Medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies

A technology for recurrent miscarriage and anti-cardiolipin, applied in drug combinations, sexual diseases, pharmaceutical formulations, etc., can solve problems such as lack of safe and effective methods, intracranial hemorrhage, and elevated blood sugar, so as to improve immune function and patient compliance. Good effect with few side effects

Inactive Publication Date: 2016-07-20
徐美英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the treatment of ACA-positive pregnant women is generally divided into two aspects. On the one hand, the purpose of suppression and removal is to use adrenocortical hormone or a large amount of immunoglobulin (such as β-glycoprotein), or plasma exchange therapy, but it will cause Adverse reactions such as increased blood sugar, osteoporosis, and infection; on the other hand, anticoagulant therapy for the purpose of preventing thrombosis, often using heparin or aspirin, but long-term use can cause bleeding tendency, thrombocytopenia, and allergies reaction and possible postnatal intracranial hemorrhage
Therefore, Western medicine still lacks safe and effective methods for the treatment of ACA-positive miscarriage.

Method used

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  • Medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies
  • Medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 capsule

[0036] Prescription: 20 parts of dodder, 8 parts of epimedium, 15 parts of Rehmannia glutinosa, 15 parts of Caragana safflower, 7 parts of cistanche, 15 parts of black cortex root, 6 parts of Eucommia, 12 parts of heart-protecting grass, 10 parts of motherwort, golden silk Akebia 10 parts.

[0037] Preparation method: take the prescribed amount of black cortex root, sycamore and extract with ethanol twice, each time for 1-2 hours, combine the extracts, filter, recover ethanol from the filtrate, concentrate under reduced pressure to form a thick paste, dry, pulverize, and obtain dried Cream powder, spare. Take Cuscuta, Epimedium, Rehmannia glutinosa, Caragana safflower, Cistanche, Eucommia, Motherwort, and Akebia in the prescribed amount, add water to decoct twice, and add water for the first time to 5% of the total amount of medicinal materials taken in this step -8 times, decoct for 2-3 hours, add water for the second time 3-4 times the total a...

Embodiment 2

[0038] Embodiment 2 capsules

[0039] Prescription: 20 parts of Cuscuta, 10 parts of Epimedium, 18 parts of Rehmannia glutinosa, 12 parts of Caragana safflower, 5 parts of Cistanche, 10 parts of black cortex, 7 parts of Eucommia, 15 parts of Huxincao, 8 parts of motherwort, golden silk Akebia 12 parts.

[0040] Preparation method: carry out with reference to Example 1.

Embodiment 3

[0041] Embodiment 3 capsules

[0042] Prescription: 18 parts of dodder, 10 parts of epimedium, 15 parts of Rehmannia glutinosa, 15 parts of Caragana safflower, 8 parts of cistanche, 10 parts of black root, 5 parts of Eucommia, 10 parts of heart-protecting grass, 7 parts of motherwort, golden silk Akebia 12 parts.

[0043] Preparation method: carry out with reference to Example 1.

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and relates to a medicine composition for treating recurrent abortion due to positive anticardiolipin antibodies and a method for preparing the medicine composition. The medicine composition comprises semen cuscutae, herba epimedii, radix rehmanniae preparata, caragana rosea, herba cistanches, roots of polyalthia nemoralis, cortex eucommiae, cyperus michelianus, herba leonuri and clematis chrysocoma. The medicine composition and the method have the advantages that all components of the medicine composition are compatible with one another, accordingly, effects of nourishing kidneys, enriching qi and promoting blood circulation to remove blood stasis can be realized, congenital and postnatal attributes can be jointly nourished, yin and yang in the kidneys can be regulated and invigorated again to be in balance, and definite curative effects of reducing or eliminating the serum anticardiolipin antibodies can be realized; symptoms of kidney deficiency and blood stasis of patients who suffer from excessive maternal-fetal immune recognition type recurrent spontaneous abortion can be treated, the obvious curative effects can be realized, and the medicine composition is free of side effects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating recurrent miscarriage caused by anticardiolipin antibody positive and a preparation method thereof. Background technique [0002] Recurrent spontaneous abortion (RSA) is a common pregnancy complication, which refers to the spontaneous abortion of two or more fetuses with the same spouse before 28 weeks of pregnancy. The etiology and pathogenesis of this disease are quite complex, and immune factors are also one of the important reasons. Phospholipids are ubiquitous in the human body and are essential components of the placenta and villi. Antiphospholipid antibodies (antiphospholipidantibodies, APA) are antibodies that can react with a variety of antigenic substances containing phospholipid structures, which mainly include anticardiolipin antibodies (anticardiolipinantibody, ACA). [0003] Anticardiolipin antibodies ar...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P15/06
CPCA61K36/39A61K36/185A61K36/296A61K36/46A61K36/48A61K36/533A61K36/64A61K36/716A61K36/804A61K36/8905A61K2236/33A61K2236/331A61K2236/39A61K2300/00
Inventor 徐美英
Owner 徐美英
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