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Developing type degradable urethra repairing stent

A technology of urethra and contrast agent, which is applied in the field of developing-type degradable repair urethral stents, which can solve the problems of inability to understand the shape and position of implanted materials, the vulnerability of patient tissues, and low electron density, etc., and achieve controllable and reduced degradation time. Effects of scar formation and promotion of healing and repair

Pending Publication Date: 2016-10-12
青岛蓝博云健康产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of these materials only contain elements with low electron density and low specific gravity, such as C, H, and O, and cannot be detected by X-rays, which makes it impossible for medical personnel to understand the specific shape and position of implanted materials in the body, and cannot place them accurately. At the lesion site, the patient's tissue is also vulnerable to injury, which brings difficulties to the operation. Therefore, the development-type degradable urethral repair stent is a research hotspot at present. The contrast agents mainly include barium and iodine. Barium is mainly used for esophagus and gastrointestinal contrast, while iodine is mainly used for contrast of bile duct and gallbladder, renal pelvis and urinary tract, arteries and veins

Method used

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  • Developing type degradable urethra repairing stent

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Effect test

Embodiment 1

[0058] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0059] Cooling: cooling by air cooling.

[0060] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0061] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add...

Embodiment 2

[0070] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0071] Cooling: cooling by air cooling.

[0072] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0073] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add...

Embodiment 3

[0082] Extrusion threaded pipe: Extrusion complete set of equipment includes extruder, traction device, sizing device, cooling device and supporting equipment. Extrusion temperature: 150°C. The extrusion material is a biodegradable material: polylactic acid-polyglycolic acid copolymer (PLGA). The pitch of the thread groove is: 10mm.

[0083] Cooling: cooling by air cooling.

[0084] Guachuang coating: through automatic dispensing machine and other equipment, glue is applied to the spiral groove of the outer wall of the threaded pipe, dried, washed with absolute ethanol, dried, and the healing and repairing functional material is a colloid solution made of polysaccharide .

[0085] The preparation method of the healing and repairing functional material is as follows: weigh 50g of chitosan powder, put it into a glass reaction vessel, add 130mL of propionic anhydride solution of acylating reagent, add 120ml of ethanol, stir evenly, control the reaction temperature at 35°C, add...

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Abstract

The invention relates to a developing type degradable urethra repairing stent which is prepared from the following components of 50 to 100 weight parts of a degradable medical material A, 0.1 to 50 weight parts of a healing repairing material B, 0.001 to 0.05 weight part of a developing agent C, 0.001 to 0.05 weight part of an anti-hyperuricemia medicine D and 0.001 to 0.05 weight part of vitamins. The developing type degradable urethra repairing stent is extremely high in biocompatibility, and the shape and the position of an implanted material can be quickly judged; the degradation time is controllable; in a complicated urethra reconstruction process, the developing type degradable urethra repairing stent achieves the effects of pressure-reducing supporting, drainage, favorability for urethra healing, convenience for observation and postoperative urethra imaging and the like.

Description

technical field [0001] The invention belongs to the field of biomedical materials, and relates to a developing type degradable urethral repair bracket. Background technique [0002] Interventional radiology is a new branch of the field of radiology, and many of its techniques are derived from surgery, adopted and improved by radiologists. [0003] Interventional therapy comes from interventional radiology. It is an emerging treatment method between surgery and internal medicine. It uses X-ray perspective, CT positioning, B-type ultrasound equipment and other medical imaging equipment as guidance to guide special catheters or instruments through human arteries, The veins, the natural pipeline of the digestive system, the urethra or the drainage pipeline after surgery reach the diseased area in the body to obtain tissue cells, bacteria or biochemical data, and can also perform radiography to obtain imaging data, so as to achieve the purpose of diagnosing the disease. Various ...

Claims

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Application Information

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IPC IPC(8): A61L31/14A61L31/16A61L31/18A61L31/06A61L31/04
CPCA61L31/042A61L31/06A61L31/14A61L31/148A61L31/16A61L31/18A61L2300/236A61L2300/412A61L2300/428A61L2300/432C08L87/005C08L5/08
Inventor 潘学理全志伟
Owner 青岛蓝博云健康产业发展有限公司
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