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Pharmaceutical composition for treating sequela of apoplexy

A technology for stroke sequelae and composition, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve problems such as nerve cell protection, and achieve the effect of reducing the formation of glial scars and achieving significant clinical curative effect.

Inactive Publication Date: 2015-11-25
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] In the existing public technical information, there is no drug based on nerve cell protection to effectively treat the sequelae of stroke

Method used

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  • Pharmaceutical composition for treating sequela of apoplexy
  • Pharmaceutical composition for treating sequela of apoplexy
  • Pharmaceutical composition for treating sequela of apoplexy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of stroke sequelae

[0031] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of stroke sequelae are:

[0032] 55 parts by weight of succulent grass, 25 parts by weight of catalpa pod powder, 15 parts by weight of Stylopodium chinensis and 5 parts by weight of cypress biflavones, 3.5 parts by weight of Cypress biflavones;

[0033] Preparation:

[0034] (1) According to the ratio of raw materials, take catalpa pod powder, zhongyabai, mix well, crush, pass through a 50-mesh sieve, use supercritical carbon dioxide extraction technology, extraction temperature 42 ℃, extraction pressure 28MPa, extraction time 3h, collect and extract product, to obtain extract A;

[0035] (2) According to the ratio of the raw materials, take the succulent grass and Stylophyllum, mix well, use 25% ethanol as the solvent, and extract by warm soak...

Embodiment 2

[0037] Embodiment 2: The pharmaceutical composition and preparation method thereof for the treatment of stroke sequelae

[0038] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of stroke sequelae are:

[0039] 50 parts by weight of catalpa pod powder, 30 parts by weight of catalpa pod powder, 12 parts by weight of cypress chinensis, and 6 parts by weight of cypress biflavones, 3 parts by weight of cypress biflavones;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take catalpa pod powder, Zhongyabai, mix well, crush, pass through a 50-mesh sieve, use supercritical carbon dioxide extraction technology, extraction temperature 42 ℃, extraction pressure 28MPa, extraction time 3h, collect and extract product, to obtain extract A;

[0042](2) According to the ratio of the raw materials, take the succulent grass and Stylophyllum, mix well, use 25% ethanol as the solvent, and extract by warm soaking...

Embodiment 3

[0044] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of stroke sequelae

[0045] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of stroke sequelae are:

[0046] 60 parts by weight of catalpa pod powder, 20 parts by weight of cypress pod powder, 18 parts by weight of Stylophyllum chinensis, 4 parts by weight of cypress biflavones, 4 parts by weight of cypress biflavones;

[0047] Preparation:

[0048] (1) According to the ratio of raw materials, take catalpa pod powder, Zhongyabai, mix well, crush, pass through a 50-mesh sieve, use supercritical carbon dioxide extraction technology, extraction temperature 42 ℃, extraction pressure 28MPa, extraction time 3h, collect and extract product, to obtain extract A;

[0049] (2) According to the ratio of the raw materials, take the succulent grass and Stylophyllum, mix well, use 25% ethanol as the solvent, and extract by warm soaki...

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PUM

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Abstract

The present invention discloses a pharmaceutical composition for treating sequela of apoplexy. The pharmaceutical composition uses Lancea tibetica, kamalatree pericarpial glandular hairs, Lomatogonium carinthiacum, tuber salep, amentoflavone, and hinokiflavone as crude drugs for proportioning. A supercritical extraction and an optimized modern extraction process are employed, and the pharmaceutical composition can be prepared into various dosage forms according to conventional formula process. The present invention overcomes the deficiencies of the prior art, and provides a safe significantly effective pharmaceutical composition for treating sequela of apoplexy.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating stroke sequelae. Background technique [0002] With the aging population in our country and the increasingly fierce social competition, cardiovascular diseases are increasing and the incidence of stroke is getting higher and higher. Patients with stroke sequelae not only suffer from pain and torture, which seriously affect the quality of life of patients, but also bring a lot of burden and pressure to society and family. Stroke sequelae refer to the symptoms left over after the treatment of the acute stage of stroke. The pathogenesis of apoplexy sequelae is mostly characterized by deficiency in origin and excess in superficiality, and a mixture of deficiency and excess. The location of the disease is not only in the meridians and blood vessels, but also closely related to the liver, spleen and kidney. [0003] After the occ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P9/10
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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