Povidone iodine solution and preparation method thereof

A technology of povidone-iodine and solution, which is applied in the direction of pharmaceutical formulas, medical preparations with non-active ingredients, active ingredients of artificially synthesized polymer materials, etc., which can solve the problem of taking away skin heat and moisture, affecting milk quality, and affecting medicated baths Effects and other issues, to achieve the effects of non-toxic side effects, prevention and treatment of cow mastitis, labor and drug costs

Active Publication Date: 2018-08-17
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the dairy cow medicated baths currently on the market have a high water content, which makes the medicated bath drip after infiltrating the cow’s teats, does not adhere to the cow’s teats, or is easily rubbed off by the cow’s bed, which greatly affects the effect of the post-medication bath and causes waste of medication.
[0003] It can be seen from the article "Development of Nipple Liquid Protective Film and Observation of Its Application Effect" published by Zhou Qingmin, Heilongjiang Veterinary Science Research Institute, etc., that although its pres...

Method used

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  • Povidone iodine solution and preparation method thereof
  • Povidone iodine solution and preparation method thereof
  • Povidone iodine solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0035] A kind of povidone-iodine solution, by every 100g solution, its raw material composition sees the following table 1.

[0036] The formula table of table 1 embodiment 1~3

[0037] Raw materials (unit g)

Example 1

Example 2

Example 3

Elemental iodine

0.1

0.5

1.0

Fatty alcohol polyoxyethylene ether

5

10

15

pvp

1

1

1

PVA

2

2

2

Polyurethane 35

5

5

5

sodium alginate

0.5

0.45

0.4

Propylene Glycol

1

1

1

citric acid

0.2

0.2

0.2

Sodium citrate

0.4

0.4

0.4

water

margin

margin

margin

[0038] Its preparation method is as follows:

[0039] 1. Put iodine and fatty alcohol polyoxyethylene ether into the preparation tank A, open the steam valve, and raise the temperature to 30°C-80°C, preferably 50°C.

[0040] 2. Stir until the iodine is completely dissolved and set aside.

[0041] 3. Put water into...

Embodiment 4

[0044] Example 4 is basically the same as Example 2, except that the surfactant used is different, specifically replacing 1g of fatty alcohol polyoxyethylene ether with 1g of lauryl dimethyl amine oxide

Embodiment 5

[0046] Example 5 is basically the same as Example 1, except that the plasticizer used is different, specifically, 1 g of phthalates is used instead of 1 g of propylene glycol.

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Abstract

The invention relates to a povidone iodine solution and a preparation method thereof. 100 g of povidone iodine solution is mainly prepared from, by weight, 0.1-3 g of elementary substance iodine, 1-5g of PVP, 1-10 g of polyvinyl alcohol, 2-10 g of polyurethane, 0.1-5 g of sodium alginate, 0.2-5 g of organic acid, 5-35 g of surfactant, 1-3 g of plasticizer and the balance water and pH adjuster. The povidone iodine solution is safe, reliable, high in stability and good in film-forming effect, formed film is high in toughness and does not easily fall off, the drug efficacy is durable, the antibacterial effect is ensured, a lot of labor and drug application cost can also be saved at the same time, and the povidone iodine solution is suitable for large-scale dairy cattle breeding farms.

Description

technical field [0001] The invention relates to the technical field of veterinary disinfectants, in particular to a povidone-iodine solution and a preparation method thereof. Background technique [0002] In the dairy farming industry, dairy cow mastitis has always been a problem for dairy farmers, and it is also one of the main causes of economic losses for dairy farmers. Every time before and after milking, the nipples of cows should be disinfected to prevent and control the occurrence of mastitis in cows, especially after dipping plays an important role in preventing mastitis in cows. Most of the dairy cow medicated baths currently available in the market have a high water content, which makes the medicated bath drip after infiltrating the cow's teats, does not adhere to the cow's teats, or is easily rubbed off by the cow's bed, which greatly affects the effect of the post-medication bath and causes waste of medication . [0003] It can be seen from the article "Develop...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/32A61K47/34A61K47/10A61K31/79A61P31/02A61P15/14
CPCA61K9/0041A61K9/7015A61K31/79A61K47/10A61K47/32A61K47/34A61P15/14A61P31/02
Inventor 徐奇清李成应周淑贞付良凯黄海青
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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