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Antibacterial care solution composition and application thereof

The technology of a composition and care solution, which is applied in the field of antibacterial and antibacterial agents, can solve the problems of weak microbial killing and inhibition, irritation, corneal damage, etc., and achieve a good effect of antibacterial and antibacterial effects

Inactive Publication Date: 2018-09-14
合肥昂诺新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But usually can contain a small amount of antiseptic and disinfectant in this contact lens care solution, these chemical substances have certain irritation to human body, long-term use can cause damage to people's cornea, in addition, although the bacteriostasis in contact lens The composition has a broad spectrum, but its killing and inhibiting power against certain specific microorganisms is weak, so it cannot effectively solve the problem of inflammation and infection caused by long-term wearing of contact lenses
[0004] In addition, since the chemical components in the contact lens care solution are easily oxidized in the air and deteriorate, most contact lens care solutions can only be used for a maximum of 24 hours, and need to be replaced after the expiration date, which is infrequent Users who need to wear it bring trouble

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A bacteriostatic care liquid composition, according to the parts by mass, the composition includes the following components: 1.4 parts of methylparaben, 0.1 part of sodium pyrrolidone hydroxyate, 0.2 part of cetylpyridinium chloride, and 1.4 parts of nano-zinc , 0.5 parts of cooling agent, 0.3 parts of cationic surfactant, 2 parts of chlorobutanol, 1.4 parts of polyethylene glycol, 1 part of buffer, 3 parts of osmotic regulator, 1.3 parts of yew extract, deionized water 80 servings.

[0024] In the present embodiment, the preparation method of the Chinese yew extract is:

[0025] Wash and dry the branches and leaves of Taxus chinensis, crush the dried branches and leaves to 90 mesh, mix the dry powder and potassium hydrogen phosphate-sodium hydrogen phosphate buffer solution according to the volume ratio of 1:10, and use 350W power under the condition of ice bath at 35°C Ultrasonic processor disperses for 25 minutes, centrifuges the ultrasonically dispersed material at...

Embodiment 2

[0032] A bacteriostatic care liquid composition, according to the number of parts by mass, the composition includes the following components: 1.7 parts of methylparaben, 0.6 parts of sodium pyrrolidone hydroxy acid, 0.5 parts of cetylpyridinium chloride, 2.2 parts of nano-zinc , 0.8 parts of cooling agent, 0.6 parts of cationic surfactant, 4 parts of chlorobutanol, 1.7 parts of polyethylene glycol, 1.5 parts of buffer, 7 parts of osmotic regulator, 1.6 parts of yew extract, deionized water 90 servings.

[0033] In the present embodiment, the preparation method of the Chinese yew extract is:

[0034] Wash and dry the branches and leaves of Taxus chinensis, crush the dried branches and leaves to 100 mesh, mix the dry powder and potassium hydrogen phosphate-sodium hydrogen phosphate buffer solution according to the volume ratio of 1:10, and use it in an ice bath at 35-40°C Disperse with a 350W power ultrasonic processor for 30 minutes, centrifuge the ultrasonically dispersed mat...

Embodiment 3

[0041] A bacteriostatic care liquid composition, according to parts by mass, the composition includes the following components: 1.5 parts of methylparaben, 0.3 parts of sodium pyrrolidone hydroxy acid, 0.4 parts of cetylpyridinium chloride, 1.8 parts of nano-zinc 0.7 parts of cooling agent, 0.5 parts of cationic surfactant, 3 parts of chlorobutanol, 1.6 parts of polyethylene glycol, 1.4 parts of buffering agent, 5 parts of osmotic regulator, 1.5 parts of yew extract, deionized 85 parts of water.

[0042] In the present embodiment, the preparation method of the Chinese yew extract is:

[0043] Wash and dry the branches and leaves of Taxus chinensis, crush the dried branches and leaves to 90 mesh, mix the dry powder and potassium hydrogen phosphate-sodium hydrogen phosphate buffer solution according to the volume ratio of 1:10, and use 350W power under the condition of ice bath at 38°C Ultrasonic processor disperses for 28 minutes, centrifuges the ultrasonically dispersed mater...

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Abstract

The invention relates to the technical field of antibacterial agents and specifically relates to an antibacterial care solution composition and application thereof. The composition is prepared from the following ingredients of methylparaben, pyrrolidone sodium hydroxide, hexadecylpyridinium chloride, nano zinc, a freshener, a positive-ion surface active agent, acetone chloroform, polyethylene glycol, a buffer agent, a permeability regulator, taxus chinensis extractive and deionized water, wherein the taxu chinensis extractive is polypeptide compound which is extracted from taxus chinensis braches and leaves and has an antibacterial effect; the positive-ion surface active agent is benzalkonium chloride or benzalkonium bromide; the permeability regulator is a saturated sodium chloride, saturated potassium chloride or saturated glucose solution. The antibacterial care solution contains varieties of ingredients with antibacterial and sterilizing effects, the properties of chemical substances are stable, the property of the composition is gentle, and the antibacterial care solution composition can be applied to antibacterial and sterilizing storage of ocular prosthesis or contact lensesand has no irritation to the human body.

Description

technical field [0001] The invention relates to the technical field of antibacterial and antibacterial agents, in particular to an antibacterial nursing solution composition and its application. Background technique [0002] Contact lenses, also called contact lenses, are lenses worn on the cornea of ​​the eye to correct vision or protect the eyes. According to the softness and hardness of the material, it includes three types: rigid, semi-rigid, and soft. Contact lenses have brought great improvements to patients with refractive errors such as myopia, hyperopia, and astigmatism not only in terms of appearance and convenience. Moreover, it has a wide field of vision and realistic vision. In addition, it has also played a special role in controlling the development of myopia and astigmatism in young people, and treating special eye diseases. Contact lenses are worn directly on the cornea of ​​the eyeball and have a good invisible effect, so they are widely used among young ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N65/06A01N59/16A01N43/40A01N43/36A01N37/46A01N37/40A01N31/02A01P1/00
CPCA01N31/02A01N37/40A01N37/46A01N43/36A01N43/40A01N59/16A01N65/00A01N65/06
Inventor 杜菊荣
Owner 合肥昂诺新材料有限公司
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