Silica gel composition for itching relieving and repairing of scars

A composition and silicone gel technology, which is applied in the direction of drug combination, active ingredients of artificially synthesized polymer materials, emulsion delivery, etc., can solve the problem of aesthetics, unsatisfactory use of silicone gel film, restriction of daytime activities and work, etc. question

Inactive Publication Date: 2015-07-22
ZHEJIANG PROVINCE ZHUJI CITY ZHULISHEN MEDICAL SUPPLIES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patient dissatisfaction with using silicone gel patches over visible lesions due to aesthetic impact
The silicone gel film needs to be used continuously for 12 hours a day, which limits daytime activities and work to a certain extent

Method used

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  • Silica gel composition for itching relieving and repairing of scars

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Coating performance test of the composition in Example 1. The control sample was Kelo-cote, and the test site was the forearm of the participant. It is found through comparative testing that the composition in Example 1 can be easily coated, and the thickness of the coating layer of the composition in Example 1 is equivalent to the thickness of the gel layer of the Kelo-cote product.

[0038] The water vapor transmission rate test of the composition in Example 1 adopts the moisture permeable cup weighing method, and the testing instrument is a PERME? Bomi water vapor transmission rate tester. The reference sample for the water vapor transmission rate test of the composition in Example 1 is a collagen film. The test method is that the silicone gel composition in Example 1 is coated on the collagen film, and after 20 minutes the cyclopentasiloxane in the composition is allowed to volatilize, measure its water vapor transmission rate, and then divide by the pure collagen f...

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Abstract

Silica gel composition for itching relieving and repairing of scars comprises cross-linked PDMS (polydimethylsiloxane), PDMS, volatile annular siloxane and gaseous-phase silicon dioxide particles and is characterized by further comprising boronized polysiloxane. The silica gel is formed by compositing the cross-linked PDMS, the PDMS, the volatile annular siloxane, a reaction product of boric acid and hydroxy-terminated polydimethylsiloxane, the gaseous-phase silicon dioxide particles and the like. Through adjustment of the ratio of the cross-linked PDMS to the PDMS to the volatile annular siloxane to the reaction product of the boric acid and the hydroxy-terminated polydimethylsiloxane to the gaseous-phase silicon dioxide particles, the water vapor blocking performance, the air permeability, the paintability and the itching relieving performance of the composition are guaranteed.

Description

technical field [0001] The invention relates to a silicone gel composition for relieving itching and repairing scars. Background technique [0002] For superficial scars, hypertrophic scars, atrophic scars and keloids. The pathological difference between hypertrophic scar and normal scar lies in the thickening of collagen fibers in the deep part of the scar. Hypertrophic scars are manifested as protruding surfaces, irregular shapes, unevenness, flushing and hyperemia, and solid and tough texture. Keloids are the result of excessive proliferation of collagen fibers during the healing process of skin injuries. They appear as benign lumps that are higher than normal skin, have different shapes, and are red in color and hard. When the scar grows beyond a certain limit, various complications will occur, such as the destruction of appearance and dysfunction of function, etc., which will bring great physical pain and mental pain to the patient. [0003] Studies have shown that c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/80A61K33/24A61P17/04A61P17/00
Inventor 楼博孙萍雷蕾
Owner ZHEJIANG PROVINCE ZHUJI CITY ZHULISHEN MEDICAL SUPPLIES CO LTD
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