation method thereof. The Chinese-Western compound preparation is formed by compounding traditional Chinese medicine components and Western medicine components. The traditional Chinese medicine components are prepared from the following raw materials in parts by weight: 10-20 parts of rhizoma gastrodiae, 10-15 parts of radix salviae miltiorrhizae, 10-15 parts of folium ginkgo, 5-10 parts of cortex albiziae, 5-10 parts of fructus alpiniae oxyphyllae, 2-5 parts of dark plum, and 5-10 parts oflumbricus; the western medicines are composed of the following components: 1-1.5 parts of piracetam, 1-1.5 parts of donepezil hydrochloride and 0.5-1 part of vitamin B1. The method of combining Chinese and Western medicines can effectively improve the circulation functions of brain nerves, brain blood vessels and brain blood circulation, improves and treats insomnia, amnesia, hypomnesia and cognitive decline caused by senile dementia, has the advantages of short course of treatment, quick effect and low side effects, and has broad medical application prospects.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a Chinese-Western compound preparation for treating senile dementia and a preparation method thereof. Background technique [0002] Alzheimer's disease can be divided into Alzheimer's disease (AD), vascular dementia (VD), mixed dementia (AD+VD) and other dementias. It is a persistent high-level neurological activity disorder, clinically manifested as deteriorating cognitive and memory functions, progressive decline in the ability of daily life, and various neuropsychiatric symptoms and behavioral disorders. Alzheimer's disease is a disease with a relatively high incidence rate. According to the World Health Organization, there are about 20 million elderly people suffering from Alzheimer's disease in the world. It is estimated that by 2020, there will be more than 30 million people with Alzheimer's disease worldwide. Therefore, the development of drugs to improve cognitive dysfunction and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61K9/48A61P25/28A61P25/20A61K31/4015A61K31/445A61K31/51A61K35/62
CPCA61K9/48A61K31/4015A61K31/445A61K31/51A61K35/62A61K36/16A61K36/48A61K36/537A61K36/736A61K36/8988A61K36/9062A61K2236/19A61K2236/331A61K2236/51A61K2236/53A61P25/20A61P25/28A61K2300/00
Inventor 苗琦张敏白永胜惠建荣王郁金贾妮
Owner SHAANXI UNIV OF CHINESE MEDICINE
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