Animal experimental device for precision radiotherapy research

Abstract

The invention belongs to the technical field of medical apparatus and instruments, and discloses an animal experimental device for precision radiotherapy research.The animal experimental device comprises a C-shaped structure rotation platform and a carrying movement platform.The rotation central axis of the C-shaped structure rotation platform perpendicularly intersects with the rotation central axis of the carrying movement platform.The C-shaped structure rotation platform comprises a C-shaped support with a translation device, an X-ray optical source with optical gratings, a cone-beam CT (computed tomography) imaging detector, a SPECT (single photon emission computed tomography) imaging detector and a rotation driving device.The animal experimental device has the advantages that human precision radiotherapy procedures can be accurately simulated by the aid of the animal experimental device, and the animal experimental device has structure and function precision imaging real-time guidance, objective target region precision irradiation functions and the like, is a novel radiotherapy scientific research simulation platform with integrated high-precision positioning, high-precision multi-modal structure and function image guidance and high-precision multi-mode inverse radiotherapy planning, and is applicable to radiation oncology preliminary clinical research in preliminary clinical research application places such as tumor formation and development mechanisms, radiotherapy response and tumor and normal tissue radiobiological effects.

Description

technical field [0001] The present invention relates to a device in the technical field of medical devices, in particular to an animal experiment device for precision radiotherapy research. Background technique [0002] Radiation therapy (RT), as an effective and cost-effective means of cancer treatment, is a vital and integral part of the comprehensive treatment of tumors. With its advantages of side effects and less damage to patients, precision radiotherapy has partially replaced the previous tumor treatment that used surgery as the main treatment. Pre-clinical research is an indispensable part of the theoretical research of new radiotherapy. The main reason is that the ionizing radiation produced by high-energy rays can cause great damage to normal tissues. The theoretical research needs to be fully verified in the pre-clinical environment before entering human clinical trials. Perform radiation therapy simulations on ex vivo and living samples to verify theoretical rel...

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Problems solved by technology

[0003] Aiming at the above-mentioned deficiencies in the prior art, the present invention provides an animal experiment device for precision radiation therapy research, which solves the problems of mismatch between precision radiation therapy animal experiment and clinical application, lack of real-time image guidance, etc., and has the ability to accurately simulate human body precision radiation therapy The characteristics of real-time guidance of precise images of process, structure and function, and precise irradiation of target areas have important applications for preclinical research on radiation oncology, such as tumor generation and development mechanism, treatment response, tumor and normal tissue radiobiological effects, etc. value

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