A kind of method for preparing Chinese medicine broken wall decoction piece suspension

A technology of broken wall decoction pieces and suspension, applied in the directions of pharmaceutical formulation, liquid transportation, emulsion transportation, etc., can solve the problems of poor repeatability and unfavorable accurate measurement of particle size distribution of broken wall decoction pieces of traditional Chinese medicine, and achieve the effect of promoting dispersion.

Active Publication Date: 2020-11-06
JIANCHANGBANG CHINESE HERBAL MEDICINE CO LTD
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AI Technical Summary

Problems solved by technology

Solved the poor repeatability of the dispersion method for Chinese herbal decoction pieces in the prior art, which is not conducive to the accurate measurement of the particle size distribution of the broken Chinese herbal decoction pieces

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A method for preparing Poria cocos broken-wall decoction pieces suspension, comprising the following steps: weighing 0.2 g of Poria cocos-broken-wall decoction pieces in a beaker, adding 2 mL of absolute ethanol; stirring at 300 rpm / min, adding 298 mL of pure water rapidly; simultaneously turning on ultrasonic waves, 200w ultrasonic treatment for 0.5min. The resulting suspension was uniformly dispersed without large particles by visual inspection.

Embodiment 2

[0026] A method for preparing Poria cocos broken-wall decoction pieces suspension, comprising the following steps: taking 0.2 g of Poria cocos-broken-wall decoction pieces in a beaker, adding 15 mL of absolute ethanol; stirring at 500 rpm / min, adding 285 mL of pure water rapidly; simultaneously turning on the ultrasonic wave, 300w ultrasonic treatment for 1min. The resulting suspension was uniformly dispersed without large particles by visual inspection.

Embodiment 3

[0028] A method for preparing Poria cocos broken-wall decoction pieces suspension, comprising the following steps: weighing 0.2g Poria cocos-broken-wall decoction pieces in a beaker, adding 37.5mL of absolute ethanol; stirring at 700rpm / min, quickly adding 262.5mL of pure water; Ultrasound, 500w ultrasonic treatment for 2min. The resulting suspension was uniformly dispersed without large particles by visual inspection.

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PUM

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Abstract

The invention provides a method for preparing a traditional Chinese medicinal wall-broken decoction piece suspension. The suspension is used for measuring the particle size distribution of the traditional Chinese medicinal wall-broken decoction piece. The method specifically comprises the following steps: uniformly stirring the traditional Chinese medicinal wall-broken decoction piece and a solvent for mixing, thus obtaining a mixed solution A; adding pure water to the mixed solution A, and carrying out uniform stirring for obtaining a mixed solution B; and carrying out ultrasonic treatment onthe mixed solution B, thus obtaining the traditional Chinese medicinal wall-broken decoction piece suspension. According to the method, the solvent soluble with water and water are adopted as the dispersion media, meanwhile, the solvent soluble with water is added into the traditional Chinese medicinal wall-broken decoction piece first, pure water is then added, by utilizing the relatively strongintermolecular force generated during the mixing self-assembly process of the solvent and water, the dispersion of the traditional Chinese medicinal wall-broken decoction piece is promoted, and thusparticles of the prepared traditional Chinese medicinal wall-broken decoction piece suspension can be sufficiently dispersed. With the method provided by the invention, the problems that in the priorart, the traditional Chinese medicinal wall-broken decoction piece can not be well dispersed, and the repeatability is poor, are solved.

Description

Technical field: [0001] The invention belongs to the technical field of quality detection of traditional Chinese medicines, and in particular relates to a method for preparing a suspension of broken-wall decoction pieces of traditional Chinese medicines. Background technique: [0002] The wall-breaking technology of Chinese medicine decoction pieces is to crush Chinese medicine to the level of cell wall breaking, so as to promote the use of all components of Chinese medicine, and its medicinal material basis remains unchanged. [0003] Broken wall decoction pieces of traditional Chinese medicine use modern ultrafine pulverization technology to break the cell wall of Chinese medicinal materials to make wall-broken powder, and then use shape-forming technology to make full-ingredient granular decoction pieces. Ultrafine pulverization technology is a new technology developed rapidly in recent years. For example, most of the active ingredients in Chinese medicinal materials suc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/10A61K36/076A61K36/8988A61K36/64A61K36/488A61K36/71A61K36/65A61K36/41
CPCA61K9/10A61K36/076A61K36/41A61K36/488A61K36/64A61K36/65A61K36/71A61K36/8988
Inventor 田军易斌王曙宾罗丽莲肖艳皎刘娜魏长龙
Owner JIANCHANGBANG CHINESE HERBAL MEDICINE CO LTD
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