A kind of freeze-dried powder and preparation method thereof

Abstract

The invention relates to a freeze-dried powder and a preparation method thereof, belonging to the field of cosmetics. The lyophilized powder provided by the present invention comprises the following components in terms of weight percentage: tripeptide-1 copper 0.1-2%, moisturizing agent 0.2-7%, excipient 0.1-23% and Deionized water balance. The present invention adopts betaine with lower consistency as a protective agent against solute migration, and the lyophilized powder prepared with the weight ratio of betaine and tripeptide-1 copper as 3:1 has no migration of colored substances and is stable good resolvability, normal appearance, and good resolubility; the freeze-dried powder obtained after the freeze-drying treatment of the present invention has a smooth and delicate appearance, good reproducibility, and good permeability; the cost of preparing the freeze-dried powder of the present invention is low, the raw material price is cheap, and the process is simple , does not require complex equipment, has low requirements on the professional quality of operators, is easy to implement, and can be used for large-scale industrial promotion and production.

Description

technical field [0001] The invention relates to a freeze-dried powder and a preparation method thereof, belonging to the field of cosmetics. Background technique [0002] Freeze-dried powder is a sterile powder made by ultra-low temperature freezing process under vacuum conditions, and it is a beauty product with repairing effect. The preparation of freeze-dried powder includes the screening of formula and the design of freeze-drying process; a formula of freeze-dried powder with good effect can often get twice the result with half the effort, and can effectively reduce various abnormal phenomena during the freeze-drying process, and the finished product after freeze-drying The appearance, resolubility, moisture content, shelf life and glass transition temperature of the product are all in line with industry standards. The formula of the lyophilized powder includes excipients and active substances. According to the properties of the active substances, choosing a suitable ex...

AI Technical Summary

Problems solved by technology

From the formula level, increasing the consistency can certainly weaken the migration of pigments, but the increase in consistency also increases the difficulty of sterile filtration. Generally, the pore size of sterile filtration is small, and increasing the consistency greatly reduces the rate of sterile filtration. Even if it cannot be filtered, it is necessary to add preservatives or high-temperature sterilization to reduce the risk of bacterial contamination. Moreover, increasing the consistency greatly affects the resolubility of the freeze-dried powder. Generally, an increase in the consistency will reduce the resolubility of the product.

Although the rapid freezing process can obtain a relatively perfect uniform and delicate freeze-dried powder, but this method is difficult to operate, the cost of equipment is high, the requirements for personnel are relatively high, and the cost consumption of various aspects is high.

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