Novel dosage form of diabetic nephropathy for treating decoction-free astragalus membranaceus granules and application thereof

Abstract

The invention discloses a new dosage form of Huangqi decoction free decoction granules for treating diabetic nephropathy and its application. 10‑30 parts of Ophiopogon japonicus, 5‑15 parts of Schisandra chinensis, 5‑15 parts of Zhi Licorice and 25‑35 parts of Rehmannia glutinosa; made according to the following method: Step 1: Take medicinal materials, chop them, add water to soak, and decoct Multiple times, collect each decoction and combine; Step 2: After decoction is centrifuged or sedimentation filtered, concentrate, place in refrigeration, add ethanol, mix well, and place overnight; Step 3: Take out the next day and filter, precipitate The substance is washed with ethanol, the washing liquid is combined with the filtrate, and after the ethanol is recovered under reduced pressure, it is concentrated and then placed in a cold place to stand still, filtered, and the filtrate is evaporated at low temperature to a thick paste to obtain an extract; step 4: finally combine the extract with The auxiliary materials are kneaded, granulated, and dried to obtain Huangqi Decoction Free Fried Granules. The invention overcomes the disadvantages of Huang's decoction preparation, decoction, inconvenient carrying, easy deterioration, bitter soup and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a new dosage form of Huangqi Decoction Mianjian Granules for treating diabetic nephropathy and its application. Background technique [0002] The onset of diabetes is hidden, and patients have no obvious symptoms in the early stage of onset. A considerable number of patients seek medical treatment due to diabetes-related complications, and chronic complications of diabetes are the most important factor that threatens the health of patients. As the course of diabetes progresses, serious complications arise, such as diabetic macroangiopathy, microangiopathy, infection, and neuropathy. Among these chronic complications, especially diabetic vascular disease is the most harmful. Diabetic nephropathy (diabetic nephropathy, DN) is the most important microvascular complication of diabetes. Epidemiological studies have shown that the incidence of diabetic nephropa...

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Problems solved by technology

[0003] The object of the present invention is to provide a new dosage form of Huangqi decoction decoction-free granules for treating diabetic nephropathy and its application, so as to overcome the inconvenience of Huangshi decoction formulation, decoction, carrying, easy deterioration, bitter taste of soup and large quantity and other shortcomings

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