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Oral care product containing hickory leaf alcohol extract and having effect of helicobacter pylori

An anti-Helicobacter pylori and pecan leaf technology, applied in the field of daily chemicals, can solve the problems of increasing the difficulty of treating patients and medical costs, not having the effect of killing Helicobacter pylori, and increasing the drug resistance of Helicobacter pylori, etc. Killing Helicobacter pylori, improving the oxidative activity of antibiotics, strong antioxidant and scavenging free radicals

Inactive Publication Date: 2015-12-02
杭州华胄生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The shortcoming of prior art is: 1. Kill a large amount of beneficial bacteria, easily cause disease outbreak repeatedly 2. The taking of multiple antibiotics in large doses has increased the drug resistance of Helicobacter pylori, and bacterial drug resistance makes the original effective antibiotics The treatment effect is reduced or lost, which increases the difficulty of treatment and medical costs for patients
Although there are some Chinese herbal health care toothpastes on the market, the antibacterial effect is not ideal enough, especially it does not have the effect of killing Helicobacter pylori

Method used

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  • Oral care product containing hickory leaf alcohol extract and having effect of helicobacter pylori
  • Oral care product containing hickory leaf alcohol extract and having effect of helicobacter pylori
  • Oral care product containing hickory leaf alcohol extract and having effect of helicobacter pylori

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The toothpaste with anti-helicobacter pylori effect containing hickory leaf alcohol extraction is composed of the following components in parts by weight: 90 parts of calcium hydrogen phosphate, 25 parts of water, 7 parts of sorbitol, 3 parts of hydrated silica, polyethylene glycol -83 parts, propylene glycol 4 parts, sodium lauryl sulfate 2 parts, cellulose gum 3 parts, hydroxyethyl cellulose 3 parts, essence 3 parts, sodium benzoate 3 parts, sodium saccharin 3 parts, hickory leaf alcohol extract 3 copies.

[0030] Wherein, the pecan leaf ethanol extract is prepared by the following method:

[0031] 1) Rinse the hickory leaves with tap water, dehydrate and dry, crush them, and pass through a 60-mesh sieve to obtain hickory leaf powder;

[0032] 2) Add 2000mL of 95% ethanol to 200g of pecan leaf powder according to the material-to-liquid ratio of 1:10 (g / mL), and extract under reflux at 95°C for 0.5h to obtain the extract;

[0033] 3) Filter the extract with filter pa...

Embodiment 2

[0041] The mouthwash with anti-Helicobacter pylori effect containing hickory leaf alcohol extract is composed of the following components in parts by weight: 95 parts of water, 15 parts of sorbitol, 7 parts of propylene glycol, 8 parts of xylitol, PEG-400 polymer 8 parts of ethylene glycol, 3 parts of dimethyl glycyrrhizinate, 3 parts of sodium benzoate, 2 parts of essence, 3 parts of hickory leaf ethanol extract.

[0042] The preparation method of hickory nut leaf ethanol extract is the same as embodiment 1.

Embodiment 3

[0044] The chewing gum with anti-Helicobacter pylori effect containing hickory leaf alcohol extract is composed of the following components in parts by weight: 35 parts of xylitol, 25 parts of gum base, 17 parts of sorbitol, 17 parts of maltitol liquid, D- 8 parts of mannitol, 170 parts of citric acid, 110 parts of phospholipids, 35 parts of aspartame, 35 parts of essence, and 3 parts of ethanol extract of pecan leaves.

[0045] The preparation method of hickory nut leaf ethanol extract is the same as embodiment 1.

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Abstract

The invention discloses an oral care product containing hickory leaf alcohol extract and having effect of helicobacter pylori. The oral care product is characterized by comprising the hickory leaf alcohol extract. The oral care product is a traditional Chinese medicine oral care product; a medicine extraction method is simple, dosage components are stable and directly accessible to the oral cavity; long-term usage of the product never causes oral environment disorders and has no side effect. Like products such as existing herbal health toothpastes, the product is capable of eliminating bad breath, treating oral ulcers and diminishing inflammations by resisting common oral pathogens, and also has the functions of killing helicobacter pylori and effectively preventing oral spreading of helicobacter pylori. In addition, researches discover that hickory leaves contain high-content flavonoid glycosides and have high activity of autoxidation and free radicals elimination, antibiotic oxidability of a product is improved, and shelf life of the product is prolonged.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals, and in particular relates to an oral care product containing hickory leaf ethanol extract and having the effect of resisting Helicobacter pylori. Background technique [0002] Helicobacter pylori, English name Helicobacter pylori, referred to as Hp. Helicobacter pylori is a highly infectious pathogenic bacteria. In 1983, Australian scholars Barry J. Marshall and Robin Warren J. Robin Warren first isolated and detected Helicobacter pylori in gastric mucosal biopsy tissue of gastritis patients. In 1989, Australian scholar Krajden detected HP in the dental plaque of the oral teeth of patients with gastritis, and confirmed that it was the same as Hp in the stomach from the molecular level. Hp is an infectious disease transmitted orally, and oral Hp is an important reservoir of gastric Hp. The damage of Helicobacter pylori to human health is significant: it is the first carcinogen that indu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q11/00A61P31/04A61P31/02A61P1/02
Inventor 严杰林世恩葛玉梅
Owner 杭州华胄生物科技有限公司
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