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Pharmaceutical composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and preparation method thereof

A composition and drug technology, which can be used in the field of compositions for adjuvant conditioning of tumor radiotherapy and chemotherapy patients, and can solve the problems of insignificant efficacy and the like

Active Publication Date: 2018-06-08
QINGHAI SPRING MEDICINAL RESOURCES TECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, most of the health care products for radiation damage currently on the market have no obvious effect, and there are few medicines or health care products with definite effects for the auxiliary conditioning of tumor radiotherapy and chemotherapy patients. Therefore, it is of great significance to develop alternative products with better effects

Method used

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  • Pharmaceutical composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and preparation method thereof
  • Pharmaceutical composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and preparation method thereof
  • Pharmaceutical composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The preparation technology of embodiment 1 granule of the present invention

[0070] 1. Study on the extraction and inclusion process of cinnamon

[0071] 1.1 Study on extraction process of cinnamon volatile oil

[0072] Crush the cinnamon to about 10 meshes for later use. Weigh 300 g of cinnamon coarse powder as a portion, take 3 portions in total, and investigate whether the medicinal material is soaked and the oil extraction time (steam distillation extraction). The oil output was recorded at different times until the oil output basically stopped increasing. The results are shown in Table 1.

[0073] Table 1 volatile oil extraction investigation

[0074]

[0075] From the above results, it can be seen that soaking has little effect on the extraction effect of volatile oil. The volatile oil has been basically extracted after 4 hours of extraction from medicinal materials, and there is only a small increase in 6 hours. After 8 hours, the amount of oil has no long...

Embodiment 2

[0196] The stability experiment of embodiment 2 granules of the present invention

[0197] The granules of the pharmaceutical composition of the present invention are tested for the content of crude polysaccharides, adenosine, and astragaloside IV at different times under airtight, dark, and normal temperature conditions. The detection items, basis, and results are as follows:

[0198] Inspection items and basis: crude polysaccharide - Q / QHCT004-2015 (enterprise standard)

[0199] Adenosine—health food inspection and technical evaluation specification (2003)

[0200] Astragaloside IV——Q / QHCT004-2015 (enterprise standard)

[0201] Sample placement conditions: constant temperature 38°C, relative humidity 75%.

[0202] Month Zero Results

[0203]

[0204] first month result

[0205]

[0206] second month result

[0207]

[0208] 3rd month results

[0209]

Embodiment 3

[0210] Example 3 Verification of the daily dosage of the pharmaceutical composition of the present invention

[0211] The daily dosage of the pharmaceutical composition of the present invention and the reference daily dosage of the Pharmacopoeia are shown in Table 22:

[0212] Table 22 Daily dosage of the present invention and Pharmacopoeia reference daily dosage

[0213] raw material

Daily dosage of the present invention

Reference daily dosage of medicinal materials

Cordyceps sinensis

0.5g

3～9g

Broken Ganoderma Lucidum Spore Powder

1.5g

6～12g

angelica

1g

6～12g

Astragalus

5g

9～30g

Cinnamon

1g

1～5g

licorice

3g

2～10g

[0214] It can be seen from the above that the pharmaceutical composition of the present invention adopting the above formula, Cordyceps sinensis, Ganoderma lucidum spore powder, Angelica sinensis and Radix Astragali are significantly lower than the pharmacopoeia ref...

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Abstract

The invention belongs to the field of medicines or health products, and particularly relates to a composition for assisting conditioning of tumor radiotherapy and chemotherapy patients and a preparation method thereof. The technical problem solved by the invention is to provide a brand-new composition for replenishing uprightness of a body and enhancing physique, especially for the assisting conditioning of the tumor chemotherapy and the radiotherapy patients, and a role of auxiliary protection against radiation hazards. The composition of the invention adopts cordyceps, reishi shell-broken spore powder, radix angelicae sinensis, radix astragali, cortex cinnamomi and radix glycyrrhizae as raw material medicines, and the weight ratios are as follows: 1 to 8 parts of cordyceps, 5 to 30 partsof reishi shell-broken spore powder, 3 to 25 parts of radix angelicae sinensis, 10 to 80 parts of radix astragali, 3 to 25 parts of cortex cinnamomi and 10 to 60 parts of radix glycyrrhizae. Comparedwith similar products on the market, the composition for the assisting conditioning of the tumor radiotherapy and the chemotherapy patients has the advantages of a clear effect, a stable curative effect and being controllable, and provides public with a brand-new choice.

Description

technical field [0001] The invention belongs to the field of medicine or health care products, and in particular relates to a composition for auxiliary conditioning of tumor radiotherapy and chemotherapy patients and a preparation method thereof. Background technique [0002] Tumor chemotherapy is a treatment method that uses chemical drugs to prevent the proliferation, invasion, and metastasis of cancer cells until it finally kills cancer cells. Because of its low selectivity, it will inevitably damage the normal body while killing cancer cells. In the west, bone marrow suppression (leukopenia, thrombocytopenia, red blood cell decrease), gastrointestinal reactions (nausea, vomiting, diarrhea, constipation), organ toxicity (drug-induced liver injury, renal insufficiency, pulmonary fibrosis, neurotoxicity) reaction, heart failure) and other adverse reactions. [0003] Tumor radiotherapy is a local treatment method that uses radiation to treat tumors. Radiation therapy can c...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61P35/00
CPCA61K36/068A61K36/074A61K36/232A61K36/481A61K36/484A61K36/54A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 张雪峰杨婷
Owner QINGHAI SPRING MEDICINAL RESOURCES TECHNOLOGY CO LTD
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