Traditional Chinese medicine composition for treating lupus erythematosus

A technology of lupus erythematosus and composition, which is applied in the field of traditional Chinese medicine composition for treating lupus erythematosus and its preparation. The effect of improving efficiency

Inactive Publication Date: 2015-07-01
杜卫卫
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Modern medicine has not fully elucidated the fundamental pathogenesis of lupus erythematosus, and has not achieved particularly satisfactory curative effects in clinical treatment. Symptomatic and supportive treatment is still the main treatment. Drugs that target part of the pathogenesis or mechanism, but the complexity and diversity of the pathogenesis of lupus erythematosus often cannot achieve satisfactory therapeutic effects by targeting only one pathogenesis or pathogenesis

Method used

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  • Traditional Chinese medicine composition for treating lupus erythematosus
  • Traditional Chinese medicine composition for treating lupus erythematosus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0148] Embodiment 1 The specific preparation of injection 1

[0149] Put 20 mg of Shangkeshu, 20 mg of marigold inflorescence, 20 mg of Dayeguanmen root, 20 mg of Sarcorrhizae vine root, 20 mg of Xiaguovine, 45 mg of Sanzuanfeng, 45 mg of Xiaoxue ginseng, 45 mg of Dapaotong, and Mopangen 45 mg, Ten Great Contribution Leaf 55 mg, Panax notoginseng 55 mg, Hydra 55 mg, Two-leaf Maihecao 30 mg, Oat Grass 30 mg, Chiselia 30 mg, Dragon Boat Flower 30 mg, Spatholobus 30 mg , Saw Saw Vine 30 mg, Wuling Zhi 10 mg, Sanxiaocao 10 mg, Sophora japonica 10 mg, Little Golden Cherry 10 mg, Mytharis 10 mg, Selina 10 mg, Comfrey 10 mg, Achyranthes bidentata 10 mg , dodder 10 mg, raspberry 10 mg, aconite 10 mg, lantana flower 10 mg, lotus leaf 10 mg, lotus seed heart 10 mg, grape 10 mg, mulberry 10 mg, ginseng leaf 10 mg, Tibetan green fruit 10 mg, ginkgo leaf 10 mg of lily flower, 10 mg of lily flower, 10 mg of albizia juniper flower, 10 mg of peony flower, and 10 mg of ginseng flower are drie...

Embodiment 2

[0150] Embodiment 2 Toxicology experiment

[0151] Choose 60 KM mice, divide into treatment group and matched group at random according to body weight, every group is 30, male and female half and half, before administration fasting can't help water 12 hours, the present invention treats group mice according to the administration of 0.25ml / 10g The drug volume was administered intravenously; the control group was given intragastric water. Immediately after administration, observe the reaction of the animal, including the animal's shape, behavior, mental state, appetite, urine and stool and its color, whether there are abnormal secretions in the fur, nose, eyes, and mouth, and the death of the animal. Dead animals should be autopsyed in time , Histopathological examination was performed if there were visible lesions. Observed every 1 hour on the first day of administration, and then observed once a day for 7 consecutive days to record animal toxicity and death. Weigh the body w...

Embodiment 3

[0152] Embodiment 3 The specific preparation of injection 2

[0153]Take 23 mg of Shangkeshu, 23 mg of Marigold inflorescence, 23 mg of Dayeguanmen root, 23 mg of Sarcophagus vine root, 23 mg of Xiaguovine, 46 mg of Sanzuanfeng, 46 mg of Xiaoxue ginseng, 46 mg of Dapaotong, and Mopangen 46 mg, 58 mg of Shigonggong leaves, 58 mg of Panax notoginseng, 58 mg of nine-headed grass, 32 mg of two-leaf maidengrass, 32 mg of oat grass, 32 mg of chisel, 32 mg of dragon boat flower, and 32 mg of Milletah , Saw Saw Vine 32 mg, Wuling Zhi 12 mg, Sanxiaocao 12 mg, Sophora japonica 12 mg, Little Golden Cherry 12 mg, Mytharis 12 mg, Selina 12 mg, Comfrey 12 mg, Achyranthes bidentata 12 mg , dodder 12 mg, raspberry 12 mg, aconite 12 mg, lantana flower 12 mg, lotus leaf 12 mg, lotus seed heart 12 mg, grape 12 mg, mulberry 12 mg, ginseng leaf 12 mg, Tibetan green fruit 12 mg, ginkgo leaf 12 mg, 12 mg of lily flower, 12 mg of albizia juniper flower, 12 mg of peony flower, and 12 mg of ginseng fl...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating lupus erythematosus. The traditional Chinese medicine composition is prepared from the following raw herbal materials: rostrate lepidogrammitis, marigold inflorescence, many-nerved bauhinia root, grossedentate clematis root, stem and leaf of slender-spike gouania, Japanese spicebush bark, woolly lespedeza root, delavay schefflera root, indian abutilon root, Chinese mahonia leaf, sanchi flower, slender silene, false lily of the valley, oat grass, leonurus pseudomacranthus, ixora chinensis, suberect spatholobus stem and bunge bedstraw herb with effects of clearing away heat and toxic materials, clearing liver heat, cooling blood to remove stasis, and relaxing tendons and muscles, as well as excrementum pteropi, herb of white clover, flos sophorae, rosa taiwanensis, Chinese blister beetle, ophiopogon latifolius, lithospermum, radix achyranthis bidentatae, seed of Chinese dodder, raspberry, monkshood, rhododendron delavayi, lotus leaf, lotus plumule, grapes, mulberry, ginseng leaf, myrobalan, ginkgo leaf, greenish lily flower, albizia flower, peony and ginseng flower with effects of tonifying the kidneys and detoxifying, cooling blood to remove stasis, nourishing yin and tonifying yang, soothing the livers and benefiting qi, is remarkable in curative effect for lupus erythematosus, and can be used for supplementing qi of a human body, strengthening immunity and improving the effective rate of treating lupus erythematosus.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating lupus erythematosus and a preparation method thereof. Background technique [0002] Lupus erythematosus (LE) is a typical autoimmune connective tissue disease, which is more common in women aged 15-40. [0003] The main clinical features are fever of varying degrees, edematous erythema on exposed skin sites, joint pain, and oropharyngeal ulcers. If the heart is involved, there will be pericarditis, myocarditis or endocarditis, and even heart failure. Kidney involvement occurs nephritis, nephrotic syndrome, renal insufficiency and so on. When the digestive system is involved, hepatitis, gastrointestinal ulcer bleeding and so on will appear. If the nervous system is involved, epilepsy, meningitis, and cerebrovascular accidents will occur. LE mainly affects young women. The acute type has sudden onse...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P37/02A61K35/64A61K35/24
Inventor 杜卫卫
Owner 杜卫卫
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