Formula and preparation method of external preparation for allergic rhinitis

Abstract

The invention discloses a formula and a preparation method of an external preparation for allergic rhinitis, wherein the components of the external preparation mainly comprise cordyceps sinensis essential oil, cornu cervi pantotrichum essential oil, ginseng essential oil, peppermint essential oil, menthol, fructus xanthii oil, flos magnoliae liliflorae oil and menthol, and the cordyceps sinensis essential oil, the cornu cervi pantotrichum essential oil, the ginseng essential oil, the peppermint essential oil, the fructus xanthii oil and the flos magnoliae liliflorae oil are prepared from cordyceps sinensis, cornu cervi pantotrichum, ginseng, peppermint, fructus xanthii and flos magnoliae liliflorae through a supercritical CO2 extraction and steam distillation combined method. The preparation process of the preparation mainly comprises carrying out supercritical extraction on the Chinese herbs to obtain various oil-like products, extracting mixed volatile oil through a distillation method, uniformly mixing with peppermint, and sub-packaging. According to the present invention, the preparation product can effectively treat allergic rhinitis, can provide a certain treatment effect for acute and chronic rhinitis, dry rhinitis, nasal congestion, nose running, sneezing, headache, hyposmia, nasal obstruction, common cold, belly pain, diarrhea, vomiting, mosquito biting, dyspepsia, scorch by soup and fire, toothache, headache, carsickness, sea sickness and the like, and further has effects of summer-heat removing, refreshing, wind expelling, disinfection, inflammation eliminating, and the like.

Description

technical field [0001] The invention relates to a formula and a preparation method of an external preparation for allergic rhinitis, belonging to the field of traditional Chinese medicine extraction. Background technique [0002] Allergic rhinitis (AR) is an abnormal reaction in the nose caused by the body's increased sensitivity to certain allergens. The main symptoms are sudden and recurrent nasal itching, sneezing, runny nose and nasal congestion. In the past 20 years, with the improvement of industrialization level and the pollution of human environment, the patients with allergic rhinitis have increased year by year, and the incidence rate of AR in central cities of my country is 8.7%-24.1%. At present, a large number of clinical observations have shown that there are some problems in western medicine treatment: ① antihistamines can not completely relieve symptoms for some patients, especially AR patients with vasomotor rhinitis, and it is difficult to avoid side effec...

AI Technical Summary

Problems solved by technology

At present, a large number of clinical observations have shown that there are some problems in western medicine treatment: ① antihistamines can not completely relieve symptoms for some patients, especially AR patients with vasomotor rhinitis, and it is difficult to avoid side effects such as saliva; ② topical hormone- Although the curative effect is good, but - long-term use, the side effects on the body mechanism are still relatively large

For expensive traditional Chinese medicinal materials, the extraction rate is low and the cost is high by ordinary extraction technology, and the components and contents extracted by different extraction methods are not exactly the same. The combined use of extraction methods can improve the extraction rate of active components of traditional Chinese medicine, but there are few related studies

[0004] Every step of the production process of the product affects the final quality of the finished product. The research on the pre-treatment process, such as cleaning and drying, is often ignored. Only by selecting the appropriate technology can the quality of Chinese medicinal materials be guaranteed and the loss of active ingredients can be reduced. In order to simplify the production process and reduce production costs For the extraction of various medicinal materials, the mixed extraction method is often used. Since the extraction of active ingredients of medicinal materials is affected by factors such as extraction conditions such as solvent, temperature, and extraction time, it is difficult to screen out the most suitable for the extraction of various medicinal materials by using mixed extraction of various medicinal materials. Under the optimal conditions, simultaneous extraction of multiple medicinal materials not only results in low extraction efficiency, but also has complex components and low content of active ingredients, resulting in insignificant curative effect of the prepared preparation

[0005] Due to the shaft, impeller and other rotating parts of the traditional mechanical impeller mixing equipment, it is easy to wear and fatigue, has many faults, and the production efficiency is low, and the mechanical mixing needs a dynamic seal. If the oil leaks at the seal, it will pollute the medium or the mixed material in the container. Affect product quality and safety, the vortex formed during mechanical mixing seriously affects the uniformity of mixing