Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for improving surface bioactivity of polyether ether ketone

A polyetheretherketone, bioactive technology, applied in tissue regeneration, pharmaceutical formulations, drug delivery and other directions, can solve the problems of easy detachment of the coating, cumbersome preparation process, complicated preparation instruments, etc., and achieves improved mechanical properties, simple process, Excellent performance

Inactive Publication Date: 2016-05-04
SHANGHAI JIAO TONG UNIV
View PDF4 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation equipment used for these coatings is complex and the preparation process is cumbersome, and the prepared biological coating cannot form a strong combination with PEEK, and the coating is often easy to fall off during clinical application.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for improving surface bioactivity of polyether ether ketone
  • Method for improving surface bioactivity of polyether ether ketone
  • Method for improving surface bioactivity of polyether ether ketone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Medical-grade titanium wire with a diameter of 0.005 mm is used to prepare porous titanium with a set shape and porosity by winding machinery, and its porosity is 45%. Infiltration technology forms a layer of 2mm porous titanium layer on the surface of PEEK. The strength of the modified PEEK is 180MPa, and the adhesion strength of the coating is 80MPa. It is suitable for intervertebral cages and other occasions.

Embodiment 2

[0034] The medical-grade titanium-tantalum alloy wire with a diameter of 3mm is used to prepare a porous metal with a set shape and porosity by winding machinery. The porosity is 10%. The porous metal is made of twin-screw extrusion and molding technology Embed PEEK to form a 3mm porous metal layer on the surface. The strength of the modified PEEK is 150MPa, and the adhesion strength of the coating is 210MPa. It is suitable for femoral stems and other occasions.

Embodiment 3

[0036] The medical grade 316L stainless steel wire with a diameter of 0.27mm is used to prepare a porous metal with a set shape and a set porosity by winding machinery. The porosity is 71%. During the process of PEEK polycondensation, the porous stainless steel is embedded. In PEEK, a 1mm porous stainless steel layer is formed on the surface. The strength of the modified PEEK is 120MPa, and the adhesion strength of the coating is 160MPa, which is suitable for acetabular cups and other occasions.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
strengthaaaaaaaaaa
porosityaaaaaaaaaa
Login to View More

Abstract

The invention provides a method for improving surface bioactivity of polyether ether ketone (PEEK). The method is characterized in that in a PEEK preparation process or a PEEK re-formation process, a porous metal layer with excellent biocompatibility is embedded in the surface of PEEK, thereby obtaining a porous fiber / PEEK composite material; the structure of the composite material is that the surface is a bioactivity coating, and the base is a composite material of the metal porous layer and the PEEK. The method provided by the invention integrates PEEK surface modification and PEEK preparation; the method is simple and has low requirements on instruments. The prepared novel composite material has excellent performances, the bioactivity of the PEEK is improved, bone conduction and body fluid transmission are facilitated, the mechanical property and osteogenesis efficiency are improved, and the prepared composite material has stronger binding force between the porous metal layer and the PEEK so as to meet most application requirements, such as bone filling, bone repair, bone transplantation and bone fixation, and in particular the composite material can be applied to bone transplantation under loading conditions, such as interbody fusion cage, vertebral replacement, femoral head diseases, acetabular cup, fixing bolt and fixing plate.

Description

technical field [0001] The invention relates to a medical biocomposite material, in particular to a method for improving the biological activity of a polyether ether ketone (PEEK) material surface, and belongs to the technical field of biomedical materials. Background technique [0002] Polyether ether copper (PEEK) is a new type of organic polymer compound, which has the advantages of radiation translucency and elastic modulus between cancellous bone and compact bone. have been widely applied. However, as a biologically inert material, PEEK is difficult to form bone fusion with human bones, which limits its application as a bone repair material. In response to this deficiency, many scholars have applied different methods to process PEEK to improve its osteogenic performance; including: PEEK-hydroxyapatite (HA) composite material, PEEK-HA-carbon fiber composite material, nano-fluoroapatite-PEEK Composite materials, nano-titanium dioxide-PEEK composite materials, etc. Howe...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/40A61L27/18A61L27/30A61L27/56
CPCA61L27/18A61L27/306A61L27/56A61L2400/18A61L2430/02
Inventor 何国江国锋
Owner SHANGHAI JIAO TONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com