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Traditional Chinese medicine composition for promoting wound healing and preparation method of traditional Chinese medicine composition

A technology of wound healing and composition, which is applied in the field of traditional Chinese medicine composition promoting skin wound healing and its preparation, and can solve problems such as hypertrophic scars, canceration, and complex compatibility

Inactive Publication Date: 2015-12-30
QINGDAO MERRITT MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although some growth factors have a strong effect of promoting cell proliferation and can promote wound healing, but because wound healing requires the participation of multiple growth factors, the compatibility is complex, and its safety has always been the focus of attention. However, excessive cell proliferation may lead to proliferation. Sexual scars, and even cause cancer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] Prescription: 25 parts of Zi Zhu Ye, 20 parts of Polygonum sp., 17 parts of Ghost Needle, 10 parts of Dipsacus, 8 parts of Impatiens Sperantospermum, 15 parts of Scutellaria, 10 parts of Baiji, 16 parts of lanolin, Vaseline 640 parts, 2 parts of ethyl p-hydroxybenzoate.

[0086] Preparation method: (1) Pulverize Polygonum sp., reflux extract with 70% ethanol for 3 times, each time for 1.5 hours, combine the 3 extracts, concentrate under reduced pressure to obtain a dilute extract, put it on a polyamide column, and first use 20% Elute with ethanol until the effluent is colorless, then elute with 90% ethanol, collect the ethanol eluate, recover the ethanol under reduced pressure until it has no alcohol smell, and continue to concentrate to a clear paste with a relative density of 1.13 (measured at 60°C);

[0087] (2) Add water to decoct Zizhuye, Guizhencao, Dipsacus, Impatiens Tugucao, Scutellaria, Baiji and add water for two times, add water for the first time to 4-8 tim...

Embodiment 2

[0090] Prescription: 30 parts of Zi Zhu Ye, 18 parts of Polygonum sp., 15 parts of Ghost Needle Grass, 8 parts of Dipsacus, 9 parts of Impatiens Sperancis, 17 parts of Scutellaria, 12 parts of Bai Ji, 160 parts of lanolin, Vaseline 650 parts, 2 parts of ethyl p-hydroxybenzoate.

[0091] Preparation method: (1) Pulverize Polygonum sp., reflux extract with 70% ethanol for 3 times, each time for 1.5 hours, combine the 3 extracts, concentrate under reduced pressure to obtain a dilute extract, put it on a polyamide column, and first use 20% Elute with ethanol until the effluent is colorless, then elute with 90% ethanol, collect the ethanol eluate, recover the ethanol under reduced pressure until it has no alcohol smell, and continue to concentrate to a clear paste with a relative density of 1.10 (measured at 60°C);

[0092] (2) Add water to decoct Zizhuye, Guizhencao, Dipsacus, Impatiens Tugucao, Scutellaria, Baiji and add water for two times, add water for the first time to 4-8 ti...

Embodiment 3

[0095] Prescription: 27 parts of Zi Zhu Ye, 20 parts of Polygonum sp., 15 parts of Ghost Needle Grass, 12 parts of Dipsacus, 5 parts of Impatiens Sperantospermum, 20 parts of Cystaceae, 12 parts of Bai Ji, 150 parts of lanolin, Vaseline 650 parts, 1.5 parts of ethyl p-hydroxybenzoate.

[0096] Preparation method: (1) Pulverize Polygonum sp., reflux extract with 70% ethanol for 3 times, each time for 1.5 hours, combine the 3 extracts, concentrate under reduced pressure to obtain a dilute extract, put it on a polyamide column, and first use 20% Elute with ethanol until the effluent is colorless, then elute with 90% ethanol, collect the ethanol eluate, recover the ethanol under reduced pressure until it has no alcohol smell, and continue to concentrate to a clear paste with a relative density of 1.15 (measured at 60°C);

[0097] (2) Add water to decoct Zizhuye, Guizhencao, Dipsacus, Impatiens Tugucao, Scutellaria, Baiji and add water for two times, add water for the first time to...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses traditional Chinese medicine composition for promoting wound healing. The traditional Chinese medicine composition is prepared from raw materials including beautyberry leaves, willow-leaved smartweed, Bidens alba, himalayan teasel roots, garden balsam, Rubus phoenicolasius and common bletilla pseudobulb, prepared to form a dosage form for external use, preferably to form an ointment, can be used for dispersing blood stasis, reducing swelling, relieving pain, clearing heat to remove toxicity, resisting bacteria, diminishing inflammations, removing necrotic tissue and promoting granulation, plays multi-target-point, multi-link and multi-level comprehensive regulation and control roles, can accelerate wound granulation growth and promote wound scabbing and healing and has the remarkable curative effect, safety, reliability, freedom from toxic and side effects as well as wide clinical application prospect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for promoting skin wound healing and a preparation method thereof. Background technique [0002] Wound repair is one of the oldest topics in medicine, because there have been traumas since human beings, and there have been wound repairs since there were traumas. At present, the research on it has gone deep into the level of cells, molecules and genes. People have been constantly seeking and exploring drugs and methods that can promote wound healing as soon as possible after trauma. [0003] Local treatment is now one of the main means of treating skin wounds in clinical medicine. Although some protective agents, antibiotics, vitamins, and trace element preparations are widely used, they basically stay in the stage of waiting for the natural healing of wounds, and their effect on promoting wound healing is very li...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61P17/02
Inventor 吴兴连
Owner QINGDAO MERRITT MEDICAL TECH CO LTD
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