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Medicine for treating inflammation and carbuncle of breasts of dairy cattle and preparation method thereof

A kind of medicine and breast technology, which is applied in the field of medicine and its preparation for the treatment of dairy cow udder inflammation and carbuncle, can solve the problems of acute clinical mastitis, antibiotic residues, waste, etc., and achieve the promotion of healthy and sustainable development. The effect of high content and stable properties

Active Publication Date: 2018-03-27
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In summary, dairy cow udder inflammation and carbuncle occur in a wide range of farms. If not treated in time and effectively prevented, it is easy to develop into acute clinical mastitis, which will increase the difficulty of treatment and increase the cost of treatment. Declining milk quality, abandonment, and more serious dairy farm losses
The consequences of the clinical use of antibiotics to treat the disease are mainly the continuous increase of drug-resistant strains that seriously affect the treatment effect and the problem of antibiotic residues

Method used

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  • Medicine for treating inflammation and carbuncle of breasts of dairy cattle and preparation method thereof
  • Medicine for treating inflammation and carbuncle of breasts of dairy cattle and preparation method thereof
  • Medicine for treating inflammation and carbuncle of breasts of dairy cattle and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A medicine for treating cow udder inflammation and carbuncle, comprising the following components in parts by weight: 5 g of total alkaloid extract of Changshan Mountain, 10 g of castor oil, 10 g of peppermint oil, 10 g of white petrolatum, 10 g of yellow wax, 1 g of borneol, and 1 g of bromogeramine.

[0038]Wherein, the preparation method of Changshan total alkaloid extract: take Changshan dry root 1000g, pulverize, pass through 120 mesh, add 50% ethanol aqueous solution by volume percentage, reflux extraction 2 times (add 3 times of amount for the first time and reflux for 3.0h, second Add 5 times the amount at a time, reflux for 2.0h), filter, and concentrate the extract under reduced pressure to recover ethanol (concentrate under reduced pressure under the conditions of 0.09MPa and 50°C). Add 2% hydrochloric acid to the extract to adjust the pH to 2-3, wash with ether three times to remove impurities, and obtain an acidic filtrate (concentrate). Then add solid sodi...

Embodiment 2

[0041] A medicine for treating cow udder inflammation and carbuncle, comprising the following components in parts by weight: 20g of total alkaloid extract of Changshan Mountain, 30g of castor oil, 30g of peppermint oil, 30g of white petrolatum, 20g of yellow wax, 10g of borneol, and 5g of bromogeramine.

[0042] Wherein, the preparation method of Changshan total alkaloid extract: take Changshan dry root 1000g, pulverize, pass through 120 mesh, add 90% ethanol aqueous solution by volume percentage, reflux extraction 2 times (add 9 times of amount for the first time and reflux for 1.0h, second Add 8 times the amount at a time, reflux for 1.0h), filter, extract the solution and concentrate under reduced pressure, and recover ethanol (concentrate under reduced pressure under the conditions of 0.09MPa and 60°C). Add 2% hydrochloric acid to the extract to adjust the pH to 2-3, wash with ether three times to remove impurities, and obtain an acidic filtrate (concentrate). Then add sol...

Embodiment 3

[0045] A medicine for treating cow udder inflammation and carbuncle, comprising the following components in parts by weight: 10g of total alkaloid extract of Changshan Mountain, 15g of castor oil, 20g of peppermint oil, 20g of white petrolatum, 10g of yellow wax, 8g of borneol, and 4g of bromogeramine.

[0046] Wherein, the preparation method of Changshan total alkaloid extract: take Changshan dry root 1000g, pulverize, pass through 120 mesh, add 70% ethanol aqueous solution by volume percentage, reflux extraction 2 times (for the first time add 7 times of amount and reflux for 2.0h, second Add 6 times the amount at a time, reflux for 1.5h), filter, and concentrate the extract under reduced pressure to recover ethanol (concentrate under reduced pressure under the conditions of 0.09MPa and 50°C). Add 2% hydrochloric acid to the extract to adjust the pH to 2-3, wash with ether three times to remove impurities, and obtain an acidic filtrate (concentrate). Then add solid sodium ca...

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Abstract

The invention discloses a medicine for treating inflammation and carbuncle of breasts of dairy cattle and a preparation method thereof. The medicine for treating inflammation and carbuncle of breastsof dairy cattle is prepared from the following components in parts by weight: 5-20 parts of antifebrile dichroa total alkaloids extract, liquid auxiliary material: 10-30 parts of caster oil, 10-30 parts of oleum menthae, solid auxiliary materials: 10-30 parts of white Vaseline, 10-20 parts of beeswax and 1-10 parts of borneol and a preservative: 1-5 parts of bromogeramine. The medicine for treating inflammation and carbuncle of breasts of dairy cattle disclosed by the invention has the functions of inhibiting bacteria and eliminating inflammation and eliminating swelling and drawing out poison, is good in stability, green and safe and good in curative effect, and can avoid antibiotics residues effectively.

Description

technical field [0001] The invention relates to the technical field of veterinary medicine, in particular to a medicine for treating cow udder inflammation and carbuncle and a preparation method thereof. Background technique [0002] Cow mastitis is an inflammatory reaction produced by the mammary glands of dairy cows under physical, chemical and microbial stimulation, and is one of the most important diseases affecting the development of the dairy industry in the world. The diseased cows eliminated due to intractable dairy cow mastitis and necrotic milk areas in my country account for about 50% of the total number of diseased cows eliminated. Secondly, cow udder carbuncle occurs in both clinical mastitis and subclinical mastitis, and bacterial invasion and milk stasis are the two main pathogenic factors. Common pathogenic bacteria such as Streptococcus agalactiae, Staphylococcus aureus, and Streptococcus dysgalactiae are the main causes of disease, and these pathogens usua...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/06A61K47/06A61K47/44A61K47/10A61K47/18A61P15/14A61P29/00A61P31/04A61P31/02A61K36/534A61K31/045
CPCA61K9/0041A61K9/06A61K31/045A61K36/185A61K36/47A61K36/534A61K47/06A61K47/10A61K47/186A61K47/44A61K2300/00
Inventor 王玲郭志廷柏建明杨峰郭文柱刘宇魏小娟周绪正牛建荣杨珍张彬罗金印
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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