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Gynecological capsule

A capsule, gynecological technology, applied in the directions of capsule delivery, anti-inflammatory agent, non-central analgesic, etc., can solve the problem of women's dysmenorrhea and other problems that have not been fundamentally solved, and achieve no toxic side effects, significant effect, and high extraction rate. Effect

Inactive Publication Date: 2016-06-15
王玉芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing western medicines for treating dysmenorrhea include: indomethacin, mefenamic acid, ibuprofen, pylorixikon, naproxen, diclofenac, etc., all of which are temporary pain relievers and have not fundamentally solved the problem of female dysmenorrhea. question

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: the preparation of a kind of capsule for treating gynecology

[0029] Contains the following raw materials in parts by weight: 15 parts of motherwort extract, 20 parts of angelica extract, 20 parts of herb extract, 10 parts of Caulis Spatholobus extract, 24 parts of disintegrating agent, 10 parts of surfactant, 35 parts of sorbitol, 5 parts of magnesium stearate; Disintegrant is polyvinylpyrrolidone and microcrystalline cellulose, surfactant is nonylphenol polyoxyethylene ether and poloxamer; The weight ratio of polyvinylpyrrolidone and microcrystalline cellulose is 3: 1. The weight ratio of nonylphenol polyoxyethylene ether to poloxamer is 2:3;

[0030] The preparation method comprises the following steps:

[0031] (1) Ultrafinely pulverize the motherwort medicinal material to a particle size of 100 μm, put it in a dynamic extraction tank, add 10 times the amount of 75% ethanol solution, extract at 60°C for 40 minutes, and filter to obtain the extract; t...

Embodiment 2

[0036] Embodiment 2: the preparation of a kind of capsule for treating gynecology

[0037] Contains the following raw materials in parts by weight: 20 parts of motherwort extract, 25 parts of angelica extract, 20 parts of herb extract and 10 parts of Caulis Spatholobus extract, 28 parts of disintegrating agent, 15 parts of surfactant, 40 parts of lactose, micropowder 6 parts of silica gel; and the disintegrating agent is polyvinylpyrrolidone and microcrystalline cellulose, and the surfactant is nonylphenol polyoxyethylene ether and poloxamer; the weight ratio of polyvinylpyrrolidone and microcrystalline cellulose is 3:1, The weight ratio of nonylphenol polyoxyethylene ether and poloxamer is 2:3;

[0038] The preparation method of Motherwort extract and Angelica sinensis extract is the same as in Example 1, commercially available products are used for Atractylodes atractylodes extract and Caulis Spatholobus extract, and the others are the same as in Example 1.

Embodiment 3

[0039] Embodiment 3: a kind of preparation of treating gynecology capsule

[0040] Contains the following raw materials in parts by weight: 10 parts of motherwort extract, 15 parts of angelica extract, 10 parts of herb extract, 5 parts of Caulis Spatholobus extract, 16 parts of disintegrating agent, 10 parts of surfactant, 30 parts of cornstarch, 3 parts of talcum powder; and the disintegrating agent is polyvinylpyrrolidone and microcrystalline cellulose, and the surfactant is nonylphenol polyoxyethylene ether and poloxamer; the weight ratio of polyvinylpyrrolidone and microcrystalline cellulose is 3:1 , the weight ratio of nonylphenol polyoxyethylene ether and poloxamer is 2:3;

[0041] Motherwort extract, Angelica sinensis extract, Atractylodes atractylodes extract and Caulis Spatholobus extract were commercially available products, and the others were the same as in Example 1.

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Abstract

The invention relates to a gynecological capsule. The gynecological capsule comprises a herba leonuri extract, an angelica sinensis extract, a rhizoma atractylodis extract and a caulis spatholobi extract; a disintegrating agent is prepared from polyvinylpyrrolidone and microcrystalline cellulose; a surfactant is prepared from nonylphenol polyoxyethylene ether and poloxamer; moreover, and a filling agent and a lubricating agent are contained. The herba leonuri, the angelica sinensis, the rhizoma atractylodis and the caulis spatholobi are combined with each other, so that the gynecological capsule has the effects of nourishing Qi and blood, enriching yin, nourishing kidney, and promoting qi circulation to relieve pain; meanwhile, Chinese medicinal materials are subjected to specific extraction processes such as dynamic extraction, ultra-critical extraction and macroporous adsorption resin column chromatography, so that the gynecological capsule has remarkable effects in treating irregular menstruation and dysmenorrhea of women, and has no toxic or side effects.

Description

technical field [0001] The invention relates to a capsule, in particular to a gynecological capsule, in particular to a gynecological capsule for treating irregular menstruation and dysmenorrhea. Background technique [0002] Irregular menstruation, also known as menstrual disorders, is a common gynecological disease, manifested as abnormal menstrual cycle or bleeding, or abdominal pain and systemic symptoms before and during menstruation. Hormone imbalance, long-term mental depression, mental stress or suffering from major mental stimulation and trauma, cold stimulation, dieting and other reasons can lead to irregular menstruation in women. According to the survey and statistics of the Ministry of Health, the incidence rate of gynecological diseases in my country is as high as 75%, among which patients with irregular menstruation and dysmenorrhea account for about 50%. Irregular menstruation can cause various gynecological diseases, and even indirectly lead to other malign...

Claims

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Application Information

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IPC IPC(8): A61K36/533A61K9/48A61K47/32A61K47/38A61K47/34A61P15/00A61P29/00
CPCA61K36/533A61K9/4866A61K36/232A61K36/284A61K36/486A61K2236/333A61K2236/37A61K2236/55A61K2300/00
Inventor 王玉芹
Owner 王玉芹
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