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Pharmaceutical composition for treating thyroid nodule and preparation method thereof

A technology of thyroid nodules and composition, which is applied in the field of traditional Chinese medicine, can solve problems such as side effects, and achieve the effect of rigorous prescription, avoiding inconvenience of taking, and reducing the score of high-risk factors

Inactive Publication Date: 2016-08-03
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many researches on the treatment of thyroid nodules in modern medicine, and the diagnosis and treatment methods emerge in endlessly, especially with the development of interventional techniques such as radiofrequency ablation and microwave ablation in recent years, the treatment methods of thyroid nodules have been enriched. There is a certain proportion of side effects, so there is still an endless stream of patients who require conservative treatment clinically, and there are still few studies on the treatment of thyroid nodules with traditional Chinese medicine. Therefore, it is still necessary to provide treatment options for clinical diagnosis and treatment of this disease

Method used

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  • Pharmaceutical composition for treating thyroid nodule and preparation method thereof
  • Pharmaceutical composition for treating thyroid nodule and preparation method thereof
  • Pharmaceutical composition for treating thyroid nodule and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0038] Embodiment 1 capsule

[0039] Prescription: 9 parts of kumquat leaves, 18 parts of jasmine flowers, 10 parts of amaranth, 9 parts of water fennel, 10 parts of angelica, 12 parts of egg balm, 2.5 parts of woody fragrance, 12 parts of heterophylla, 16 parts of centipede, 10 parts of Qiongzhi , 6 parts of white mustard seeds.

[0040] Preparation method: (1) Take kumquat leaves, water fennel, woody, frangipani and grind them into particles with an average particle size of 30-40 μm, add 7 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction for 2 times. After the ultrasonic extraction is completed, Take the filtrate, concentrate it under reduced pressure to form a thick paste, and obtain extract A for future use, wherein the extraction conditions include: ultrasonic power of 130-140W, extraction temperature of 30-50°C, and extraction time of 40-50min;

[0041] (2) Grind amaranth, angelica, egg bulwark, heterophylla heterophylla, centipede, qiongz...

Embodiment 2

[0042] Embodiment 2 capsules

[0043] Prescription: 8 parts of kumquat leaves, 18 parts of jasmine flowers, 12 parts of amaranth, 6 parts of water fennel, 10 parts of angelica, 15 parts of egg balm, 3 parts of woody fragrance, 15 parts of heterophylla, 15 parts of centipede, 8 parts of Qiongzhi , 6 parts of white mustard seeds.

[0044] Preparation method: (1) Take kumquat leaves, water fennel, woody, frangipani and grind them into particles with an average particle size of 20-30 μm, add 8 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction for 2 times. After the ultrasonic extraction is completed, Take the filtrate, concentrate it under reduced pressure to form a thick paste, and obtain extract A, which is used for future use. The extraction conditions include: ultrasonic power of 150-160W, extraction temperature of 30-50°C, and extraction time of 20-40min;

[0045] (2) Grind amaranth, angelica, egg bulwark, heterophylla heterophylla, centipede, q...

Embodiment 3

[0046] Embodiment 3 capsules

[0047] Prescription: 12 parts of kumquat leaves, 16 parts of jasmine flowers, 12 parts of amaranth, 8 parts of water fennel, 13 parts of angelica, 13 parts of egg balm, 2 parts of woody fragrance, 10 parts of heterophylla, 18 parts of centipede, 12 parts of Qiongzhi , 5 parts of white mustard seeds.

[0048] Preparation method: (1) Take kumquat leaves, water fennel, woody, frangipani and grind them into particles with an average particle size of 40-50 μm, add 6 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction for 2 times. After the ultrasonic extraction is completed, Take the filtrate, concentrate it under reduced pressure to form a thick paste, and obtain extract A for future use, wherein the extraction conditions include: ultrasonic power of 150-160W, extraction temperature of 30-50°C, and extraction time of 30-40min;

[0049] (2) Grind amaranth, angelica, egg bulwark, heterophylla, mountain hundred foot, Qiongzh...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a pharmaceutical composition for treating a thyroid nodule and a preparation method thereof. The pharmaceutical composition is prepared through elaborate development by taking leaves of oval kumquat, whole plants of jasminum polyanthum Franch., herb of ammannia auriculata Willd., all-grass of winkled marshweed, radix angelicae sinensis, all-grass of canton speranskia, radix aucklandiae, radix pseudostellariae, rhizomes and roots of peliosanthes minor yamamoto, eucheuma gelatinae(Esp.)J.Ag. and white mustard seeds as medicinal materials, the pharmaceutical composition has the effects of soothing the liver, invigorating the spleen, promoting qi, removing stasis, resolving phlegm and dissipating blood stasis and has the effects of warming meridians, promoting qi and promoting blood circulation to remove meridian obstruction simultaneously, multi-system and multifunctional regulation is achieved for a syndrome of hepatic qi stagnation of a patient with the thyroid nodule, the traditional Chinese medicine symptoms can be significantly improved, the high risk factor score is lowered, the nodule is shrunk, and the curative effect is significant.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating thyroid nodules and a preparation method thereof. Background technique [0002] The incidence of thyroid diseases has been increasing in recent years, among which thyroid nodules and hyperthyroidism are the two most common thyroid diseases. Thyroid nodules refer to lumps in the thyroid gland, which can move up and down with the thyroid gland with swallowing actions. It is a common clinical disease and can be caused by a variety of etiologies. According to the classification of nodules, thyroid nodules include benign nodules and malignant nodules. . These two types of nodules are very difficult to distinguish from clinical symptoms. At present, there is no drug with definite efficacy for the treatment of thyroid nodules in the "Guidelines for the Prevention and Treatment of Thyroid Diseases in China". Now L-T4 is ...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P5/14A61P43/00
CPCA61K36/75A61K36/05A61K36/185A61K36/232A61K36/285A61K36/31A61K36/36A61K36/37A61K36/47A61K36/63A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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