A stack of anti-cancer nuclide neutron knives in a three-irradiated block layout

Abstract

The invention belongs to cancericidal nuclide neutron knives and particularly discloses a cancericidal nuclide neutron knife adopting one-reactor and three-irradiation-seat layout. The side wall of a core of the neutron knife is sleeved with a side beryllium reflection ring, and a bottom beryllium reflection disc is mounted at the bottom of the core; a left aluminum contact shoe piece is arranged outside one side of the side beryllium reflection ring, a right graphite contact shoe piece is arranged outside the other side of the side beryllium reflection ring, and the left aluminum contact shoe piece and the right graphite contact shoe piece are inserted into a lower cylinder; the left side of the lower cylinder is adjacent to an aluminum horizontal mixed beam box wall layer, the other side of the lower cylinder is adjacent to a box wall layer of an aluminum horizontal thermal neutron column, box wall layers connected to the left and right of the lower cylinder are both arc-plate-shaped, and the exposure seats with different functions are constructed in boxes; a vertical epithermal neutron exposure seat is mounted below a base plate of the lower cylinder. Multiple patients can be irradiated by the anti-cancer nuclide neutron knife after one reactor startup, and simultaneous up-to-standard irradiation for patients suffering from different cancers can be realized.

Description

technical field [0001] The invention belongs to an anti-cancer nuclide neutron knife, that is, a nuclear reactor neutron source irradiation device for achieving boron or gadolinium neutron capture and treatment of cancer, and specifically relates to an anti-cancer nuclide neutron with a stack of three irradiation seats Knife. Background technique [0002] After more than 60 years of research on the application of boron neutron capture therapy (BNCT) at research reactors in various countries, beam current classifications based on different treatment parts have been formed: [0003] Cortical tumor irradiation (0-1.5cm) - thermal neutron beam; [0004] Human superficial tumor irradiation (1.5-4.5cm) - superheated neutron beam (mixed beam); [0005] Human deep tumor irradiation (4.5-7.0cm) - epithermal neutron beam; [0006] Ex vivo irradiation of organs (partial or whole) - thermal neutron column. [0007] In the current BNCT clinical reactor, only one thermal beam or one e...

AI Technical Summary

Problems solved by technology

[0007] In the current BNCT clinical reactor, only one thermal beam or one epithermal neutron beam is installed in one reactor. Although one beam in Japan has three functions (heat, mixing, and epithermal exchange), Argentina adopts the epithermal and epithermal neutron beam. Mixed one-beam dual-purpose design, but every time a function is set, the reactor must be shut down to adjust the thickness of the beam moderator and / or the thickness of the cadmium adjustment layer, as well as the adjustment of the reflection and shielding layer. After setting, it needs to be reviewed The parameters and performance of the new beam, the clinical use efficiency is low, it is only suitable for the current single case trial treatment, and cannot meet the needs of routine treatment in the future

[0008] At present, the heat beam of the neutron source in the prior art in China is only used for animal experiments or superficial tumor irradiation, the beam intensity of the super heat beam is too low, and the irradiation time required for treatment is too long

[0009] The BNCT routine treatment device can not only irradiate as many patients as possible at one time, but also take care of patients with different cancers to achieve the standard irradiation at the same time, which cannot be achieved by the neutron source device in the current technology.

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