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Traditional Chinese medicine for treating acute radiation pneumonitis and preparation method of traditional Chinese medicine

A radiation pneumonitis and traditional Chinese medicine technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of immunosuppression-induced superinfection, etc., and achieve good therapeutic effect, quick effect, no toxic side effects and Effects of adverse reactions

Inactive Publication Date: 2016-07-06
刘鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, large doses of adrenal glucocorticoids combined with antibiotics are mainly used in the treatment of acute radiation pneumonitis at home and abroad. Although large doses of corticosteroids can temporarily relieve symptoms and inhibit the development of pulmonary fibrosis, but because of related side effects, such as immunosuppression, induced double Infection, hyperglycemia, withdrawal syndrome, swollen

Method used

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Examples

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Effect test

preparation example Construction

[0044] When the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0045] In the first step, the raw medicinal materials are mixed in proportion, put into a casserole and fried for 30-60 minutes, crushed into fine powder with a pulverizer, and sieved into a powder of 100-200 mesh;

[0046] In the second step, add ethanol with an alcohol concentration of 85% to 95% that is 4 to 6 times the mass of the powder obtained in the first step, heat and reflux for 2 to 4 hours, extract 2 to 3 times, combine the extracts, and filter to obtain the alcohol The extract, the alcohol extract is concentrated under reduced pressure, and recovered until there is no alcohol smell; the dregs obtained by filtering are added to distilled water 2 to 5 times the quality of the filter residue, and decocted for 1 to 3 hours each time, and decocted for 2 to 3 times , filtered respectively, combined the filtrates to obtain a water extract, concent...

Embodiment 1

[0057] Embodiment 1: capsules prepared by the present invention

[0058]Take 260g of Radix Radix Root, 150g of Throat Grass, 210g of Rock Onion, 150g of Artemisia sativa, 260g of Prunus chinensis, 380g of Coriander, 70g of Acanthopanax, 290g of Calendula, 160g of Sea Fen, 90g of Golden Chicken Feet, 190g of Soybean Yellow Roll, 120g, chrysanthemum chrysanthemum 290g, cone flower 210g and beech flower 350g.

[0059] Its preparation method comprises the following steps:

[0060] When the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0061] In the first step, the raw medicinal materials are mixed in proportion, put into a casserole and fried for 50 minutes, crushed into fine powder with a pulverizer, and sieved into a 200-mesh powder;

[0062] In the second step, add ethanol with an alcohol concentration of 90% that is 6 times the mass of the powder obtained in the first step, heat and reflux for 4 hours, extract t...

Embodiment 2

[0067] Embodiment 2: the syrup prepared by the present invention

[0068] Take 290g of Radix Radix Root, 120g of Throat Grass, 250g of Rock Onion, 120g of Artemisia sativa, 290g of Peach Fungus, 360g of Prunus chinensis, 90g of Acanthopanax, 260g of Calendula, 190g of Sea Fen, 70g of Golden Chicken Feet, 160g of Soybean Yellow Rolls, 150g, chrysanthemum chrysanthemum 260g, cone flower 250g and beech flower 320g.

[0069] Its preparation method comprises the following steps:

[0070] In the first step, mix Radix Radix Rhizome, Throat Grass, Rock Onion, Artemisia Sinensis, Seven Pterocarpus and Cortex Cortex in the stated ratio, add ethanol whose alcohol concentration is 85% relative to the mixture 6 times, heat and reflux for extraction 3 times, each time Reflux for 3 hours, combine the extracts, and centrifuge to remove impurities with a tube centrifuge. Concentrate the removed extracts under reduced pressure at 65°C to a medicinal solution with a relative density of 1.06 at ...

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Abstract

The invention provides a traditional Chinese medicine for treating acute radiation pneumonitis and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine is prepared from the following medicinal materials: rubus ellipticus smith, umbellate rock jasmine, clavateleaf oberonia herb, integrifolia, radix podophylli, sagittaria guyanensis, trifoliate acanthopanax root root-bark, calendula officinalis, dried sea hare ovary, phymatopsis hastate, semen sojae germinatum, campsis radicans, flaccid aster, gomphostemma roots and caudate sweetleaf flowers. The traditional Chinese medicine has the beneficial effects that the traditional Chinese medicine is matched with a western conventional method to treat the acute radiation pneumonitis, so that the traditional Chinese machine is convenient to use, relatively good in treatment effect, free of toxic or side effect or bad reaction, fast to take effect and simple in preparation technology.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine for treating acute radiation pneumonitis and a preparation method thereof. Background technique [0002] Acute radiation pneumonitis is an inflammatory reaction caused by damage to normal lung tissue in the radiation field after radiation therapy for lung, mediastinum, tumor, esophageal cancer, breast cancer, malignant lymphoma or other tumors in the chest. Mild cases are asymptomatic, and the inflammation dissipates spontaneously; severe cases develop extensive pulmonary fibrosis, leading to respiratory function damage and even respiratory failure. [0003] Mild cases are asymptomatic. An irritating cough can occur immediately after radiation therapy, most of which appear 2 to 3 months after radiation therapy, and a few have an irritating dry cough half a year after stopping radiation therapy, which is exacerbated ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P11/00A61K35/618
CPCA61K36/898A61K9/0095A61K9/4866A61K35/618A61K36/11A61K36/185A61K36/254A61K36/28A61K36/282A61K36/29A61K36/48A61K36/53A61K36/73A61K36/884A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘鹏
Owner 刘鹏
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