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Hemostatic drug composition and application thereof

A composition and drug technology, applied in the field of medicinal chemistry, can solve the problems of high price, susceptibility to infection, slow degradation, etc., and achieve the effects of stable particle size distribution, promotion of healing, and good biocompatibility

Inactive Publication Date: 2017-07-14
SHENYANG JIANZHU UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these products have more or less problems, such as the use of animal-derived raw materials, slow degradation, susceptibility to infection, high price, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A hemostatic medicinal composition, comprising: 35 parts of nano silicon dioxide, 40 parts of montmorillonite and 10 parts of honeysuckle in parts by weight. Wherein the particle size of the nano silicon dioxide is 50-80 nm, and the particle size of the montmorillonite and the honeysuckle is 200-400 μm. Weigh the nano-silica, montmorillonite and honeysuckle according to the proportion and mix them evenly to obtain the hemostatic powder.

Embodiment 2

[0024] A hemostatic medicinal composition, comprising, in parts by weight: 30 parts of nanometer silicon dioxide, 40 parts of montmorillonite, 20 parts of honeysuckle, and 2 parts of ethyl cellulose. The particle size of the nano silicon dioxide is 50-80nm, and the particle size of the montmorillonite and the honeysuckle is 200-400 μm. Weighing nano silicon dioxide, montmorillonite and honeysuckle according to the proportion and mixing them uniformly to obtain a finished product. The finished product is mixed with ethyl cellulose to make hemostatic granules.

Embodiment 3

[0026] A hemostatic medicinal composition, comprising: 35 parts of nano silicon dioxide, 35 parts of montmorillonite and 15 parts of honeysuckle in parts by weight. The particle size of the nano silicon dioxide is 50-80nm, and the particle size of the montmorillonite and the honeysuckle is 200-400 μm. Weighing nano silicon dioxide, montmorillonite and honeysuckle according to the proportion and mixing them uniformly to obtain a finished product. Put the finished product into a hydrophilic non-woven bag to make a first aid kit.

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PUM

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Abstract

The invention provides a hemostatic drug composition and application thereof. The hemostatic drug composition is prepared from the following components in parts by weight: 30 to 40 parts of nanometer silicon dioxide, 30 to 40 parts of montmorillonite, and 10 to 20 parts of honeysuckle flower. The hemostatic drug composition has the advantages that the nanometer silicon dioxide and the montmorillonite have the blood condensing function, the honeysuckle flower powder has the sterilizing and inflammation diminishing functions, various types of wound blooding can be quickly stopped, the effects of diminishing inflammation and relieving pain are realized, and the effect of promoting the wound healing is obvious.

Description

technical field [0001] The invention belongs to the field of medicinal chemistry, and in particular relates to a hemostatic pharmaceutical composition and application thereof. Background technique [0002] General surgery or trauma will cause blood wounds, and blood is an important substance in the human body. If the bleeding cannot be effectively stopped in time, it will cause the body to weaken, and massive bleeding will lead to hemorrhagic shock or even death. An important factor in the successful treatment of patients. The ideal local hemostatic material should have the requirements of rapid hemostasis, mild toxicity and tissue reaction, good biocompatibility, rapid degradation, convenient use, low price, accelerated tissue healing, and adaptability to different parts and types of hemorrhage and hemostasis. At present, there are various types of hemostatic drug products on the market, and the materials are various, and the common ones are chitosan, gelatin, collagen, an...

Claims

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Application Information

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IPC IPC(8): A61K36/355A61P7/04A61L24/00A61L24/02A61K33/06A61K33/00
CPCA61K33/00A61K33/06A61K36/355A61L24/0005A61L24/0015A61L24/0036A61L24/02A61L2300/10A61L2300/30A61L2300/418A61L2400/04A61K2300/00
Inventor 万晔刘晶张海啸彭磊
Owner SHENYANG JIANZHU UNIVERSITY
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