Chinese herbal compound for reducing weight and lowering lipid as well as preparation method and application of Chinese herbal compound

A production method and technology of traditional Chinese medicine, which are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of few oral weight loss drugs, large trauma of weight loss surgery, and many surgical contraindications, etc., and achieve improvement. Effects of multiple indicators, weight loss, and improvement of islet beta cell function

Inactive Publication Date: 2018-10-16
NINGBO NO 2 HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of obesity is mainly through lifestyle intervention, drug therapy and surgery. The more serious obesity requires the latter two treatment methods. Bariatric surgery has a greater trauma, greater surgical risk, and many surgical contraindications , narrow adaptability, generally not as the first choice, and there are very few oral weight-loss drugs available. The former phentermine and sibutramine were withdrawn from the market by the FDA (Food and Drug Administration) because of serious cardiovascular risks , so it is very important to find a drug that has a definite curative effect, is safe and reliable, and can be used for a long time

Method used

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  • Chinese herbal compound for reducing weight and lowering lipid as well as preparation method and application of Chinese herbal compound
  • Chinese herbal compound for reducing weight and lowering lipid as well as preparation method and application of Chinese herbal compound
  • Chinese herbal compound for reducing weight and lowering lipid as well as preparation method and application of Chinese herbal compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] A traditional Chinese medicine compound for weight loss and fat reduction, which is made of the following raw materials in parts by mass:

[0054] Black plum 5g, Yu Liren 5g, gardenia 5g, cassia seed 5g, turmeric 5g and lotus leaf 5g.

[0055] The preparation of the traditional Chinese medicine compound for weight loss and fat reduction comprises the following steps:

[0056] According to the above-mentioned mass parts, each raw material required for the Chinese medicine compound for weight loss and fat-lowering is weighed;

[0057] Cut 5 g of lotus leaves that have been weighed into pieces, and put them into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obtain extract one;

[0058] Beat 5 g of turmeric and 5 g of cassia seeds into coarse powder to form mixture 1;

[0059] Putting the above-mentioned mixture 1 into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obtain extract 2;

[0060] T...

Embodiment 2

[0065] A traditional Chinese medicine compound for weight loss and fat reduction, which is made of the following raw materials in parts by mass:

[0066] 30g of ebony plum, 30g of Yu Liren, 30g of gardenia, 30g of cassia seed, 30g of turmeric and 30g of lotus leaf.

[0067] The preparation of the traditional Chinese medicine compound for weight loss and fat reduction comprises the following steps:

[0068] According to the above-mentioned mass parts, each raw material required for the Chinese medicine compound for weight loss and fat-lowering is weighed;

[0069] Cut 30 g of lotus leaves that have been weighed into pieces, and put them into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obtain extract one;

[0070] Beat 30g of turmeric and 30g of cassia seeds into coarse powder to form mixture 1;

[0071] Putting the above-mentioned mixture 1 into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obta...

Embodiment 3

[0077] A traditional Chinese medicine compound for weight loss and fat reduction, which is made of the following raw materials in parts by mass:

[0078] 50g of ebony plum, 50g of Yu Liren, 50g of gardenia, 50g of cassia seed, 50g of turmeric and 50g of lotus leaf.

[0079] The preparation of the traditional Chinese medicine compound for weight loss and fat reduction comprises the following steps:

[0080] According to the above-mentioned mass parts, each raw material required for the Chinese medicine compound for weight loss and fat-lowering is weighed;

[0081] Cut 50 g of lotus leaves that have been weighed into pieces, and put them into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obtain extract one;

[0082] Beat 50g of turmeric and 50g of cassia seeds into coarse powder to form mixture 1;

[0083] Putting the above-mentioned mixture 1 into a pre-prepared supercritical carbon dioxide fluid extraction kettle for extraction to obtain...

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Abstract

The invention discloses a Chinese herbal compound for reducing weight and lowering lipid as well as a preparation method and application of the Chinese herbal compound. The Chinese herbal compound forreducing weight and lowering lipid is prepared from the following raw materials in parts by mass: 5-50 parts of fructus mume, 5-50 parts of Chinese dwarf cherry seed, 5-50 parts of fructus gardeniae,5-50 parts of semen cassiae, 5-50 parts of rhizoma curcumae longae and 5-50 parts of lotus leaf. The Chinese herbal compound for reducing weight and lowering lipid and the preparation method of the Chinese herbal compound have the beneficial effects that the Chinese herbal compound has good effects of reducing weight and lowering lipid, controlling weight, regulating glycolipid metabolism and improving insulin resistance, and is low in adverse response and low in price; in view of the deficiencies of traditional extraction and separation methods, a Chinese herbal compound combination with a specific ratio is optimized by means of the uniform design of system conditions aiming at the special properties of effective components of the raw material medicines of the Chinese herbal compound provided by the invention; furthermore, a supercritical carbon dioxide fluid extraction technology with proper conditions is explored to extract the effective components; the supercritical carbon dioxidefluid extraction technology is less in used organic solvents, high in extraction efficiency and separation efficiency, strong in operability and low in production cost, thus being suitable for large-scale production.

Description

technical field [0001] The invention relates to the technical field of compound traditional Chinese medicines, in particular to a traditional Chinese medicine compound for weight loss and fat reduction, a preparation method and application thereof. Background technique [0002] With the progress of society and the improvement of people's living standards, the rapid development of public health has brought about a further extension of the average life expectancy. The types of diseases among residents in our country have undergone major changes. Infectious diseases that once seriously affected the average life expectancy of residents have now retreated to the second line. , cardiovascular and cerebrovascular diseases, malignant tumors, diabetes, high blood pressure and other diseases have become the main factors that endanger human health, and studies have shown that these diseases are closely related to obesity. Abdominal obesity, also known as central obesity, is the cause of...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P3/04
CPCA61K36/482A61K36/62A61K36/736A61K36/744A61K36/9066A61K2236/37A61P3/04A61K2300/00
Inventor 贺晓立王军余静李红山沈力
Owner NINGBO NO 2 HOSPITAL
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