Drug for treating diabetes and preparation method thereof

A diabetes drug and diabetes technology, applied in the field of diabetes treatment, can solve the problems of inability to completely improve the normal secretion of insulin, poor human body, and high disability rate, and achieve the effects of improving the cure rate, enhancing immunity, and protecting ingredients.

Inactive Publication Date: 2018-01-09
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the change of market economy, the change of people's life style and diet, more and more diabetic patients, and they tend to be younger. Diabetes is one of the world's three major chronic diseases that threaten human health and life, and its mortality rate is second only to The incidence rate of cardiovascular and cerebrovascular diseases and cancer ranks first among the three chronic diseases; the direct harm of diabetes to the human body can cause secondary complications; there are many drugs for treating diabetes at home and abroad, including artificial injection of insulin, but most of them can only maintain the blood pool, The urine sugar value tends to be normal, and the normal secretion of insulin cannot be completely improved. There is no medicine to cure it. Most of the injected insulin contains hormones, which have adverse effects on the human body: Western medicine is used for drug treatment, but because western medicine contains a lot of toxicity to the human body. Chemical ingredients with strong side effects, so taking western medicine for a long time will seriously damage the liver and kidney of the human body. If it is not treated in time and correctly, it will inevitably cause complications and a high disability rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Extract the medicine preparation method for treating diabetes from Periplaneta americana, adopt following technology to realize:

[0031] A, the dried Periplaneta americana body is crushed through a 10-mesh sieve, and the obtained Periplaneta americana coarse powder is soaked in 60% ethanol, so that the ethanol liquid level is higher than the coarse powder liquid level 5cm, airtightly preserved for 18 months, Prepare coarse powder mixed liquor;

[0032] B. Ultrasonic extraction of the coarse powder mixture obtained in step A for 3 times at a temperature of 30°C. The ultrasonic power is: 20KHz. When extracting the coarse powder mixture for the first time, increase the weight of the coarse powder to 5 times the concentration of 60%. The ethanol, the extraction time is 30min; After the second time, the ethanol of 3 times the concentration of 60% of the thick powder weight is extracted each time, and the extraction time is 2min; the combined extracts are filtered to obtain ...

Embodiment 2

[0044] Extract the medicine preparation method for treating diabetes from Periplaneta americana, adopt following technology to realize:

[0045] A, the dried Periplaneta americana body is crushed through a 40-mesh sieve, and the obtained Periplaneta americana coarse powder is soaked in 95% ethanol, so that the ethanol liquid level is higher than the coarse powder liquid level 10cm, sealed for 7 days, and prepared Obtain coarse powder mixture;

[0046] B. Ultrasonic extraction of the coarse powder mixture obtained in step A at a temperature of 50°C for 5 times, the ultrasonic power is: 30KHz, when the coarse powder mixture is extracted for the first time, increase the weight of the coarse powder to 8 times the concentration of 95% The ethanol, extraction time is 60min; Extract the ethanol of thick powder weight 6 times of concentration 95% ethanol at every turn after the second time, extraction time is 50min; Merge extract, filter to obtain Periplaneta americana ethanol extract...

Embodiment 3

[0058] Extract the medicine preparation method for treating diabetes from Periplaneta americana, adopt following technology to realize:

[0059] A, the dried Periplaneta americana body is crushed through a 20-mesh sieve, and the obtained Periplaneta americana coarse powder is soaked in 75% ethanol, so that the ethanol liquid level is higher than the coarse powder liquid level 8cm, and it is sealed for 12 months. Prepare coarse powder mixed liquor;

[0060] B, carry out ultrasonic extraction 3 times to the coarse powder mixture obtained in step A:

[0061] The first ultrasonic extraction: temperature 30°C, ultrasonic power 20KHz, add 5 times the weight of coarse powder with 75% ethanol, and the extraction time is 30 minutes;

[0062] The second ultrasonic extraction: the temperature is 35°C, the ultrasonic power is 23KHz, and the concentration of 75% ethanol is 3 times the weight of coarse powder, and the extraction time is 20 minutes;

[0063] The third ultrasonic extraction...

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PUM

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Abstract

The invention relates to a preparation method for a drug for treating diabetes. The method comprises the following steps: A) grinding American cockroach and soaking with ethyl alcohol, thereby acquiring a mixed solution; B) ultrasonically extracting the mixed solution at 30-50 DEG C under the ultrasonic powder of 20-30KHz, thereby acquiring an ethyl alcohol extraction; C) concentrating the ethyl alcohol extraction, thereby acquiring an American cockroach polypide ethyl alcohol concentrated solution; D) adding 7-10 times of water into the ethyl alcohol concentrated solution, stirring, rising temperature and standing by for layering; E) filtering the bottom water liquid acquired in the step D) and absorbing with activated carbon; F) filling the liquor containing the activated carbon acquiredin the step E) into a chromatographic column, discharging the liquor, washing with the activated carbon, removing the water washing agent, eluting with eluent and filtering, thereby acquiring the eluted filtrate; G) concentrating the eluted filtrate acquired in the step F), thereby acquiring an American cockroach extract for treating diabetes; H) drying and crushing the American cockroach extractfor treating diabetes acquired in the step G), thereby acquiring the end product of the American cockroach extract for treating diabetes. The end product has an obvious adjuvant therapeutic effect for treating diabetes.

Description

technical field [0001] The invention relates to the treatment of diabetes, in particular to a medicine for treating diabetes and a preparation method thereof. Background technique [0002] Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired biological action, or both. The long-term high blood sugar in diabetes leads to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. [0003] With the change of market economy, the change of people's life style and diet, more and more diabetic patients, and they tend to be younger. Diabetes is one of the world's three major chronic diseases that threaten human health and life, and its mortality rate is second only to The incidence rate of cardiovascular and cerebrovascular diseases and cancer ranks first among the three chronic diseases; the direct harm of diabetes to the human body can c...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P3/10A61P17/02A61P37/04
Inventor 郝振平徐溧
Owner KUNMING SINOWAY NATURAL PHARMA
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