Preparation method of source core of germanium-68 radioactive source

Abstract

The invention discloses a preparation method for a germanium-68 radioactive source core, and the method comprises the following steps: placing processed zirconium silicate particles in a reaction container; adding hydrochloric acid aqueous solution, germanium saline solution and germanium-68 saline solution, carrying out the uniform mixing and vibration reaction; discarding the supernatant, and carrying out the cleaning through deionized water; carrying out cleaning through absolute ethyl alcohol; carrying out the drying operation under the room temperature, and obtaining the germanium-68 radioactive source core. The prepared germanium-68 radioactive source core is uniform in radioactivity distribution, and the utilization rate of germanium-68 is high and the generated radioactive liquid waste is less. The method provided by the invention is short in reaction time, and the operation process is simple and easy to control. The method is high in production efficiency, and employs the low-concentration hydrochloric acid. The method enables the operation of a worker to be safe, and is small in radiation dosage. The chemical reagents employed in the method are conventional reagents sold in the market, are non-poisonous, are convenient to purchase, are cheap in price, and are low in production cost. Zirconium silicate is high in radiation resistance performances, is uniform in particles, is good in adsorption effect, is easy to store, and is good in filling uniformity.

Description

technical field [0001] The invention belongs to the field of nuclear technology, and in particular relates to a preparation method of germanium-68 radioactive core. Background technique [0002] Positron emission tomography (PET), also known as molecular imaging or biochemical imaging, is a new technology developed in nuclear medicine. Horizontal nuclear medicine diagnostic sign. PET has been widely used in the clinical diagnosis of various diseases and the research of basic medicine. Due to detector inconsistency, isotope decay, human tissue absorption of isotope, random error and scattering error seriously affect the image quality and diagnostic effect of PET, and image distortion often occurs. Attenuation correction is one of the important factors affecting the quality of PET images. Every time PET imaging is used, it must be corrected to ensure the imaging quality and diagnostic effect. [0003] The most common sources used for PET attenuation correction are germanium...

AI Technical Summary

Problems solved by technology

The disadvantage is that the ion exchange resin has poor radiation resistance, and the resin will be aged or broken during long-term use, which will cause the line uniformity of the radioactive source to increase, and the calibration effect will not be achieved, so that the PET image will be visualized. distortion of

Chinese patent ZL 2009 1 0069323.5 discloses a method of preparing germanium under high-concentration sulfuric acid solution using radiation-resistant silica as an adsorbent[ 68 The method of Ge] radioactive source source core overcomes the shortcoming of above-mentioned technology, but still has deficiency, is that high-concentration sulfuric acid has potential safety hazard to operator during operation, produces heat in reaction process and makes reaction temperature rise, causes a small amount of germanium- 68 is volatilized, centrifugation is required after the reaction, and the volume of cleaning solution required to clean the source core to neutrality is large, resulting in a large amount of waste liquid and increasing the cost of waste treatment

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