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Application of moroxydine in preparing myocardial infarction therapeutic drug

A technique for myocardial infarction and a drug for treating myocardial infarction is applied to the new medical use of morpholine guanidine. The application field of morpholine guanidine for preparing a drug for treating myocardial infarction can solve the problems of poor efficacy of the drug for treating myocardial infarction and the like, and achieve a reduction in serum muscle mass. Acid kinase activity, regulation of vascular tone, significant curative effect

Inactive Publication Date: 2016-04-06
朱孟允
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0005] The present invention aims at the technical defects of the prior art, and provides the application of morpholine guanidine for the preparation of drugs for the treatment of myocardial infarction, so as to solve the technical problem of poor curative effect of the drugs for the treatment of myocardial infarction in the prior art

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  • Application of moroxydine in preparing myocardial infarction therapeutic drug
  • Application of moroxydine in preparing myocardial infarction therapeutic drug
  • Application of moroxydine in preparing myocardial infarction therapeutic drug

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Embodiment Construction

[0015] Specific embodiments of the present invention will be described in detail below. In order to avoid too many unnecessary details, well-known structures or functions will not be described in detail in the following embodiments.

[0016] Approximate language used in the following examples is for quantitative representations, indicating that certain variations in quantities are permissible without altering essential function. Accordingly, values ​​modified by language such as "about", "approximately" and the like are not limited to the exact value itself. In some embodiments, "about" means that the corrected value is allowed to vary within the range of plus or minus ten percent (10%), for example, "about 100" means any value between 90 and 110. Furthermore, in the expression "about the first value to the second value", both values ​​of the first value and the second value are corrected approximately at the same time. In some cases, the language of approximation may relate...

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Abstract

The invention provides application of moroxydine in preparing a myocardial infarction therapeutic drug. According to the application of the moroxydine in preparing the myocardial infarction therapeutic drug, the regulating effect of the moroxydine on the cardiovascular system is examined through an experimental method, and the fact that the moroxydine can reduce blood viscosity, reduce serum creatine kinase activity and reduce thromboxane A2 (TXA2) level in plasma and also can up-regulate prostacyclin (PGI2) level in the plasma and improve serum superoxide dismutase (SOD) activity, so as to regulate angiotasis and promote blood fluidity is innovatively found. On the basis of the new properties of the moroxydine, by using the moroxydine as the myocardial infarction therapeutic drug, a protection effect on myocardial ischemic reperfusion damage can be realized, and cerebral infarction volume is reduced, so as to realize the treatment for myocardial infarction. The application provided by the invention is significant in drug therapeutic effect, rapid in effect and free of side effect, clinical experiments show that a higher cure rate is realized, and a huge popularization prospect is realized.

Description

technical field [0001] The invention relates to the technical field of cardiovascular disease treatment, and further relates to the new medical application of morpholine guanidine, in particular to the application of morpholine guanidine in the preparation of drugs for treating myocardial infarction. Background technique [0002] Acute myocardial infarction is myocardial necrosis caused by acute and persistent coronary ischemia and hypoxia. Clinically, there are often severe and persistent substernal pains, which cannot be completely relieved by rest and nitrates, accompanied by increased serum myocardial enzyme activity and progressive ECG changes, which may be complicated by arrhythmia, shock or heart failure, often life-threatening. The harm of myocardial infarction is not only the disease itself, but also often accompanied by fatal complications, such as myocardial infarction loss of elasticity, necrosis, enzymatic lysis caused by the release of hydrolytic enzymes by neu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/5375A61P9/10
CPCA61K31/5375
Inventor 朱孟允
Owner 朱孟允
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