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Traditional Chinese medicine patch for preventing piglet diarrhea as well as preparation method and application thereof

A technology of piglet diarrhea and traditional Chinese medicine paste, which is applied in the direction of medical formula, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as high drug residues in pork food, unsuitable for large-scale production, and anorexia reaction in piglets. Achieve the effects of improving and regulating the state of the body, promoting the development of digestive organs, and improving the immunity of piglets

Inactive Publication Date: 2015-08-19
DALIAN NATIONALITIES UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicines that add chemicals or antibiotics to the feed are mostly used to prevent diarrhea in piglets. However, with the continuous emergence of drug-resistant strains and the poor resistance of piglets, the mainstream Western medicines used in some pig farms have poor control effects, and Western medicines The non-standard use has also caused pork food with high drug residues and high toxicity, which affects food safety and is harmful to the human body. Drug residues have become one of the main factors affecting the safety of pork products
[0004] The CN101731488A patent application document discloses a Chinese herbal medicine additive for preventing diarrhea of ​​weaned piglets and pig feed thereof. The Chinese herbal medicine additive contains expensive Chinese medicinal materials such as Radix Polygoni Multiflori and Epimedium, and the cost is high, so it is not suitable for large-scale production; The smell of traditional Chinese medicine is very sensitive. If the taste of Chinese herbal medicine in feed additives is too strong, piglets will have anorexia reaction, which is not suitable for piglets to take orally, which will greatly affect the efficacy of the medicine.
[0005] The CN104013746A patent document discloses a traditional Chinese medicine composition for treating diarrhea in piglets. The composition contains a large amount of medicinal materials with cold nature such as gallinacea, Alisma, and Pulsatilla. If taken continuously for more than one week, it will damage the spleen and stomach and affect digestion and absorption. , not conducive to long-term use of piglets

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] (1) Weigh 12 parts of Atractylodes macrocephala, 15 parts of Gorgon, 8 parts of woody fragrance, 8 parts of clove, 17 parts of Magnolia officinalis, 15 parts of Bupleurum, 13 parts of Scutellaria baicalensis, 10 parts of Astragalus membranaceus, 10 parts of roasted licorice, 12 parts of Codonopsis pilosula, 3 parts of dried ginger, crushed to 80-120 mesh respectively;

[0036] (2) Add 15 times the mass of each traditional Chinese medicine to the crushed Atractylodes macrocephala, Gorgon officinalis, Magnolia officinalis officinalis Magnolia officinalis, Bupleurum radix and Radix Glycyrrhizae Radix Glycyrrhiza, and boil for 4 hours on high heat, and then use ethanol with 10 times the mass of each traditional Chinese medicine to reflux extract 3 Second, the ethanol concentration is 80vt%, and the extraction temperature is 65°C, and the extract is filtered with filter paper for use;

[0037] (3) Add 10 times of the quality of each Chinese medicine to the pulverized woody, ...

Embodiment 2

[0042] (1) Weigh 12 parts of Atractylodes Rhizome, 17 parts of Gorgon, 9 parts of Woody Fragrance, 9 parts of Clove, 17 parts of Magnolia Officinalis, 16 parts of Bupleurum, 11 parts of Scutellaria Scutellariae, 15 parts of Radix Astragali, 15 parts of Radix Glycyrrhizae, 12 parts of Codonopsis, 7 parts of dried ginger, crushed to 80-120 mesh respectively;

[0043] (2) Add 10 times the mass of each traditional Chinese medicine to the crushed Atractylodes Rhizoma Atractylodes Rhizome, Gorgon, Magnolia officinalis Magnolia officinalis, Bupleurum, Radix Astragali and Radix Glycyrrhiza, respectively, boil for 3 hours, and then use 10 times the mass of each traditional Chinese medicine to reflux extract 2 Second, the ethanol concentration is 75vt%, and the extraction temperature is 60°C, and the extract is filtered with filter paper for use;

[0044] (3) Add respectively 10 times of the quality of each Chinese medicine to the ground woody, clove, Codonopsis pilosula, Radix Codonops...

Embodiment 3

[0049] (1) Weigh 10 parts of Atractylodes macrocephala, 25 parts of Gorgon, 10 parts of woody fragrance, 12 parts of clove, 15 parts of Magnolia officinalis, 18 parts of Bupleurum, 10 parts of Scutellaria baicalensis, 12 parts of Astragalus membranaceus, 12 parts of roasted licorice, 10 parts of Codonopsis pilosula, 6 parts of dried ginger, crushed to 80-120 mesh respectively;

[0050] (2) Add 10 times the mass of each traditional Chinese medicine to the crushed Atractylodes macrocephala, Gorgon officinalis, Magnolia officinalis officinalis Magnolia officinalis, Bupleuri, Radix Astragali and Radix Glycyrrhizae Glycyrrhiza, respectively, boil for 2 hours with 10 times the mass of each traditional Chinese medicine, and then use 10 times the mass of each traditional Chinese medicine to reflux extract 1 Second, the ethanol concentration is 60vt%, and the extraction temperature is 50°C, and the extract is filtered with filter paper for use;

[0051] (3) Add water with 8 times the q...

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PUM

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Abstract

The invention provides a traditional Chinese medicine patch for preventing piglet diarrhea as well as a preparation method and application thereof, belonging to the field of veterinary drugs. The traditional Chinese medicine patch comprises the following components: 10-20 parts of largehead atractylodes rhizome, 15-25 parts of gordon euryale seed, 8-12 parts of costustoot, 8-12 parts of clove, 15-22 parts of officinal magnolia bark, 15-20 parts of radix bupleuri, 10-18 parts of baical skullcap root, 10-20 parts of radix astragali, 10-20 parts of liquorice root, 10-15 parts of radix codonopsis and 3-9 parts of dried ginger. The product can be directly applied to navels of piglets, is fast in medicine absorption, has the effect of overcoming the defects of poor palatability and slow absorption of oral medicines, has the functions of reducing the diarrhea rate, improving the immunities of the piglets and promoting development of digestive organs, has the advantages of nature, no toxic or side effect, no medicine resistance, no residues, fast excretion, and the like, has short course of treatment and high cure rate, has piglet diarrhea cure rate of 88.4%, achieves good treatment effects and does not irritate skins. The preparation process is simple and practicable, is low in cost and is suitable for industrial production.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a traditional Chinese medicine patch for preventing and treating piglet diarrhea, a preparation method and application thereof. Background technique [0002] In recent years, piglet diarrhea has become an important factor affecting the survival rate of piglets. Diarrhea is the most common disease in piglets. Since 2014, piglet epidemic diarrhea has broken out in the United States, and nearly 6 million piglets have died. Diarrhea has also occurred in many places since then. epidemic. Recently, epidemic diarrhea ransacked Japanese farms again, killing nearly 70,000 pigs. In the face of the epidemic sweeping the world, countries are stepping up the development of drugs against piglet diarrhea. [0003] At present, Western medicines that add chemicals or antibiotics to the feed are mostly used to prevent diarrhea in piglets. However, with the continuous emergence of d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/70A61P1/12A61P31/02A61P37/04
Inventor 杜雄伟李叶邹民发王玉山梁军陈朝喜
Owner DALIAN NATIONALITIES UNIVERSITY
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