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Composition for promoting skin barrier repair and application thereof

A composition and the technology of aloe vera extract, which are applied in the field of biomedicine, can solve the problems of lack of pertinence in skin barrier repair, and achieve the effect of promoting skin barrier repair, strengthening repair function, and promoting repair

Inactive Publication Date: 2018-10-23
GUANGZHOU GUOYU MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These products or disclosed technical methods are not very specific for skin barrier repair

Method used

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  • Composition for promoting skin barrier repair and application thereof
  • Composition for promoting skin barrier repair and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A composition for promoting skin barrier repair, which comprises the following components in parts by weight: trehalose 10wt%, sodium hyaluronate 30wt%, centella asiatica extract 8wt%, spirulina polysaccharide 8wt%, collagen 10wt%, aloe vera Extract 20wt%, ceramide 5wt%, sodium polyglutamate 5wt%, ascorbyl glucoside 2wt%, acetylglucosamine 2wt%.

[0019] Wherein, the composition of sodium hyaluronate is: sodium hyaluronate with a molecular weight of 850k-1600kDa accounts for 60wt%, sodium hyaluronate with a molecular weight of 1800k-2500kDa accounts for 30wt%, and sodium hyaluronate with a molecular weight of 3k-10kDa accounts for 10wt%.

[0020] Among them, the molecular weight of collagen is less than 1kDa.

[0021] Among them, the aloe extract is desalted aloe gel powder, and its components are: desalted aloe gel powder with a molecular weight greater than or equal to 1000kDa accounts for 60wt%, desalted aloe gel powder with a molecular weight of 200kDa-1000kDa accou...

Embodiment 2

[0025] A composition for promoting skin barrier repair, which comprises the following components in parts by weight: 20wt% trehalose, 10wt% sodium hyaluronate, 15wt% centella asiatica extract, 15wt% spirulina polysaccharide, 12wt% collagen, aloe vera Extract 20wt%, ceramide 1wt%, sodium polyglutamate 3wt%, ascorbyl glucoside 2wt%, acetylglucosamine 2wt%.

[0026] Wherein, the composition of sodium hyaluronate is: sodium hyaluronate with a molecular weight of 850k-1600kDa accounts for 50wt%, sodium hyaluronate with a molecular weight of 1800k-2500kDa accounts for 30wt%, and sodium hyaluronate with a molecular weight of 3k-10kDa accounts for 20wt%.

[0027] Among them, the molecular weight of collagen is less than 1kDa.

[0028] Among them, the aloe extract is desalted aloe gel powder, and its components are: desalted aloe gel powder with a molecular weight greater than or equal to 1000kDa accounts for 40wt%, desalted aloe gel powder with a molecular weight of 200kDa-1000kDa acc...

Embodiment 3

[0032] A composition for promoting skin barrier repair, which comprises the following components in parts by weight: trehalose 15wt%, sodium hyaluronate 20wt%, centella asiatica extract 15wt%, spirulina polysaccharide 15wt%, collagen 12wt%, aloe vera Extract 20wt%, ceramide 1wt%, sodium polyglutamate 3wt%, ascorbyl glucoside 2wt%, acetylglucosamine 2wt%.

[0033] Wherein, the composition of sodium hyaluronate is: sodium hyaluronate with a molecular weight of 850k-1600kDa accounts for 70wt%, sodium hyaluronate with a molecular weight of 1800k-2500kDa accounts for 20wt%, and sodium hyaluronate with a molecular weight of 3k-10kDa accounts for 10wt%.

[0034] Among them, the molecular weight of collagen is less than 1kDa.

[0035] Among them, the aloe extract is desalted aloe gel powder, and its components are: desalted aloe gel powder with a molecular weight greater than or equal to 1000kDa accounts for 60wt%, desalted aloe gel powder with a molecular weight of 200kDa-1000kDa acc...

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Abstract

The invention belongs to the technical field of biomedical, and specifically relates to a composition for promoting skin barrier repair and an application thereof. The composition for promoting skin barrier repair includes the following components in parts by weight: 10-20 wt% of trehalose, 10-30 wt% of sodium hyaluronate, 5-15 wt% of a herba centellae extract, 5-15 wt% of spirulina polysaccharide, 5-15 wt% of collagen, 5-20 wt% of an aloe extract, 1-5 wt% of ceramide, 1-5 wt% of poly(sodium L-glutamate), 1-2 wt% of ascorbyl glucoside, and 0.5-2 wt% of acetylchitosamine. The prepared composition can be used for promoting the repair after skin barriers are damaged, is especially suitable for repair of skin barrier damage after laser cosmetic treatment.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a composition for promoting skin barrier repair and its application. Background technique [0002] The skin barrier is the natural guard of the human skin. Everyone has a natural skin barrier on the surface of the skin, which is composed of the human epidermal stratum corneum and sebum membrane. The stratum corneum is the outermost layer of the skin, mainly composed of keratin, and filled with lipids, mucopolysaccharides, natural moisturizing factors and other ingredients between the horny cells. The stratum corneum has the functions of skin protection, sun protection, moisturizing, absorption and aesthetics. [0003] The skin barrier is damaged, that is to say, the stratum corneum and sebum membrane of the skin are damaged, and the stratum corneum and sebum membrane are damaged. The common reasons are as follows: (1) excessive cleansing; (2) exfoliation; (3) mask Improper ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/42A61K8/60A61K8/65A61K8/67A61K8/73A61K8/88A61K8/9789A61K8/9794A61P17/00A61Q19/00
CPCA61K8/42A61K8/60A61K8/65A61K8/676A61K8/73A61K8/735A61K8/736A61K8/88A61K2800/592A61Q19/00A61K8/9789A61K8/9794A61P17/00
Inventor 余绍蕾黄英红李倩文杨智超唐昊
Owner GUANGZHOU GUOYU MEDICAL TECH
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